Catalog No.
YHF65401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser2-Thr416
Predicted molecular weight
48.49 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P78356
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
1-phosphatidylinositol 5-phosphate 4-kinase 2-beta, Phosphatidylinositol 5-phosphate 4-kinase type-2 beta, PtdIns(5)P-4-kinase isoform 2-beta, Phosphatidylinositol 5-phosphate 4-kinase type II beta, PIP4KII-beta, Diphosphoinositide kinase 2-beta, PI(5)P 4-kinase type II beta, PIP5K2B, PIP4K2B
Potency and efficacy of pharmacological PIP4K2 inhibitors in acute lymphoblastic leukemia., PMID:38851560
PIP4K2B Protein Regulation by NSD1 in HPV-Negative Head and Neck Squamous Cell Carcinoma., PMID:38539515
Pharmacological Inhibition of PIP4K2 Potentiates Venetoclax-Induced Apoptosis in Acute Myeloid Leukemia., PMID:38069220
Autoantibodies against PIP4K2B and AKT3 Are Associated with Skin and Lung Fibrosis in Patients with Systemic Sclerosis., PMID:36982700
PIP4K2B is mechanoresponsive and controls heterochromatin-driven nuclear softening through UHRF1., PMID:36918565
PIP5K1C phosphoinositide kinase deficiency distinguishes PIKFYVE-dependent cancer cells from non-malignant cells., PMID:36803256
Bacterial-Type Long-Chain Polyphosphates Bind Human Proteins in the Phosphatidylinositol Signaling Pathway., PMID:35909349
Identification of Metabolic-Associated Genes for the Prediction of Colon and Rectal Adenocarcinoma., PMID:33833525
High-throughput proteomics of breast cancer interstitial fluid: identification of tumor subtype-specific serologically relevant biomarkers., PMID:33176066
Distribution and localization of phosphatidylinositol 5-phosphate, 4-kinase alpha and beta in the brain., PMID:32449185
PIP4K2A and PIP4K2C transcript levels are associated with cytogenetic risk and survival outcomes in acute myeloid leukemia., PMID:31109595
PIP4Ks Suppress Insulin Signaling through a Catalytic-Independent Mechanism., PMID:31091439
The response to neoadjuvant chemoradiotherapy with 5-fluorouracil in locally advanced rectal cancer patients: a predictive proteomic signature., PMID:29681787
The correlation analysis of miRNAs and target genes in metastasis of cervical squamous cell carcinoma., PMID:29343084
MANF regulates hypothalamic control of food intake and body weight., PMID:28924165
PIP4K2B: Coupling GTP Sensing to PtdIns5P Levels to Regulate Tumorigenesis., PMID:27132569
Gene expression profiling analysis of lung adenocarcinoma., PMID:26840709
The basal transcription complex component TAF3 transduces changes in nuclear phosphoinositides into transcriptional output., PMID:25866244
PIP4K and the role of nuclear phosphoinositides in tumour suppression., PMID:25728392
Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumors., PMID:24209622
Low PIP4K2B expression in human breast tumors correlates with reduced patient survival: A role for PIP4K2B in the regulation of E-cadherin expression., PMID:24127122
For research use only. Not for human or drug use.
