Catalog No.
YHN14701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg23-Pro292
Predicted molecular weight
33.64 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q95460
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Class I histocompatibility antigen-like protein, MR1, MHC class I-related gene protein, Major histocompatibility complex class I-related gene protein
Mutations outside the MR1 antigen binding groove differentially inhibit presentation of exogenous antigens., PMID:40475583
Periplasmic Protein Mobility for Extracellular Electron Transport in Shewanella oneidensis., PMID:40431315
Sotatercept: A Crosstalk Between Pathways and Activities in the Pulmonary Circulation and Blood., PMID:40429991
Genomic and transcriptomic insights into vertebrate host-specific Lactobacillus johnsonii adaptation in the gastrointestinal tract., PMID:40358235
Mitochondria regulate MR1 protein expression and produce self-metabolites that activate MR1-restricted T cells., PMID:40354545
Molecular Insights Into MR1-Mediated T Cell Immunity: Lessons Learned and Unanswered Questions., PMID:40338831
Light-regulated dentification and dissimilatory nitrate reduction by nano-bio electric syntrophic consortium., PMID:40334323
Rational Design of Methylene Blue-Raloxifene Conjugates for Efficient Breast Tumor Elimination Triggered by ERα Degradation., PMID:40213902
Molecular basis underpinning MR1 allomorph recognition by an MR1-restricted T cell receptor., PMID:40207221
Redox disruption using electroactive liposome coated gold nanoparticles for cancer therapy., PMID:40188189
Insights into the Direct Photoelectron Transfer Mechanism in Cofactor-free Redox Carbon Dots and Cytochrome c Nitrite Reductase Biohybrids Responsible for Ammonia Synthesis., PMID:40153603
Long-Term Phenotypic Evolution in GRIN2A-Related Disorders: Electroclinical and Genetic Insights from Two Families with Extended Follow-Up., PMID:40149474
Herpes simplex virus type 1 impairs mucosal-associated invariant T cells., PMID:40135871
MAIT Cells Promote Cholesterol Excretion Pathways Mitigating Atherosclerosis., PMID:40135347
Dynamic synthesis and transport of phenazine-1-carboxylic acid to boost extracellular electron transfer rate., PMID:40128539
MAIT cell deficiency exacerbates neuroinflammation in P301S human tau transgenic mice., PMID:40114233
Mucosal-associated invariant T-cells in pulmonary pathophysiology., PMID:40104908
Opportunities and challenges for the use of human samples in translational cardiovascular research: a scientific statement of the ESC Working Group on Cellular Biology of the Heart, the ESC Working Group on Cardiovascular Surgery, the ESC Council on Basic Cardiovascular Science, the ESC Scientists of Tomorrow, the European Association of Percutaneous Cardiovascular Interventions of the ESC, and the Heart Failure Association of the ESC., PMID:40084813
Recognition of MR1-antigen complexes by TCR Vγ9Vδ2., PMID:40040716
Deep characterization of females with heterozygous Duchenne muscular dystrophy mutations., PMID:40035839
Biological functions and therapeutic applications of human mucosal-associated invariant T cells., PMID:40025566
Defenders or defectors: mucosal-associated invariant T cells in autoimmune diseases., PMID:40020256
Omics data integration analysis identified new biological insights into chronic antibody-mediated rejection (CAMR)., PMID:39979925
Myofibrillogenesis Regulator-1 in Smooth Muscle Cells Modulates Inflammation Signaling Pathways via Regulating ROCK1 Ubiquitination and Degradation to Impact Aortic Dissection., PMID:39931165
Human MAIT cell response profiles biased toward IL-17 or IL-10 are distinct effector states directed by the cytokine milieu., PMID:39903121
A universal and wide-range cytosine base editor via domain-inlaid and fidelity-optimized CRISPR-FrCas9., PMID:39893181
Mucosal-Associated Invariant T (MAIT) Cell-Mediated Immune Mechanisms of Peritoneal Dialysis-Induced Peritoneal Fibrosis and Therapeutic Targeting., PMID:39874111
α-N-Methyltransferase regiospecificity is mediated by proximal, redundant enzyme-substrate interactions., PMID:39840790
Sotatercept in pulmonary hypertension and beyond., PMID:39825683
Cigarette smoke components modulate the MR1-MAIT axis., PMID:39820322
MAIT cell deficiency exacerbates neuroinflammation in P301S human tau transgenic mice., PMID:39803476
Frontal lobe intra-axial schwannoma harboring a CHD7::VGLL3 fusion and heterozygous TSC2 p.F1510del mutation in a young child., PMID:39792305
The MR1/MAIT cell axis enhances dystrophic neurite development in Alzheimer's disease., PMID:39777865
A specific and adaptable approach to track CD206+ macrophages by molecular MRI and fluorescence imaging., PMID:39776805
In-Depth Phenotyping of PIGW-Related Disease and Its Role in 17q12 Genomic Disorder., PMID:39766333
Two FAM134B isoforms differentially regulate ER dynamics during myogenesis., PMID:39762646
MHC-related protein 1-restricted recognition of cancer via a semi-invariant TCR-α chain., PMID:39744940
Myeloid antigen-presenting cells in neurodegenerative diseases: a focus on classical and non-classical MHC molecules., PMID:39720231
Report of the Italian Cohort with Activated Phosphoinositide 3-Kinase δ Syndrome in the Target Therapy Era., PMID:39714594
Expansion of the Phenotype of You-Hoover-Fong Syndrome and Possible Increased Risk of Cancer., PMID:39704248
The carbonyl nucleobase adduct M3Ade is a potent antigen for adaptive polyclonal MR1-restricted T cells., PMID:39701104
Acute hypoxia stress mediates HIF-1α-Yki-Cactus axis to facilitate the infection of Vibrio parahaemolyticus in Litopenaeus vannamei., PMID:39664389
Enhanced chloramphenicol biodegradation and sustainable electricity generation via co-cultured electroactive biofilms modified with in-situ self-assembled gold nanoparticles and reduced graphene oxide., PMID:39662439
Semiartificial Photosynthetic Nanoreactors for H2 Generation., PMID:39626075
Measurements of neurite extension and nucleokinesis in an iPSC-derived model system following microtubule perturbation., PMID:39602292
Constitutive opening of the Kv7.2 pore activation gate causes KCNQ2-developmental encephalopathy., PMID:39602259
MR1 presents vitamin B6-related compounds for recognition by MR1-reactive T cells., PMID:39589872
A WFS1 variant disrupting acceptor splice site uncovers the impact of alternative splicing on beta cell apoptosis in a patient with Wolfram syndrome., PMID:39520565
The Role of Exogenous microRNAs on Human Health: The Plant-Human Trans-Kingdom Hypothesis., PMID:39519491
Perspectives on Sotatercept in Pulmonary Arterial Hypertension., PMID:39518603
For research use only. Not for human or drug use.
