Catalog No.
YHC68301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu270-Glu318
Predicted molecular weight
18.10 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P0DMS8
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ADORA3, Adenosine receptor A3
Transduction of Lentiviral Vectors and ADORA3 in HEK293T Cells Modulated in Gene Expression and Alternative Splicing., PMID:40362672
Role of adenosine A3 receptor and endothelial nitric oxide synthase in patients with traumatic hemorrhagic shock., PMID:40198384
Adenosine Receptor 3 in Liver Cancer: Expression Variability, Epigenetic Modulation, and Enhanced Histone Deacetylase Inhibitor Effects., PMID:39911497
Nucleotide sequence variants, gene expression and serum profile of immune and antioxidant markers associated with brucellosis resistance/susceptibility in Shami goat., PMID:39825331
The association of gene polymorphisms of adenosine and dopamine receptors with the response to caffeine citrate treatment in infants with apnea of prematurity: a prospective nested case-control study., PMID:39468580
Electroacupuncture Relieves Neuropathic Pain via Adenosine 3 Receptor Activation in the Spinal Cord Dorsal Horn of Mice., PMID:39408573
Combining bioinformatics, network pharmacology and artificial intelligence to predict the target genes of S-ketamine for treating major depressive disorder., PMID:39118379
ADORA3 activation promotes goblet cell differentiation via enhancing HMGCS2-mediated ketogenesis in ulcerative colitis., PMID:39098229
Inhibition of ADORA3 promotes microglial phagocytosis and alleviates chronic ischemic white matter injury., PMID:38715283
Analgesic candidate adenosine A 3 receptors are expressed by perineuronal peripheral macrophages in human dorsal root ganglion and spinal cord microglia., PMID:38691673
Adenosine metabolic signature in circulating CD4+ T cells predicts remission in rheumatoid arthritis., PMID:38367982
Enhancing spinal cord stimulation-induced pain inhibition by augmenting endogenous adenosine signalling after nerve injury in rats., PMID:38310069
Therapeutic mechanism of baicalein in peritoneal dialysis-associated peritoneal fibrosis based on network pharmacology and experimental validation., PMID:37266145
The resurgence of the Adora2b receptor as an immunotherapeutic target in pancreatic cancer., PMID:37187740
The Heterogeneity of Tumour-Associated Macrophages Contributes to the Recurrence and Outcomes of Glioblastoma Patients., PMID:36542317
STAT1- and NFAT-independent amplification of purinoceptor function integrates cellular senescence with interleukin-6 production in preadipocytes., PMID:36321760
Identification of a six-gene prognostic signature for bladder cancer associated macrophage., PMID:36275756
Identification of early biomarkers of transcriptomics in alveolar macrophage for the prognosis of intubated ARDS patients., PMID:36056346
Development and verification of the nomogram for dilated cardiomyopathy gene diagnosis., PMID:35618744
Histomorphological changes and molecular mechanisms underlying the ameliorative effect of resveratrol on the liver of silver nanoparticles-exposed rats., PMID:35471163
Targeting the A3 adenosine receptor to prevent and reverse chemotherapy-induced neurotoxicities in mice., PMID:35093182
Tianma Formula Alleviates Dementia via ACER2-Mediated Sphingolipid Signaling Pathway Involving Aβ., PMID:35069753
Effects of Bacille Calmette Guerin (BCG) vaccination during COVID-19 infection., PMID:34624759
Neuroprotective Roles of the Adenosine A3 Receptor Agonist AST-004 in Mouse Model of Traumatic Brain Injury., PMID:34608616
Dysregulated long noncoding RNAs in the brainstem of the DBA/1 mouse model of SUDEP., PMID:34404356
Uncovering the Mechanisms of Adenosine Receptor-Mediated Pain Control: Focus on the A3 Receptor Subtype., PMID:34360719
Essential Genes and MiRNA-mRNA Network Contributing to the Pathogenesis of Idiopathic Pulmonary Arterial Hypertension., PMID:34026864
Adenosine A3 receptor activated in H2O2 oxidative stress of primary open-angle glaucoma., PMID:33987224
Pulsed-electromagnetic-field induced osteoblast differentiation requires activation of genes downstream of adenosine receptors A2A and A3., PMID:33630907
Adenosine A3 agonists reverse neuropathic pain via T cell-mediated production of IL-10., PMID:33621215
Identification of Potential Risk Genes and the Immune Landscape of Idiopathic Pulmonary Arterial Hypertension via Microarray Gene Expression Dataset Reanalysis., PMID:33478117
N6-methyladenosine (m6A) is an endogenous A3 adenosine receptor ligand., PMID:33472058
Increased expression of adenosine A3 receptor in tumor-infiltrating natural killer cells., PMID:33420353
Pharmacological characterisation of novel adenosine A3 receptor antagonists., PMID:33247159
The impact of single nucleotide polymorphisms in ADORA2A and ADORA3 genes on the early response to methotrexate and presence of therapy side effects in children with juvenile idiopathic arthritis: Results of a preliminary study., PMID:32969158
Adenosine A3 Receptor Mediates ERK1/2- and JNK-Dependent TNF-α Production in Toxoplasma gondii-Infected HTR8/SVneo Human Extravillous Trophoblast Cells., PMID:32871633
Targeting G Protein-Coupled Receptors with Magnetic Carbon Nanotubes: The Case of the A3 Adenosine Receptor., PMID:32706529
Analysis of association of ADORA2A and ADORA3 polymorphisms genotypes/haplotypes with efficacy and toxicity of methotrexate in patients with Rheumatoid arthritis., PMID:32448869
Assessment of biased agonism at the A3 adenosine receptor using β-arrestin and miniGαi recruitment assays., PMID:32224136
Activation of adenosine A3 receptor inhibits inflammatory cytokine production in colonic mucosa of patients with ulcerative colitis by down-regulating the nuclear factor-kappa B signaling., PMID:31714673
Design, Synthesis and Evaluation of New Indolylpyrimidylpiperazines for Gastrointestinal Cancer Therapy., PMID:31614517
Blockade of the Adenosine A3 Receptor Attenuates Caspase 1 Activation in Renal Tubule Epithelial Cells and Decreases Interleukins IL-1β and IL-18 in Diabetic Rats., PMID:31540220
Baseline adenosine receptor mRNA expression in blood as predictor of response to methotrexate therapy in patients with rheumatoid arthritis., PMID:31203399
ADORA2A Polymorphisms Influence Methotrexate Adverse Events in Rheumatoid Arthritis., PMID:31140226
Physiology and effects of nucleosides in mice lacking all four adenosine receptors., PMID:30822301
TLR-Induced IL-12 and CCL2 Production by Myeloid Cells Is Dependent on Adenosine A3 Receptor-Mediated Signaling., PMID:30804043
Ability of CP-532,903 to protect mouse hearts from ischemia/reperfusion injury is dependent on expression of A3 adenosine receptors in cardiomyoyctes., PMID:30710517
Extracellular adenosine promotes cell migration/invasion of Glioblastoma Stem-like Cells through A3 Adenosine Receptor activation under hypoxia., PMID:30660649
Modulation of blood inflammatory markers by benralizumab in patients with eosinophilic airway diseases., PMID:30658649
Comprehensive analysis of coexpressed long noncoding RNAs and genes in breast cancer., PMID:30362198
For research use only. Not for human or drug use.
