Catalog No.
YHN43701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Cys251-Glu510
Predicted molecular weight
31.42 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8WUM9
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
GLVR1, Gibbon ape leukemia virus receptor 1, GLVR-1, PIT1, Phosphate transporter 1, Leukemia virus receptor 1 homolog, PiT-1, Solute carrier family 20 member 1, Sodium-dependent phosphate transporter 1, SLC20A1
Type III sodium-dependent inorganic phosphate transporters are required for the phenotypes in human brain microvascular endothelial cells., PMID:40221005
Lactobacillus acidophilus potentiates oncolytic virotherapy through modulating gut microbiota homeostasis in hepatocellular carcinoma., PMID:40195307
Genetic susceptibility and potential therapeutic targets of unruptured intracranial aneurysms: A genome-wide study based on Mendelian randomization., PMID:39847889
Sodium-dependent phosphate transporter PiT1/SLC20A1 as the receptor for the endogenous retroviral envelope syncytin-B involved in mouse placenta formation., PMID:39287391
Spitz Melanoma With SLC20A1::ALK Fusion: A Novel Fusion Previously Undescribed in Spitz Melanocytic Neoplasm., PMID:38941542
Correlating Material Properties to Osteoprotegerin Expression on Nanoparticulate Mineralized Collagen Glycosaminoglycan Scaffolds., PMID:38885525
Homeostatic coordination of cellular phosphate uptake and efflux requires an organelle-based receptor for the inositol pyrophosphate IP8., PMID:38833370
Uropathogenic Escherichia coli infection: innate immune disorder, bladder damage, and Tailin Fang II., PMID:38638825
SLC20A1 is a prospective prognostic and therapy response predictive biomarker in head and neck squamous cell carcinoma., PMID:38412319
Slc20a1 and Slc20a2 regulate neuronal plasticity and cognition independently of their phosphate transport ability., PMID:38195526
Human peritoneal tight junction, transporter and channel expression in health and kidney failure, and associated solute transport., PMID:37833387
Bone-derived PDGF-BB drives brain vascular calcification in male mice., PMID:37815871
Identification of co-diagnostic effect genes for aortic dissection and metabolic syndrome by multiple machine learning algorithms., PMID:37684281
High sodium promotes the secretion and synthesis of PTH through PiT-1-IKKβ pathway in parathyroid gland in vitro., PMID:37337945
Computational analysis of sodium-dependent phosphate transporter SLC20A1/PiT1 gene identifies missense variations C573F, and T58A as high-risk deleterious SNPs., PMID:37286379
Pit 1 transporter (SLC20A1) as a key factor in the NPP1-mediated inhibition of insulin signaling in human podocytes., PMID:37269459
Identification of distinct immune infiltration and potential biomarkers in patients with liver ischemia-reperfusion injury., PMID:37105441
Modelling human lower urinary tract malformations in zebrafish., PMID:36977792
SLC20a1/PiT-1 is required for chorioallantoic placental morphogenesis., PMID:36795703
Cyclin B1 expression as an independent prognostic factor for lung adenocarcinoma and its potential pathways., PMID:36420081
Phosphate Metabolic Inhibition Contributes to Irradiation-Induced Myelosuppression through Dampening Hematopoietic Stem Cell Survival., PMID:36014901
Prognostic and therapeutic prediction by screening signature combinations from transcriptome-methylome interactions in oral squamous cell carcinoma., PMID:35794182
FAM111A is dispensable for electrolyte homeostasis in mice., PMID:35715480
High expression of SLC20A1 is less effective for endocrine therapy and predicts late recurrence in ER-positive breast cancer., PMID:35605014
Cellular abundance of sodium phosphate cotransporter SLC20A1/PiT1 and phosphate uptake are controlled post-transcriptionally by ESCRT., PMID:35447110
Long Noncoding RNA SLC20A1-1 Induces Nucleus Pulposus Apoptosis by Sponging miR-146a-5p., PMID:35349375
Effects of exogenous progesterone on the expression of mineral regulatory molecules by ovine endometrium and placentomes†., PMID:35191486
Renal Klotho and inorganic phosphate are extrinsic factors that antagonistically regulate hematopoietic stem cell maintenance., PMID:35172146
Hyperglycemic environment disrupts phosphate transporter function and promotes calcification processes in podocytes and isolated glomeruli., PMID:35150131
PDGF-BB is involved in phosphate regulation via the phosphate transporters in human neuroblastoma SH-SY5Y cells., PMID:35063775
Characteristics and therapeutic potential of sodium-dependent phosphate cotransporters in relation to idiopathic basal ganglia calcification., PMID:34924120
Circadian misalignment leads to changes in cortisol rhythms, blood biochemical variables and serum miRNA profiles., PMID:34130181
Adapter Protein RapGEF1 Is Required for ERK1/2 Signaling in Response to Elevated Phosphate in Vascular Smooth Muscle Cells., PMID:33951626
Identification of Prognosis-related Hub RNA Binding Proteins Function through Regulating Metabolic Processes in Tongue Cancer., PMID:33758601
The impact of type III sodium-dependent phosphate transporters (Pit 1 and Pit 2) on podocyte and kidney function., PMID:33738792
Novel mineral regulatory pathways in ovine pregnancy: I. phosphate, klotho signaling, and sodium-dependent phosphate transporters., PMID:33624764
High SLC20A1 Expression Is Associated With Poor Prognoses in Claudin-low and Basal-like Breast Cancers., PMID:33419798
Oxidative stress by Ca2+ overload is critical for phosphate-induced vascular calcification., PMID:33095057
Evidence of an intestinal phosphate transporter alternative to type IIb sodium-dependent phosphate transporter in rats with chronic kidney disease., PMID:32879980
Extracellular phosphate sensing in mammals: what do we know?, PMID:32755995
Genome-wide methylation association with current suicidal ideation in schizophrenia., PMID:32661777
Alveolar soft-part sarcoma (ASPS) resembles a mesenchymal stromal progenitor: evidence from meta-analysis of transcriptomic data., PMID:32596059
Intestinal epithelial ablation of Pit-2/Slc20a2 in mice leads to sustained elevation of vitamin D3 upon dietary restriction of phosphate., PMID:32564464
TDAG51 (T-Cell Death-Associated Gene 51) Is a Key Modulator of Vascular Calcification and Osteogenic Transdifferentiation of Arterial Smooth Muscle Cells., PMID:32434409
Interplay between primary familial brain calcification-associated SLC20A2 and XPR1 phosphate transporters requires inositol polyphosphates for control of cellular phosphate homeostasis., PMID:32393577
Slc20a1/Pit1 and Slc20a2/Pit2 are essential for normal skeletal myofiber function and survival., PMID:32080237
The Need of a Paradigm Shift to Better Understand PiT1 and PiT2 Biology: Response to "Why Is There No PiT1/SLC20A1 Pathogenic Variants Yet Linked to Primary Familial Brain Calcification?"., PMID:32049372
Why Is There No PiT1/SLC20A1 Pathogenic Variants Yet Linked to Primary Familial Brain Calcification?, PMID:32045498
Several phosphate transport processes are present in vascular smooth muscle cells., PMID:31886722
Tissue-Wide Gene Expression Analysis of Sodium/Phosphate Co-Transporters in Pigs., PMID:31717287
For research use only. Not for human or drug use.
