Catalog No.
YHC97301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu31-Thr172
Predicted molecular weight
17.13 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P13385
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Cripto-1 growth factor, Teratocarcinoma-derived growth factor 1, TDGF1, CRIPTO, Epidermal growth factor-like cripto protein CR1, CRGF
In silico prediction of GRP78-CRIPTO binding sites to improve therapeutic targeting in glioblastoma., PMID:40360533
Inhibition of Fin Regeneration in Fathead Minnow (Pimephales promelas) by a Potent Synthetic Glucocorticoid and Development of Adverse Outcome Pathway 334., PMID:40326831
Cripto-1 acts as a molecular bridge linking nodal to ALK4 via distinct structural domains., PMID:39840816
Protogenin facilitates trunk-to-tail HOX code transition via modulating GDF11/SMAD2 signaling in mammalian embryos., PMID:39702818
CRIPTO's multifaceted role in driving aggressive prostate cancer unveiled by in vivo, organoid, and patient data., PMID:39592836
Decrypting the phylogenetics history of EGF-CFC proteins Cripto and Cryptic., PMID:39257814
Human Genetics of Ventricular Septal Defect., PMID:38884729
Lineage regulators TFAP2C and NR5A2 function as bipotency activators in totipotent embryos., PMID:38243114
Exploring biomarkers in trigeminal neuralgia patients operated with microvascular decompression: A comparison with multiple sclerosis patients and non-neurological controls., PMID:38158702
Recombinant humanized Fab fragments targeting the CFC domain of human Cripto-1., PMID:38150919
CRIPTO-based micro-heterogeneity of mouse muscle satellite cells enables adaptive response to regenerative microenvironment., PMID:38056454
Cripto Is Targeted by miR-1a-3p in a Mouse Model of Heart Development., PMID:37569627
Testicular Germ Cell Tumor Tissue Biomarker Analysis: A Comparison of Human Protein Atlas and Individual Testicular Germ Cell Tumor Component Immunohistochemistry., PMID:37508506
Pseudogene TDGF1P3 regulates the proliferation and metastasis of colorectal cancer cells via the miR-338-3p-PKM2 axis., PMID:36436343
Liver receptor homolog 1 (LRH-1) regulates follicle vasculature during ovulation in mice., PMID:36173805
Regulation of Nodal signaling propagation by receptor interactions and positive feedback., PMID:36149406
GWAS of Chronic Spontaneous Urticaria Reveals Genetic Overlap with Autoimmune Diseases, Not Atopic Diseases., PMID:35933036
The Impact of Activin A on Fetal Gonocytes: Chronic Versus Acute Exposure Outcomes., PMID:35721752
CRIPTO-1 Is Immunolocalized in the Syncytiotrophoblast of Ampullary Pregnancies., PMID:35434129
Oncofetal Protein CRIPTO Is Involved in Wound Healing and Fibrogenesis in the Regenerating Liver and Is Associated with the Initial Stages of Cardiac Fibrosis., PMID:34943832
Whence CRIPTO: The Reemergence of an Oncofetal Factor in 'Wounds' That Fail to Heal., PMID:34576327
miR-3929 Inhibits Proliferation and Promotes Apoptosis by Downregulating Cripto-1 Expression in Cervical Cancer Cells., PMID:34569498
Liver-specific over-expression of Cripto-1 in transgenic mice promotes hepatocyte proliferation and deregulated expression of hepatocarcinogenesis-related genes and signaling pathways., PMID:34517344
Cripto-1 as a Key Factor in Tumor Progression, Epithelial to Mesenchymal Transition and Cancer Stem Cells., PMID:34502188
Investigating the role of EGF-CFC gene family in recurrent pregnancy loss through bioinformatics and molecular approaches., PMID:34498535
Cripto favors chondrocyte hypertrophy via TGF-β SMAD1/5 signaling during development of osteoarthritis., PMID:34357595
The pattern of nodal morphogen signaling is shaped by co-receptor expression., PMID:34036935
[Expression and Prognostic Value of Cripto-1 in Pancreatic Cancer]., PMID:33966694
Maternal Cripto is critical for proper development of the mouse placenta and the placental vasculature., PMID:33730615
Maternal Cripto is required for proper uterine decidualization and peri-implantation uterine remodeling., PMID:33590845
A Novel Artificially Humanized Anti-Cripto-1 Antibody Suppressing Cancer Cell Growth., PMID:33567764
Gastruloid Development Competence Discriminates Different States of Pluripotency., PMID:33482102
CRIPTO antagonist ALK4L75A-Fc inhibits breast cancer cell plasticity and adaptation to stress., PMID:33187540
E2A regulates neural ectoderm fate specification in human embryonic stem cells., PMID:33144398
MasterPATH: network analysis of functional genomics screening data., PMID:32928103
PGAP6, a GPI-specific phospholipase A2, has narrow substrate specificity against GPI-anchored proteins., PMID:32816994
A Prognostic Model Based on the Immune-related Genes in Colon Adenocarcinoma., PMID:32788867
Cripto-1 promotes tumor invasion and predicts poor outcomes in hepatocellular carcinoma., PMID:32649753
Cripto-1 promotes tumor invasion and predicts poor outcomes in hepatocellular carcinoma., PMID:32648918
Proteomic analysis of the cardiac myocyte secretome reveals extracellular protective functions for the ER stress response., PMID:32339566
Zebrafish Microenvironment Elevates EMT and CSC-Like Phenotype of Engrafted Prostate Cancer Cells., PMID:32225005
Structure-based design of small bicyclic peptide inhibitors of Cripto-1 activity., PMID:32215602
The Function and Prognostic Significance of Cripto-1 in Colorectal Cancer., PMID:32157913
Prognostic value of cripto-1 expression in non-small-cell lung cancer patients: a systematic review and meta-analysis., PMID:32134335
Derivation of notochordal cells from human embryonic stem cells reveals unique regulatory networks by single cell-transcriptomics., PMID:31840817
KRAS mutation and abnormal expression of Cripto-1 as two potential candidate biomarkers for detection of colorectal cancer development., PMID:31692030
Detection of small numbers of iPSCs in different heterogeneous cell mixtures with highly sensitive droplet digital PCR., PMID:31578676
Cripto-1 localizes to dynamic and shed filopodia associated with cellular migration in glioblastoma cells., PMID:31543278
Cripto-1 expression in patients with clear cell renal cell carcinoma is associated with poor disease outcome., PMID:31455359
Visualization of sequential conversion of human intermediately reprogrammed stem cells into iPS cells., PMID:31386786
For research use only. Not for human or drug use.
