Catalog No.
YHC03202
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Tyr184
Predicted molecular weight
22.07 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P03372
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Estrogen receptor, ER-alpha, ESR, ER, ESR1, Nuclear receptor subfamily 3 group A member 1, NR3A1, Estradiol receptor
Estrogen receptor alpha dynamics and plasticity during endocrine resistance., PMID:40514718
A network toxicology approach to decipher paraben-induced molecular dysregulation in breast cancer pathogenesis., PMID:40512387
Identification and validation of cellular senescence-related genes and immune cell infiltration characteristics in intervertebral disc degeneration., PMID:40510349
Mechanism of Ginsenosides in the Treatment of Diabetes Mellitus Based on Network Pharmacology and Molecular Docking., PMID:40508108
Elucidating the Anti-Diabetic Mechanisms of Mushroom Chaga (Inonotus obliquus) by Integrating LC-MS, Network Pharmacology, Molecular Docking, and Bioinformatics., PMID:40508014
Role of Estrogen Signaling in Notch Pathway Activation in Sertoli Cells., PMID:40506655
Integrating metabolomics and network pharmacology analysis provides new insights into the lipid metabolism disorder of Abrus mollis., PMID:40505757
Anti-Osteoporosis Activity of Lycopene Through ESR1: Network Pharmacology, Molecular Docking, Imaging Technology, and Experimental Validation., PMID:40504801
DNA methylation patterns in breast cancer, paired benign tissue from ipsilateral and contralateral breast, and healthy controls., PMID:40500734
Dynamic VOC fingerprinting and mechanistic exploration of medicinal edible fungus Inonotus hispidus: A combination of HS-GC-IMS/MS multivariate analysis and network-based pharmacology., PMID:40499502
Noninvasive markers for warning premature ovarian insufficiency: a Mendelian randomisation study., PMID:40495196
Network pharmacology and molecular docking-based characterization of the mechanisms through which Astragali Radix-Atractylodes macrocephala Koidz herb pair can treat membranous nephropathy., PMID:40489804
Unveiling pharmacological targets of Rihimaside C for radiation-induced lung injury: An in silico and experimental integrated approach., PMID:40486275
Unveiling the mechanisms of Tianjihuang in hepatocellular carcinoma: a network pharmacology and molecular docking study., PMID:40478357
Metabolomics combined with network pharmacology reveals the anti-hepatoma effects of terpenoids from Polygonatum kingianum var. grandifolium and Polygonatum sibiricum Redouté as well as differences in their terpenoid metabolites., PMID:40474061
Computational and Molecular Profiling of the Anticancer Properties of Thuja occidentalis L. From Southern Punjab., PMID:40468803
Daidzein alleviates ethanol-induced acute gastric injury in rats by targeting ESR1 and activating the PI3K/AKT/CREB signaling pathway., PMID:40466503
PML1-Mediated Feedforward Loop Through PI3K and MAPK Axes Drives Endocrine Resistance., PMID:40463196
Integrated multi-omics analysis identifies TLR4-mediated mechanisms in ATBC-induced ovarian dysfunction and female infertility: A network toxicology, transcriptomic, and Mendelian randomization study., PMID:40462131
Harnessing miRNA dynamics in HIV-1-infected macrophages: Unveiling new targeted therapeutics using systems biology., PMID:40453371
MitoQ for vitiligo by mitigating PARP1 translocation aberrations: Network pharmacology and experimental validation., PMID:40451398
LSD1 engaged ERα activation orchestrates the formation of migrasomes to promote gastric cancer metastasis., PMID:40449770
Systematic Exploration of Potential Toxicity Targets and Molecular Mechanisms of Emerging Short-Chain PFAS Substitutes: PFBA- and PFBS-Induced Hepatocellular Carcinoma Based on Toxicity Network Analysis, Machine Learning, and Biomimetic Calculations., PMID:40448290
Computer-aided unveiling molecular mechanisms of Xylocarpus granatum against colorectal cancer: therapeutic intervention targeting P13K-AKT signaling pathway., PMID:40446548
Computational investigation and experimental validation of the molecular mechanism of Solanecio mannii aqueous roots extract against cervical cancer., PMID:40446016
Wogonin inhibits the proliferation of prolactinoma through the PI3K/AKT signaling pathway., PMID:40444042
EFHD1 promotes breast cancer progression through estrogen signaling., PMID:40441345
Evaluation and Correlation of 17β-Estradiol in Blood and Estrogen Receptor α (ERα) and Estrogen Receptor β(ER β) in Tissue of Oral Squamous Cell Carcinoma., PMID:40439386
Therapeutic role of Crateva religiosa in diabetic nephropathy: Insights into key signaling pathways., PMID:40435181
Investigating the Mechanisms of Lycii fructus in Treating Nonalcoholic Fatty Liver Disease and Diabetes Comorbidity Through Network Pharmacology and Molecular Dynamics., PMID:40433113
Ovarian Cancer-Epidemiology, Classification, Pathogenesis, Treatment, and Estrogen Receptors' Molecular Backgrounds., PMID:40429755
Integrative in silico and in vivo Drosophila model studies reveal the anti-inflammatory, antioxidant, and anticancer properties of red radish microgreen extract., PMID:40425671
Targeted Knockdown of Epithelial Estrogen Receptor α to Mitigate Ferroptosis and Epithelial-Mesenchymal Transition in Eosinophilic Asthma., PMID:40424612
17β-Estradiol Promotes Tumorigenicity Through an Autocrine AREG/EGFR Loop in ER-α-Positive Breast Cancer Cells., PMID:40422206
Exploring the mechanisms and targets of proton pump inhibitors-induced osteoporosis through network toxicology, molecular docking, and molecular dynamics simulations., PMID:40421218
Maternal cafeteria diet adversely affects the reproductive parameters of rat offspring in a sex-specific manner., PMID:40420282
A miR-770-5p/XBP1-driven pathway controls ESR1 expression and tamoxifen response in luminal breast cancer., PMID:40407833
Investigation of Fructus sophorae extract's therapeutic mechanism in atrophic vaginitis based on network pharmacology and experimental validation., PMID:40406491
Estrogen signaling in the ventromedial hypothalamus is required for the development of aggression circuitry in male mice., PMID:40403719
IL-8 and ER-α gene polymorphisms as potential risk factors for leiomyoma., PMID:40393185
Exploring Hidden Dangers: Predicting Mycotoxin-like Toxicity and Mapping Toxicological Networks in Hepatocellular Carcinoma., PMID:40393043
Enhancing ERα-targeted compound efficacy in breast cancer threapy with ExplainableAI and GeneticAlgorithm., PMID:40392928
LncRNA NEAT1 participates in diminished ovarian reserve by affecting granulosa cell apoptosis and estradiol synthesis via the miR-204-5p/ESR1 axis., PMID:40380255
Engineering ERα degraders with pleiotropic ubiquitin ligase ligands maximizes therapeutic efficacy by co-opting distinct effector ligases., PMID:40378821
An Analysis of Effective Components of Pulsatillae radix Using UHPLC-QTOF-MS/MS and Network Pharmacology to Investigate its Effects on Ulcerative Colitis., PMID:40375698
ESR1 testing on FFPE samples from metastatic lesions in HR + /HER2- breast cancer after progression on CDK4/6 inhibitor therapy., PMID:40369610
Transcriptome analysis reveals key genes and signalling pathways related to residual feed intake in meat-type ducks., PMID:40367888
ESR1 overexpression is a biomarker of relapse and worse prognosis in stage I endometrioid endometrial carcinoma., PMID:40367016
Discovery and Characterization of PVTX-321 as a Potent and Orally Bioavailable Estrogen Receptor Degrader for ER+/HER2- Breast Cancer., PMID:40366756
6PPD and 6PPD Quinone Induce Endometrial Cell Dysfunction via Activating ERα and GPER at Human-Relevant Levels., PMID:40364734
For research use only. Not for human or drug use.
