Catalog No.
YHN43801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu89-Arg501
Predicted molecular weight
47.26 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9P258
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Protein RCC2, Telophase disk protein of 60 kDa, RCC2, RCC1-like protein TD-60, KIAA1470, TD60
High Sugar Induced RCC2 Lactylation Drives Breast Cancer Tumorigenicity Through Upregulating MAD2L1., PMID:40145796
Identification of RCC2 as a Risk Gene Associated With Basal Cell Carcinoma and Experimental Validation., PMID:40129067
Inhibition of glutathione peroxidase 4 suppresses gastric cancer peritoneal metastasis via regulation of RCC2 homeostasis., PMID:39908861
m6A-modified exosome-derived circHIF1α binding to KH domain of IGF2BP3 mediates DNA damage and arrests G1/S transition phase to resists bacterial infection in bacteremia., PMID:39443946
Significance of RCC2, Rac1 and p53 Expression in Breast Infiltrating Ductal Carcinoma; An Immunohistochemical Study., PMID:39118792
circRNA-0015004 act as a ceRNA to promote RCC2 expression in hepatocellular carcinoma., PMID:39043840
PTBP1-mediated biogenesis of circATIC promotes progression and cisplatin resistance of bladder cancer., PMID:38993556
NudCL2 is required for cytokinesis by stabilizing RCC2 with Hsp90 at the midbody., PMID:38801297
Promotive actions of lncRNA EBLN3P involved in cervical cancer progression via interacting with miR-29c-3p and TAF15 to modify RCC2., PMID:38555043
The temporal protein signature analyses of developing human deciduous molar tooth germ., PMID:38522031
RCC2 promotes prostate cancer cell proliferation and migration through Hh/GLI1 signaling pathway and cancer stem-like cells., PMID:38008751
Pathogenic bacteria exploit transferrin receptor transcytosis to penetrate the blood-brain barrier., PMID:37733740
Integrative analysis of the proteome and transcriptome in gastric cancer identified LRP1B as a potential biomarker., PMID:36606427
LncRNA HOTAIR enhances RCC2 to accelerate cervical cancer progression by sponging miR-331-3p., PMID:36593385
Comprehensive analysis of the expression profile and clinical implications of regulator of chromosome condensation 2 in pan-cancers., PMID:36441563
A pan‑cancer analysis of RCC2 and its interaction with HMGA2 protein in an in vitro model of colorectal cancer cells., PMID:36340602
The mitotic regulator RCC2 promotes glucose metabolism through BACH1-dependent transcriptional upregulation of hexokinase II in glioma., PMID:36116740
CORO1C, a novel PAK4 binding protein, recruits phospho-PAK4 at serine 99 to the leading edge and promotes the migration of gastric cancer cells., PMID:35593474
The m6A reader IGF2BP3 promotes acute myeloid leukemia progression by enhancing RCC2 stability., PMID:35217832
Co-Delivery of Paclitaxel and shMCL-1 by Folic Acid-Modified Nonviral Vector to Overcome Cancer Chemotherapy Resistance., PMID:34928100
Identification of Key Deregulated RNA-Binding Proteins in Pancreatic Cancer by Meta-Analysis and Prediction of Their Role as Modulators of Oncogenesis., PMID:34912796
BRD4 drives esophageal squamous cell carcinoma growth by promoting RCC2 expression., PMID:34750516
Exercise training effects on natural killer cells: a preliminary proteomics and systems biology approach., PMID:33965896
Roles of regulator of chromosome condensation 2 in cancer: Beyond its regulatory function in cell cycle., PMID:33824700
Regulator of Chromosome Condensation 2 Modulates Cell Cycle Progression, Tumorigenesis, and Therapeutic Resistance., PMID:33521058
Prediction of relapse-free survival according to adjuvant chemotherapy and regulator of chromosome condensation 2 (RCC2) expression in colorectal cancer., PMID:33219056
MicroRNA-191 modulates cisplatin-induced DNA damage response by targeting RCC2., PMID:32803782
RCC2 Promotes Esophageal Cancer Growth by Regulating Activity and Expression of the Sox2 Transcription Factor., PMID:32801160
RCC2 contributes to tumor invasion and chemoresistance to cisplatin in hepatocellular carcinoma., PMID:32239438
MicroRNA-331-3p inhibits proliferation and metastasis of ovarian cancer by targeting RCC2., PMID:31749881
High throughput circRNA sequencing analysis reveals novel insights into the mechanism of nitidine chloride against hepatocellular carcinoma., PMID:31506425
XPO1 is a critical player for bortezomib resistance in multiple myeloma: A quantitative proteomic approach., PMID:31465861
Dissecting the cytochrome c2-reaction centre interaction in bacterial photosynthesis using single molecule force spectroscopy., PMID:31320503
RCC2 promotes proliferation and radio-resistance in glioblastoma via activating transcription of DNMT1., PMID:31277942
RCC2, a regulator of the RalA signaling pathway, is identified as a novel therapeutic target in cisplatin-resistant ovarian cancer., PMID:30768358
High-performance gene expression and knockout tools using sleeping beauty transposon system., PMID:30534207
LncRNA LCPAT1 is involved in DNA damage induced by CSE., PMID:30509493
miR-196a Promotes Proliferation and Inhibits Apoptosis of Immature Porcine Sertoli Cells., PMID:30427699
LncRNA LCPAT1 Mediates Smoking/ Particulate Matter 2.5-Induced Cell Autophagy and Epithelial-Mesenchymal Transition in Lung Cancer Cells via RCC2., PMID:29913439
Differential Proteomic Analysis between Small Cell Lung Carcinoma (SCLC) and Pulmonary Carcinoid Tumors Reveals Molecular Signatures for Malignancy in Lung Cancer., PMID:29888431
The β3-integrin endothelial adhesome regulates microtubule-dependent cell migration., PMID:29794156
RCC2 over-expression in tumor cells alters apoptosis and drug sensitivity by regulating Rac1 activation., PMID:29321004
RCC2 is a novel p53 target in suppressing metastasis., PMID:28869598
Crystal structure of human WBSCR16, an RCC1-like protein in mitochondria., PMID:28608466
Overexpression of RCC2 Enhances Cell Motility and Promotes Tumor Metastasis in Lung Adenocarcinoma by Inducing Epithelial-Mesenchymal Transition., PMID:28606921
Epigenetically altered miR-1247 functions as a tumor suppressor in pancreatic cancer., PMID:28460450
Transcriptional and Posttranslational Regulation of Nucleotide Excision Repair: The Guardian of the Genome against Ultraviolet Radiation., PMID:27827925
Dependence of the structure and mechanics of metaphase chromosomes on oxidized cysteines., PMID:27145786
The epidermal growth factor receptor decreases Stathmin 1 and triggers catagen entry in the mouse., PMID:26661905
TD-60 links RalA GTPase function to the CPC in mitosis., PMID:26158537
For research use only. Not for human or drug use.
