Catalog No.
YHE55402
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys22-Lys89
Predicted molecular weight
10.26 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P48061-2
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Intercrine reduced in hepatomas, hSDF-1, Stromal cell-derived factor 1, SDF-1, Pre-B cell growth-stimulating factor, SDF1, SDF1A, C-X-C motif chemokine 12, SDF1B, CXCL12, IRH, PBSF, hIRH
USP48 protects against myocardial ischemia-reperfusion injury by stabilizing and upregulating CNN1 in type 1 diabetes mice., PMID:40513941
Multidirectional therapeutic effects of synthesized HMGB1 peptide on liver cirrhosis in mice., PMID:40503100
Increased Fascin1 and Pak1 Expressions Enhance Age-Associated B-Cell Actin Cytoskeleton Remodeling and Motility., PMID:40500987
CXCL12 expression and the survival of patients with gastric cancer: a meta-analysis., PMID:40481962
Unraveling anti-atherosclerosis mechanism of anthocyanins from Xinjiang wild cherry plum (Prunus divaricata Ledeb) via network pharmacology and molecular docking., PMID:40478326
Dissecting the tumor microenvironment in primary breast angiosarcoma: insights from single-cell RNA sequencing., PMID:40474296
Investigating the mechanism of Gentiopicroside in rheumatoid arthritis through network pharmacology, molecular docking, and experimental validation., PMID:40473698
Neuroinflammatory chemokine networks in transgenic models of Alzheimer's disease: A comparative multi-compartmental analysis., PMID:40472196
MAP1B regulates the odontogenic potential of human dental pulp cells via p53/CXCL12 signalling: A laboratory investigation., PMID:40457547
CXCL12 links bladder cancer and diabetes as a potential biomarker., PMID:40447619
Single-cell RNAseq of Angiotensin II-induced abdominal aortic tissue identifies aneurysm-associated cell clusters in C57BL/6J mice., PMID:40440080
Unraveling the mechanisms of irAEs in endometrial cancer immunotherapy: insights from FAERS and scRNA-seq data., PMID:40436981
Bcl-3 depletion prevent autoimmune hepatitis of mice through CXCR4/CXCL12 pathway., PMID:40435820
Stromal Cell-Derived Factor-1, P-Selectin, and Advanced Oxidation Protein Products with Mitochondrial Dysfunction Concurrently Impact Cerebral Vessels in Patients with Normoalbuminuric Diabetic Kidney Disease and Type 2 Diabetes Mellitus., PMID:40429625
Prognostic Significance of CLDN1, INHBA, and CXCL12 in Colon Adenocarcinoma: A Multi-Omics and Single-Cell Approach., PMID:40426863
Gold-silica hybrid nanolabels decorated with recognition and signaling bioreagents for enhanced electrochemical immunodetection of chemokine ligand-12 in colorectal cancer early diagnosis and monitoring., PMID:40425890
Single-cell atlas of endothelial cells in atherosclerosis: identifying C1 CXCL12+ ECs as key proliferative drivers for immunological precision therapeutics in atherosclerosis., PMID:40421026
Triazole-quinoxaline attenuates epithelial-to-mesenchymal transition by suppressing the Wnt/β-catenin pathway in human colorectal cancer cells., PMID:40414329
NLRP3 activation induces BBB disruption and neutrophil infiltration via CXCR2 signaling in the mouse brain., PMID:40413505
Distribution of CCR5-Delta32, CCR2-64I, and SDF1-3'A host genetic factors in HIV-infected and uninfected individuals in Luanda, Angola., PMID:40413451
CXCR4+ mammary gland macrophageal niche promotes tumor initiating cell activity and immune suppression during tumorigenesis., PMID:40413176
GliaTrap is a biodegradable, non-swelling and non-inflammatory hydrogel with tuned release of CXCL12 to attract migrating glioblastoma cells., PMID:40404745
Decoding the function of cancer-associated fibroblasts in osteosarcoma: Molecular pathways, therapeutic approaches and prognostic significance., PMID:40404112
Periosteal skeletal stem cells can migrate into the bone marrow and support hematopoiesis after injury., PMID:40401637
Highly Specific Cytokine Receptor-Targeting Chimeras for Targeted Membrane Protein Degradation and Sensitization of Osimertinib in EGFR-Mutated Non-Small-Cell Lung Cancer., PMID:40401615
6-Shogaol inhibits the cell motility of prostate cancer cells by suppressing the PI3K/AKT/mTOR and Ras/Raf/MAPK pathways with comparable effects to paclitaxel treatment., PMID:40397499
GPR15LG binds CXCR4 and synergistically modulates CXCL12-induced cell signaling and migration., PMID:40394646
Beneficial but diverse influence of custom-designed hydrogels modified with IL-4 and SDF-1 peptides on selected populations of cells essential for skeletal muscle regeneration., PMID:40381767
Polyphenol and metal ion-reinforced supermolecular hydrogels incorporating nanofiber drug and peptide for annulus fibrosus regeneration., PMID:40365273
Mercury Bioaccumulation in Female Breast Cancer Is Associated to CXCR4 Expression., PMID:40362664
Regulation of Immune-Related Gene Expression by Salinity-Induced HPI Axis in Large Yellow Croaker, Larimichthys crocea., PMID:40362534
Multi-omic analysis reveals a CAF-stemness-governed classification in HCC liver transplant recipients beyond the Milan criteria., PMID:40355422
Silencing HMGB1 secretion inhibited EV71-induced blood-brain barrier dysfunction and neural inflammation by depressing astrocyte activation via sHh signal blockage., PMID:40349912
Ginsenoside Rg1 targets TLR2 to inhibit the NF-κB signaling pathway and ameliorate hematopoietic support of mesenchymal stromal cells., PMID:40348305
Estrogen promotes autophagy in the mammary epithelial cells of dairy sheep via the CXCL12/CXCR4 axis., PMID:40341494
Critical role of the potential O-linked glycosylation sites of CXCR4 in cell migration and bone marrow homing of hematopoietic stem progenitor cells., PMID:40338020
CXCL12 Engages Cortical Inhibitory Neurons to Enhance Dendritic Spine Plasticity and Structured Network Activity., PMID:40335156
Fibroblast activation protein-α interacts with CXCL12 to inactivate canonical Wnt signaling and regulate osteoblast differentiation., PMID:40327708
Exosomal miR-122-5p for regulation of secretory functions of fibroblasts and promotion of breast cancer metastasis by targeting MKP-2: an experimental study., PMID:40320567
Role of CXCR4/SDF1 signaling in the initial migration of cardiac neural crest cells., PMID:40319820
Single-cell RNA sequencing reveals a fibroblast gene signature that promotes T-cell infiltration in muscle-invasive bladder cancer., PMID:40319103
SDF-1α mRNA therapy in peripheral artery disease., PMID:40314870
G protein-coupled receptor GPR182 negatively regulates sprouting angiogenesis via modulating CXCL12-CXCR4 axis signaling., PMID:40314798
Physical exercise promotes white matter repair after ischemic stroke., PMID:40313089
Proteomics suggests the role of Cxcl12 secreted by hucMSCs in the treatment of lipopolysaccharide-acute lung injury., PMID:40311750
CXCL12+ fibroblastic reticular cells in lymph nodes facilitate immune tolerance by regulating T cell-mediated alloimmunity., PMID:40309773
Transcriptome associated with single-cell analysis reveal the role of S-palmitoylation in coronary artery disease., PMID:40307438
Cellular communication networks in fibrosis: Insights from the MASLD pig model., PMID:40304567
Activation of CXCR7 exerts an inhibitory effect on adipogenesis through regulation of β-arrestin2/Wnt and AKT signalling., PMID:40302245
Plasma Exchange vs. Immunoadsorption: Effects on Immunological Markers and Predictive Value in Steroid-Refractory MS Attacks., PMID:40292037
For research use only. Not for human or drug use.
