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Research Grade Anti-Human CD133/PROM1 & CD3E Bispecific Antibody (MS133)

Catalog #:   DHA68402 Specific References (50) DATASHEET
Host species: Human
Isotype: IgG
Applications: Research Grade Biosimilar
Expression system: Mammalian Cells
Overview

Catalog No.

DHA68402

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG

Clonality

Monoclonal

Target

PROML1, PROM1, Prominin-1, Antigen AC133, CD133, Prominin-like protein 1, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O43490 & P07766

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

Bispecific

Clone ID

MS133

Data Image
References

Fenbendazole Exhibits Antitumor Activity Against Cervical Cancer Through Dual Targeting of Cancer Cells and Cancer Stem Cells: Evidence from In Vitro and In Vivo Models., PMID:40509264

IGF1/IGF1R signaling promotes the expansion of liver CSCs and serves as a potential therapeutic target in HCC., PMID:40500564

Impact of trifluoromethyl Ugi adducts as anticancer agents: EGFR inhibition, apoptosis induction and miRNA up-regulation., PMID:40496375

Erianin inhibits the proliferation and stemness of pancreatic cancer cells by interacting with MEK1/2., PMID:40484042

161Tb-Based Anti-L1CAM Radioimmunotherapy Shows Superior Efficacy in Eliminating Ovarian Cancer Stem Cells Compared with 177Lu in Preclinical Models of Ovarian Cancer., PMID:40473465

Co-expression of Stem Cell Markers CD133 and CD44 as Predictors of Metastatic Potential of Colorectal Carcinoma., PMID:40452184

Optimizing single cell RNA sequencing of stem cells. A streamlined workflow for enhanced sensitivity and reproducibility in hematopoietic studies. The use of human umbilical cord blood-derived hematopoietic stem and progenitor cells., PMID:40443736

Is There Any Difference in Stem Cell Population between Type I and Type II Endometrial Cancer? A Pilot Study., PMID:40433700

CD133 Expression in Circulating Tumor Cells as a Prognostic Marker in Colorectal Cancer., PMID:40429879

ASO Visual Abstract: Risk of Recurrence and Cancer Stem Cell Marker CD133 Expression Varies in Males Versus Females With Papillary Thyroid Cancer., PMID:40419712

Therapeutic potential of bone marrow-derived very small embryonic-like stem cells followed by thrombin-activated platelet-rich plasma for endometrial regeneration., PMID:40418982

Curzerene suppresses epithelial-mesenchymal transition in gastric precancerous lesion cells through targeted regulation of YAP via the long non-coding RNA AFAP1-AS1., PMID:40414046

The combined application of cis-cyclo(L-Phe-L-Pro) with antimicrobial proline-based 2,5-diketopiperazines significantly enhances anti-breast cancer activity by selectively targeting cancer stem cells., PMID:40409392

Targeted Radionuclide Therapy Using a Lutetium-177 Labeled Human Anti-CD133 Antibody., PMID:40405046

Propranolol accelerates adipogenesis and inhibits endothelium differentiation of HemSCs via suppressing HK2 mediated glycolysis., PMID:40382470

Delta 4-desaturase sphingolipid 2 enhances prostate cancer stem-like traits through phytoceramide-mediated PI3K-AKT signaling pathway., PMID:40380873

Pentagalloyl glucose targets the JAK1/JAK3-STAT3 pathway to inhibit cancer stem cells and epithelial-mesenchymal transition in 5-fluorouracil-resistant colorectal cancer., PMID:40378534

Detection of circulating tumor cells that predicts the efficacy of neoadjuvant chemotherapy for locally advanced triple-negative breast cancer., PMID:40370743

Recurring cycles of deprivation of serum and migration in confined spaces augments ganglioside SSEA-4 expression, boosting clonogenicity and cisplatin resistance in TNBC cell line., PMID:40369257

Chronic arsenic exposure of ovarian surface and fallopian tube cultures induces giant and/or multinucleated cells with phagocytosis-like properties and an inflammatory phenotype., PMID:40368219

Lomibuvir sensitizes radioiodine-resistant thyroid cancer cell lines to radioiodine treatment by targeting hTERT RNA-dependent polymerase activity., PMID:40358852

Urinary Extracellular Vesicle Analysis Reveals Early Signs of Kidney Inflammation and Damage in Single Ventricle Paediatric Patients After Fontan Operation., PMID:40356857

Protein tyrosine phosphatase receptor type kappa (PTPRK) revisited: evolving insights into structure, function, and pathology., PMID:40355891

Circulating Endothelial Progenitor Cells and Metabolic Factors in Childhood Cancer Survivors., PMID:40350548

Characterization and targeting of chemoresistant triple-negative breast cancer subtypes using amino-pyridine compounds., PMID:40350044

17beta-estradiol (E2) Regulates Malignancies and Stemness in Endometrial Carcinoma (EC) via Interacting with ESR1., PMID:40342082

Deciphering the "Rosetta Stone" of ovarian cancer stem cells: Opportunities and challenges., PMID:40339667

(-)-Epicatechin regulates the resistance of lung adenocarcinoma cells to radiotherapy through the downregulation of FOXM1., PMID:40335843

Diagnostic Potential of CD44, CD133, and VDR in Epithelial Ovarian Tumors: Association with Histopathology Parameters., PMID:40332380

Quantification of Urine and Plasma Levels of Extracellular Vesicles in a Cohort of Kidney Transplant Recipients and Chronic Kidney Disease Patients., PMID:40332150

Modulating Cancer Stem Cell Characteristics in CD133+ Melanoma Cells through Hif1α, KLF4, and SHH Silencing., PMID:40321496

CD133-positive dermal papilla cells are a major driver in promoting hair follicle formation., PMID:40313747

GENETIC ALTERATIONS IN TUBO-OVARIAN EPITHELIUM DURING OVARIAN NEOPLASIA., PMID:40305800

Epigenetic Regulation of Dental Follicle Stem Cells in Odontogenic Regeneration., PMID:40296331

Substituents introduction of methyl and methoxy functional groups on resveratrol stabilizes mTOR binding for autophagic cell death induction., PMID:40287470

Mannose modified graphene oxide drug-delivery system targets cancer stem cells and tumor-associated macrophages to promote immunotherapeutic efficacy., PMID:40286606

Unveiling the impact of CD133 and CD105 in MDA-MB-231 cell-derived exosomes on breast cancer cell signaling pathways., PMID:40285779

Liraglutide improves peripheral perfusion and markers of angiogenesis and inflammation in people with type 2 diabetes and peripheral artery disease: An 18-month follow-up of a randomized clinical trial., PMID:40276845

Expression of innate immunity genes in human hematopoietic stem/progenitor cells - single cell RNA-seq analysis., PMID:40264766

Asherman syndrome at single-cell resolution., PMID:40253078

Molecular and phenotypic characterization of 5-FU resistant colorectal cancer cells: toward enrichment of cancer stem cells., PMID:40251609

Impact of enzymatic isolation on the propagation efficiency of patient-derived colorectal cancer organoids., PMID:40251201

ARID3A inhibits colorectal cancer cell stemness and drug-resistance by targeting a multitude of stemness-associated genes., PMID:40250751

Patient-Derived Colorectal Cancer Extracellular Matrices Modulate Cancer Cell Stemness Markers., PMID:40243470

7‑Difluoromethoxyl‑5,4'‑di‑n‑octylygenistein targets the STAT3 pathway by upregulating microRNA‑152‑3p expression to inhibit self‑renewal and tumor growth in non‑small cell lung carcinoma., PMID:40242966

Renal ischemia alters the mRNA and miRNA profile of vasculature-related genes in scattered tubular-like cells from female pigs., PMID:40241609

Risk of Recurrence and Cancer Stem Cell Marker CD133 Expression Vary in Males Versus Females with Papillary Thyroid Cancer., PMID:40214912

Renal Ischemia Induces Endoplasmic Reticulum Stress and Impairs the Reparative Potency of Scattered Tubular-Like Cells., PMID:40209698

Rapid Isolation and Characterization of Exosomes through a Single-Step, Label-Free Protein Biomarker Analysis., PMID:40203051

Photothermal treatment of prostate tumor with micellar indocyanine green and napabucasin to co-ablate cancer cells and cancer stem cells., PMID:40194599

Datasheet
$ 484
Product specifications
100 μg 484 1 mg 1932

Contact Information

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Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

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Research Grade Anti-Human CD133/PROM1 & CD3E Bispecific Antibody (MS133) [DHA68402]
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