Catalog No.
YHF60301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Arg317
Predicted molecular weight
79.11 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P63244
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
RACK1, Human lung cancer oncogene 7 protein, Guanine nucleotide-binding protein subunit beta-like protein 12.3, GNB2L1, Cell proliferation-inducing gene 21 protein, Guanine nucleotide-binding protein subunit beta-2-like 1, Receptor of activated protein C kinase 1, Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed, Receptor for activated C kinase, Small ribosomal subunit protein RACK1, HLC-7
RACK1 promotes the development and function of alveolar macrophages through directly binding to and stabilizing PPARγ., PMID:40512793
Antimalarial drug artemisinin stabilizes PfRACK1 binding to the ribosome., PMID:40480224
Distinct non-canonical translation initiation modes arise for specific host and viral mRNAs during poxvirus-induced shutoff., PMID:40437296
OTUD1 deficiency attenuates myocardial ischemia/reperfusion induced cardiomyocyte apoptosis by regulating RACK1 phosphorylation., PMID:40394237
A RACK1 family protein regulates pathogenicity of Peronophythora litchii by acting as a scaffold for MAPK signal modules., PMID:40356437
Inhibition of RACK1-Mediated NLRP3 Oligomerization (Active Conformation) Ameliorates Acute Respiratory Distress Syndrome., PMID:40349158
Optimal Reference Genes for Gene Expression Analysis of Overmating Stress-Induced Aging and Natural Aging in Male Macrobrachium rosenbergii., PMID:40331929
Exploring the Therapeutic Potential of Evodia rutaecarpa in Early-Onset Pancreatic Cancer: A Network Pharmacology and Molecular Docking Approach., PMID:40148293
RACK7 Interacts with PRC2 Complex to Regulate Astrocyte Development., PMID:40125808
Inhibition of Aberrant Activated Fibroblast-Like Synoviocytes in Rheumatoid Arthritis by Leishmania Peptide via the Regulation of Fatty Acid Synthesis Metabolism., PMID:40125636
HucMSC-Ex alleviates inflammatory bowel disease by regulating O-GlcNAcylation modification of RACK1 in intestinal epithelial cells., PMID:40068238
Nematode serine protease inhibitor SPI-I8 negatively regulates host NF-κB signalling by hijacking MKRN1-mediated polyubiquitination of RACK1., PMID:40032982
Exploration of RNA-binding proteins identified RPS27 as a potential regulator associated with Kaposi's sarcoma development., PMID:40016701
Rack1 promotes breast cancer stemness properties and tumorigenesis through the E2F1-SOX2 axis., PMID:39939870
The scaffold protein RACK1 regulates root growth and gravitropic response by recruiting PINOID to phosphorylate the auxin efflux transporter PIN-FORMED2., PMID:39912541
The short conserved region-2 of LARP4 interacts with ribosome-associated RACK1 and promotes translation., PMID:39898547
Exploratory analysis of a Novel RACK1 mutation and its potential role in epileptic seizures via Microglia activation., PMID:39891152
LRP11 facilitates lipid metabolism and malignancy in hepatocellular carcinoma by stabilizing RACK1 through USP5 regulation., PMID:39891099
CBX2 suppresses interferon signaling to diminish tumor immunogenicity via a noncanonical corepressor complex., PMID:39883845
Protein kinase a suppresses antiproliferative effect of interferon-α in hepatocellular carcinoma by activation of protein tyrosine phosphatase SHP2., PMID:39826687
Hypoxia-induced degradation of FTO promotes apoptosis by unmasking RACK1-mediated activation of MTK1-JNK1/2 pathway., PMID:39805423
Ribosome customization and functional diversification among P-stalk proteins regulate late poxvirus protein synthesis., PMID:39786991
RACK1 MARylation regulates translation and stress granules in ovarian cancer cells., PMID:39760726
SENP3 inhibition suppresses hepatocellular carcinoma progression and improves the efficacy of anti-PD-1 immunotherapy., PMID:39755756
Targeting CDK2 Confers Vulnerability to Lenvatinib Via Driving Senescence in Anaplastic Thyroid Cancer., PMID:39716890
Role of Vigilin and RACK1 in dengue virus-Aedes aegypti-Wolbachia interactions., PMID:39714171
Disruption of Epithelial Barrier Integrity via Altered GILZ/c-Rel/RACK1 Signaling in Inflammatory Bowel Disease., PMID:39693354
Insights into the regulation of mRNA translation by scaffolding proteins., PMID:39641595
Bone marrow mesenchymal stem cell-derived exosomal miR-181a-5p promotes M2 macrophage polarization to alleviate acute pancreatitis through ZEB2-mediated RACK1 ubiquitination., PMID:39614664
Coronavirus nucleocapsid protein enhances the binding of p-PKCα to RACK1: Implications for inhibition of nucleocytoplasmic trafficking and suppression of the innate immune response., PMID:39602452
iTRAQ-Based Proteomic Analysis of Spontaneous Achilles Tendon Rupture., PMID:39601082
VRK2 inhibits the replication of infectious bursal disease virus by phosphorylating RACK1 and suppressing apoptosis., PMID:39579830
The short conserved region-2 of LARP4 interacts with ribosome-associated RACK1 and promotes translation., PMID:39554137
Unveiling RACK1: a key regulator of the PI3K/AKT pathway in prostate cancer development., PMID:39537875
eIF3d specialized translation requires a RACK1-driven eIF3d binding to 43S PIC in proliferating SH-SY5Y neuroblastoma cells., PMID:39477045
RACK1 contributes to the upregulation of embryonic genes in a model of cardiac hypertrophy., PMID:39465301
An Antagonist Antibody That Inhibits Cancer Cell Growth In Vitro through RACK1., PMID:39458945
Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1-mediated fatty acid synthesis., PMID:39425259
Mtb/HIV co-infection immune microenvironment subpopulations heterogeneity., PMID:39405943
Ribosomes hibernate on mitochondria during cellular stress., PMID:39379376
RACK1 inhibits ferroptosis of cervical cancer by enhancing SLC7A11 core-fucosylation., PMID:39356381
RACK1 and NEK7 mediate GSDMD-dependent macrophage pyroptosis upon Streptococcus suis infection., PMID:39334337
The protective role of RACK1 in hepatic ischemia‒reperfusion injury-induced ferroptosis., PMID:39292271
Rack1 regulates B-cell development and function by binding to and stabilizing the transcription factor Pax5., PMID:39256480
Repeated stress to the skin amplifies neutrophil infiltration in a keratin 17- and PKCα-dependent manner., PMID:39159283
RACK1 links phyB and BES1 to coordinate brassinosteroid-dependent root meristem development., PMID:39149918
OTUD6 deubiquitination of RPS7/eS7 on the free 40 S ribosome regulates global protein translation and stress., PMID:39127721
Deciphering the neuroprotective mechanisms of RACK1 in cerebral ischemia-reperfusion injury: Pioneering insights into mitochondrial autophagy and the PINK1/Parkin axis., PMID:39097918
Inhibition of K63 ubiquitination by G-Protein pathway suppressor 2 (GPS2) regulates mitochondria-associated translation., PMID:39094987
RACK1 enhances STAT3 stability and promotes T follicular helper cell development and function during blood-stage Plasmodium infection in mice., PMID:39024388
For research use only. Not for human or drug use.
