Catalog No.
MHC65503
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Immunogen
E. coli - derived recombinant Human SAA1 (Ser20-Tyr122).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:2000-1:8000
Target
SAA,Serum amyloid A-1 protein,SAA1,Amyloid fibril protein AA,
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P0DJI8
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
1A081
Target complement factor H / serum amyloid a signaling in trichloroethylene-induced immune kidney injury., PMID:40373713
Sequential transcriptome profiling: comparative analysis of normal and canine lymphoma preceding detailed T-cell and B-cell subtype comparison., PMID:39911484
The Clinical and Molecular Response of Pyoderma Gangrenosum to IL-23 Blockade: Result from a Proof-of-Concept Open-Label Clinical Trial., PMID:39547392
Extracellular vesicles bearing serum amyloid A1 exacerbate neuroinflammation after intracerebral haemorrhage., PMID:39357895
Serum amyloid A1 induced dysfunction of airway macrophages via CD36 pathway in allergic airway inflammation., PMID:39244902
Naïve Inflammatory Proteome Profiles of Glucocorticoid Responsive Polymyalgia Rheumatica and Rheumatic Arthritis Patients-Links to Triggers and Proteomic Manifestations., PMID:38793033
Improvement of high-density lipoprotein atheroprotective properties in patients with systemic lupus erythematosus after belimumab treatment., PMID:38514392
A Lipopolysaccharide-Enriched Cow's Milk Allergy Microbiome Promotes a TLR4-Dependent Proinflammatory Intestinal Immune Response., PMID:38169331
Proteomic profiling identifies SPP1 associated with rapidly progressive interstitial lung disease in anti-MDA5-positive dermatomyositis., PMID:38167532
Lactobacillus Intestinalis Primes Epithelial Cells to Suppress Colitis-Related Th17 Response by Host-Microbe Retinoic Acid Biosynthesis., PMID:37983567
Impairment of aryl hydrocarbon receptor signalling promotes hepatic disorders in cancer cachexia., PMID:37127348
Neutralizing serum amyloid a protects against sinusoidal endothelial cell damage and platelet aggregation during acetaminophen-induced liver injury., PMID:36463757
Universal DNAzyme walkers-triggered CRISPR-Cas12a/Cas13a bioassay for the synchronous detection of two exosomal proteins and its application in intelligent diagnosis of cancer., PMID:36308835
iTRAQ-based proteomic analysis of differentially expressed proteins in sera of seronegative and seropositive rheumatoid arthritis patients., PMID:34812532
A mutation in the SAA1 promoter causes hereditary amyloid A amyloidosis., PMID:34560138
High-resolution serum proteome trajectories in COVID-19 reveal patient-specific seroconversion., PMID:34232570
Discovery of plasma biomarkers with data-independent acquisition mass spectrometry and antibody microarray for diagnosis and risk stratification of pulmonary embolism., PMID:33825327
Elevated Serum Amyloid a Levels Are not Specific for Sarcoidosis but Associate with a Fibrotic Pulmonary Phenotype., PMID:33799927
Blood serum amyloid A as potential biomarker of pembrolizumab efficacy for patients affected by advanced non-small cell lung cancer overexpressing PD-L1: results of the exploratory "FoRECATT" study., PMID:33231726
Targeted mass spectrometry for Serum Amyloid A (SAA) isoform profiling in sequential blood samples from experimentally Staphylococcus aureus infected pigs., PMID:32702520
Differential expression of serum amyloid A1 and A3 in bovine epithelia., PMID:32378645
Recent developments in the field of cachexia, sarcopenia, and muscle wasting: highlights from the 12th Cachexia Conference., PMID:32049447
Plasma proteomic analysis of autoimmune hepatitis in an improved AIH mouse model., PMID:31906950
Serum amyloid A exhibits pH dependent antibacterial action and contributes to host defense against Staphylococcus aureus cutaneous infection., PMID:31819008
Development and Validation of a Test to Monitor Endoscopic Activity in Patients With Crohn's Disease Based on Serum Levels of Proteins., PMID:31711925
Neutralizing effects of anti-infliximab antibodies on synergistically-stimulated human coronary artery endothelial cells., PMID:31629987
Cancer-Derived VEGF-C Increases Chemokine Production in Lymphatic Endothelial Cells to Promote CXCR2-Dependent Cancer Invasion and MDSC Recruitment., PMID:31390756
Multiplex Assay for Quantification of Acute Phase Proteins and Immunoglobulin A in Dried Blood Spots., PMID:30408962
Time-resolved fluorescent immunoassay-based combined detection of procalcitonin, C-reactive protein, heparin binding protein, and serum amyloid A1 to improve the diagnostic accuracy of early infection., PMID:30338547
AA amyloidosis - Benefits and prospects of IL-6 inhibitors., PMID:30132351
Response Predictors to Calcineurin Inhibitors in Patients with Primary Membranous Nephropathy., PMID:29698936
Naturally occurring antibodies against serum amyloid A reduce IL-6 release from peripheral blood mononuclear cells., PMID:29617422
Serum amyloid A1 (SAA1) protein in human colostrum., PMID:29511620
Lipoprotein apheresis affects lipoprotein particle subclasses more efficiently compared to the PCSK9 inhibitor evolocumab, a pilot study., PMID:29398508
Short communication: Supplementation of colostrum and milk with 5-hydroxy-l-tryptophan affects immune factors but not growth performance in newborn calves., PMID:29102139
Selection and validation of antibody clones against IgG and IgA subclasses in switched memory B-cells and plasma cells., PMID:28965920
Suppression of Lipopolysaccharide-Induced Inflammatory Response by Fragments from Serum Amyloid A., PMID:28674180
Easy-to-Fabricate and High-Sensitivity LSPR Type Specific Protein Detection Sensor Using AAO Nano-Pore Size Control., PMID:28406469
Plasma cytokine profiling to predict susceptibility to acute mountain sickness., PMID:28396299
Scavenger Receptor A1 Prevents Metastasis of Non-Small Cell Lung Cancer via Suppression of Macrophage Serum Amyloid A1., PMID:28202524
Serum Amyloid A Stimulates PKR Expression and HMGB1 Release Possibly through TLR4/RAGE Receptors., PMID:26052716
Human serum amyloid A3 (SAA3) protein, expressed as a fusion protein with SAA2, binds the oxidized low density lipoprotein receptor., PMID:25738827
Serum amyloid A chemoattracts immature dendritic cells and indirectly provokes monocyte chemotaxis by induction of cooperating CC and CXC chemokines., PMID:25345597
Calcitonin gene-related peptide upregulates serum amyloid A synthesis through activation of interleukin-6., PMID:24096654
High-density lipoprotein profiling changes in patients with rheumatoid arthritis treated with tumor necrosis factor inhibitors: a cohort study., PMID:23637327
Homocysteine induces serum amyloid A3 in osteoblasts via unlocking RGD-motifs in collagen., PMID:23085993
Effectiveness of etanercept vs cyclophosphamide as treatment for patients with amyloid A amyloidosis secondary to rheumatoid arthritis., PMID:22879465
Large-scale isotype-specific quantification of Serum amyloid A 1/2 by multiple reaction monitoring in crude sera., PMID:22300576
A distinct microvascular endothelial gene expression profile in severe IUGR placentas., PMID:22264586
Testosterone response of hepatic gene expression in female mice having acquired testosterone-unresponsive immunity to Plasmodium chabaudi malaria., PMID:21669218