Catalog No.
YHC36302
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala2-Asp320
Predicted molecular weight
39.02 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P08758
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Endonexin II, ENX2, Placental anticoagulant protein 4, PP4, CBP-I, ANXA5, Anchorin CII, PAP-I, Thromboplastin inhibitor, Vascular anticoagulant-alpha, VAC-alpha, Calphobindin I, ANX5, Placental anticoagulant protein I, Annexin V, Annexin-5, Lipocortin V, Annexin A5
Development of Novel Annexin A5 Probes and a Fluorometric Microplate-Reader Method for High-Throughput Apoptosis Detection., PMID:40490949
Transcriptome and proteome profile analysis of the regulation of chicken ovarian development., PMID:40466268
Improved VPS4B O-GlcNAc modification triggers lipid droplets transferring from adipocytes to nasopharyngeal carcinoma cells., PMID:40410860
Identification of Potential Hub Proteins as Theragnostic Targets in Hepatocellular Carcinoma through Comprehensive Quantitative Tissue Proteomics Analysis., PMID:40375878
Annexin A5 controls VDAC1-dependent mitochondrial Ca2+ homeostasis and determines cellular susceptibility to apoptosis., PMID:40346273
ANXA5: related mechanisms of osteogenesis and additional biological functions., PMID:40342928
Synergistic mechanism of olaparib and cisplatin on breast cancer elucidated by network pharmacology., PMID:40295796
Exploring the mechanism of Bruceine D against cervical cancer by network pharmacology and the effect of Bruceine D on the EGFR pathway., PMID:40239560
Revealing the Mechanisms of Shikonin Against Diabetic Wounds: A Combined Network Pharmacology and In Vitro Investigation., PMID:40225010
Inhibition of PINK1 senses ROS signaling to facilitate neuroblastoma cell pyroptosis., PMID:40160153
Deciphering multifaceted molecular mechanisms of matairesinol in inhibiting triple-negative breast cancer through comprehensive systems biology investigations., PMID:40135676
S-hydroxychloroquine prevents the antiphospholipid thrombogenic complexes for antiphospholipid syndrome treatment., PMID:40120554
Global Profiling of Lactylation Proteomics and Specific Lactylated Site Validation in Rheumatoid Arthritis Patients., PMID:40112136
Structural insights into the fusion of annexin A5 and fluorescent proteins generating hundredfold differentiated binding affinities to phosphatidylserine., PMID:40100130
LAMP2-FLOT2 interaction enhances autophagosome-lysosome fusion to protect the septic heart in response to ILC2., PMID:40066518
Network pharmacology mechanism of Rosmarinus officinalis L.(Rosemary) to improve cell viability and reduces apoptosis in treating Alzheimer's disease., PMID:40055645
S100A12 triggers NETosis to aggravate myocardial infarction injury via the Annexin A5-calcium axis., PMID:39966386
Anti-fibroblast and anti-endothelial cell autoantibodies in pulmonary arterial hypertension (PAH) in patients with connective tissue diseases (CTD)., PMID:39918970
Immune infiltration landscape and potential drug-targeted implications for hepatocellular carcinoma with 'progression/hyper-progression' recurrence., PMID:39865865
SSL5-AnxA5 Fusion Protein Constructed Based on Human Atherosclerotic Plaque scRNA-Seq Data Preventing the Binding of Apoptotic Endothelial Cells, Platelets, and Inflammatory Cells., PMID:39857592
Calcium phosphate formation and deposition in ischemic neurons., PMID:39820937
Annexin A5 knockdown inhibits cardiomyocyte apoptosis and alleviates cardiac hypertrophy via activating the PI3K/AKT/Bcl-2 signaling pathway., PMID:39738388
Phosphatidylserine on sperm head interact with Annexin A5 on oviduct luminal cilia to form a sperm reservoir in pigs., PMID:39700614
Heterologous expression, purification and generation of specific antibodies for Annexin A8., PMID:39674528
A novel annexin dimer targets microglial phagocytosis of astrocytes to protect the brain-blood barrier after cerebral ischemia., PMID:39663418
Unveiling new protein biomarkers and therapeutic targets for acne through integrated analysis of human plasma proteomics and genomics., PMID:39493760
Bioinformatics data combined with single-cell analysis reveals patterns of immunoinflammatory infiltration and cell death in melanoma., PMID:39418727
Association of Anti-Annexin A5 Antibody With Pregnancy Outcomes: A Cohort Study: Anti-annexin A5 antibody with pregnancy outcomes., PMID:39381915
Comprehensive Proteomic Analysis of Dysferlinopathy Unveiling Molecular Mechanisms and Biomarkers Linked to Pathological Progression., PMID:39350328
Combining bioinformatics, network pharmacology, and artificial intelligence to predict the mechanism of resveratrol in the treatment of rheumatoid arthritis., PMID:39309832
Stage analysis of pancreatic ductal adenocarcinoma via network analysis., PMID:39308540
Molecular characterization, immunocorrelation analysis, WGCNA analysis and machine learning modeling of genes associated with copper death subtypes of laryngeal cancer., PMID:39302398
Exploring the Effects and Potential Mechanisms of Hesperidin for the Treatment of CPT-11-Induced Diarrhea: Network Pharmacology, Molecular Docking, and Experimental Validation., PMID:39273257
Modulation of Annexin-Induced Membrane Curvature by Cholesterol and the Anionic Lipid Headgroup during Plasma Membrane Repair., PMID:39214593
Network pharmacology and experimental validation to reveal the pharmacological mechanisms of Astragaloside Ⅳ in treating intervertebral disc degeneration., PMID:39214272
ANXA5 predicts prognosis and immune response and mediates proliferation and migration in head and neck squamous cell carcinoma., PMID:39168258
Identifying the key hub genes linked with lung squamous cell carcinoma by examining the differentially expressed and survival genes., PMID:39097557
Differential inflammatory conditioning of the bone marrow by acute myeloid leukemia and its impact on progression., PMID:38996202
Annexin A5 is a novel prognostic biomarker in oral squamous cell carcinoma., PMID:38945807
Postbiotic-based recombinant receptor activator of NF-κB ligand enhanced oral vaccine efficiency in chicken., PMID:38922350
Annexin A5 Derived from Cell-free Fat Extract Attenuates Osteoarthritis via Macrophage Regulation., PMID:38904008
Exposure to thiourea during the early stages of development impedes the formation of the swim bladder in zebrafish larvae., PMID:38888127
The different roles of V-ATPase a subunits in phagocytosis/endocytosis and autophagy., PMID:38873931
ANXA5: A Key Regulator of Immune Cell Infiltration in Hepatocellular Carcinoma., PMID:38824386
Combined Effects of Annexin A5 Overexpression, 5-Fluorouracil Treatment, and Irradiation on Cell Viability of Caski Cervical Cancer Cell Line., PMID:38811453
New insights into the hypothalamic-pituitary-thyroid axis: a transcriptome- and proteome-wide association study., PMID:38805593
Exploring the Mechanism of Cardiorenal Protection with Finerenone Based on Network Pharmacology., PMID:38801815
Annexin-A5 monomer as a membrane repair agent for the treatment of renal ischemia-reperfusion injury., PMID:38796668
Immunogenic Treatment of Metastatic Breast Cancer Using Targeted Carbon Nanotube Mediated Photothermal Therapy in Combination with Anti-Programmed Cell Death Protein-1., PMID:38772718
Elucidating the molecular mechanisms of pterostilbene against cervical cancer through an integrated bioinformatics and network pharmacology approach., PMID:38761877