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Anti-Mouse ZNRF3 Polyclonal Antibody

Catalog #:   PMN08401 Specific References (13) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q5SSZ7
Overview

Catalog No.

PMN08401

Species reactivity

Mouse

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Mouse ZNRF3 (Lys53-Pro207).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

KIAA1133, RNF203, RING-type E3 ubiquitin transferase ZNRF3, ZNRF3, RING finger protein 203, Zinc/RING finger protein 3, E3 ubiquitin-protein ligase ZNRF3

Purification

Purified by antigen affinity column.

Accession

Q5SSZ7

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with ZNRF3 antibody (PMN08401) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 19 kDa
    Observed MW: 19 kDa
References

Structure-Guided Development of Chemically Tailored Peptide Binders of RNF43/ZNRF3 to Enable Versatile Design of Membrane Protein-Targeting PROTACs., PMID:40000409

Coactivation of Tie2 and Wnt signaling using an antibody-R-spondin fusion potentiates therapeutic angiogenesis and vessel stabilization in hindlimb ischemia., PMID:39607038

Get your receptors in a knot with new Wnt signaling agonists., PMID:38906109

Targeted protein degradation systems to enhance Wnt signaling., PMID:38847394

Potent and selective binders of the E3 ubiquitin ligase ZNRF3 stimulate Wnt signaling and intestinal organoid growth., PMID:38056465

Antibody targeting of E3 ubiquitin ligases for receptor degradation., PMID:36131013

Roadmap for Optimizing and Broadening Antibody-Based PROTACs for Degradation of Cell Surface Proteins., PMID:35481357

Longitudinal change of genetic variations in cetuximab-treated metastatic colorectal cancer., PMID:34315006

Unlike LGR4, LGR5 potentiates Wnt-β-catenin signaling without sequestering E3 ligases., PMID:33262293

Surrogate R-spondins for tissue-specific potentiation of Wnt Signaling., PMID:31914456

Anti-LRP5/6 VHHs promote differentiation of Wnt-hypersensitive intestinal stem cells., PMID:30664649

Whole exome sequencing to identify genetic markers for trastuzumab-induced cardiotoxicity., PMID:29247589

Molecular genetics and targeted therapy of WNT-related human diseases (Review)., PMID:28731148

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Anti-Mouse ZNRF3 Polyclonal Antibody [PMN08401]
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