Catalog No.
YMN41201
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
His192-Leu316
Predicted molecular weight
17.24 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8JZN1
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Macrophage galactose N-acetyl-galactosamine specific lectin 2, Macrophage galactose-type C-type lectin 2, Mgl2
LILRB4 specific overexpression in myeloid cells promotes tumor progression and immunosuppression in mouse models., PMID:40048761
Mgl2+ cDC2s coordinate fungal allergic airway type 2, but not type 17, inflammation in mice., PMID:39843887
Tetrandrine alleviates inflammation and promotes macrophage M2 polarization in gouty arthritis by NF-κB-mediated Lcp1., PMID:38430024
Fluoxetine rescues the depressive-like behaviour induced by reserpine and the altered emotional behaviour induced by nicotine withdrawal in zebrafish: Involvement of tyrosine hydroxylase., PMID:37593958
Elucidating the importance of the catabolic enzyme, methionine-gamma-lyase, in stresses during Arabidopsis seed development and germination., PMID:37346132
ARG1-expressing microglia show a distinct molecular signature and modulate postnatal development and function of the mouse brain., PMID:37169859
Cellular Proteomic Profiling Using Proximity Labeling by TurboID-NES in Microglial and Neuronal Cell Lines., PMID:37061046
Apigenin Inhibits the Progression of Osteoarthritis by Mediating Macrophage Polarization., PMID:37049677
Macrophage Gal/GalNAc lectin 2 (MGL2)+ peritoneal antigen presenting cells during Fasciola hepatica infection are essential for regulatory T cell induction., PMID:36271272
Lung Tumor Cells with Different Tn Antigen Expression Present Distinctive Immunomodulatory Properties., PMID:36233358
Serum Creatinine Levels and Nephrocheck® Values With and Without Correction for Urine Dilution-A Multicenter Observational Study., PMID:35252280
Effective CD4 T cell priming requires repertoire scanning by CD301b+ migratory cDC2 cells upon lymph node entry., PMID:34890253
Type 2 immunity plays an essential role for murine model of allergic contact dermatitis with mixed type 1/type 2 immune response., PMID:34763990
Study of C-reactive protein, procalcitonin, and immunocyte ratios in 194 patients with sepsis., PMID:34233608
The Tn antigen promotes lung tumor growth by fostering immunosuppression and angiogenesis via interaction with Macrophage Galactose-type lectin 2 (MGL2)., PMID:34144098
The FMRFamide Neuropeptide FLP-20 Acts as a Systemic Signal for Starvation Responses in Caenorhabditis elegans., PMID:34140426
Metabolic, Organoleptic and Transcriptomic Impact of Saccharomyces cerevisiae Genes Involved in the Biosynthesis of Linear and Substituted Esters., PMID:33919724
Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to GalNAc and the Tumor-Associated Tn Antigen., PMID:33724805
CD301 mediates fusion in IL-4-driven multinucleated giant cell formation., PMID:33571108
Absence of metabotropic glutamate receptor homolog(s) accelerates acetylcholine neurotransmission in Caenorhabditis elegans., PMID:33493646
Knockdown of milk-fat globule EGF factor-8 suppresses glioma progression in GL261 glioma cells by repressing microglial M2 polarization., PMID:32324268
Enhanced Immune Response Against the Thomsen-Friedenreich Tumor Antigen Using a Bivalent Entirely Carbohydrate Conjugate., PMID:32183149
Transcriptome profiling of tolerogenic dendritic cells conditioned with dual mTOR kinase inhibitor, AZD8055., PMID:32058927
Macrophage galactose lectin is critical for Kupffer cells to clear aged platelets., PMID:31978220
MGL1 Receptor Plays a Key Role in the Control of T. cruzi Infection by Increasing Macrophage Activation through Modulation of ERK1/2, c-Jun, NF-κB and NLRP3 Pathways., PMID:31906385
dPGS Regulates the Phenotype of Macrophages via Metabolic Switching., PMID:31631571
Macrophage galactose-type lectin (MGL) is induced on M2 microglia and participates in the resolution phase of autoimmune neuroinflammation., PMID:31248427
Glutamate spillover in C. elegans triggers repetitive behavior through presynaptic activation of MGL-2/mGluR5., PMID:31015396
Unleashing Type-2 Dendritic Cells to Drive Protective Antitumor CD4+ T Cell Immunity., PMID:30955881
High prevalence of division II (cfiA positive) isolates among blood stream Bacteroides fragilis in Slovenia as determined by MALDI-TOF MS., PMID:30716401
Mgl2 Is a Hypothetical Methyltransferase Involved in Exopolysaccharide Production, Biofilm Formation, and Motility in Rhizobium leguminosarum bv. trifolii., PMID:30681888
Myofibroblast proliferation and heterogeneity are supported by macrophages during skin repair., PMID:30467144
Yeast two-hybrid screening identifies MPZ-1 and PTP-1 as candidate scaffolding proteins of metabotropic glutamate receptors in Caenorhabditis elegans., PMID:30417267
Perivascular dendritic cells elicit anaphylaxis by relaying allergens to mast cells via microvesicles., PMID:30409859
Modulating Macrophage Polarization through CCR2 Inhibition and Multivalent Engagement., PMID:29791797
Imatinib prevents lung cancer metastasis by inhibiting M2-like polarization of macrophages., PMID:29730267
Celastrol inhibits cancer metastasis by suppressing M2-like polarization of macrophages., PMID:29614269
CD301b/MGL2+ Mononuclear Phagocytes Orchestrate Autoimmune Cardiac Valve Inflammation and Fibrosis., PMID:29386201
Effect of Porphyromonas gingivalis infection in the placenta and umbilical cord in pregnant mice with low birth weight., PMID:29334319
Skin-Specific CD301b+ Dermal Dendritic Cells Drive IL-17-Mediated Psoriasis-Like Immune Response in Mice., PMID:29138056
Immunological evaluation of some antigens of Lucilia sericata larvae., PMID:29114146
Human amyloid β peptide and tau co-expression impairs behavior and causes specific gene expression changes in Caenorhabditis elegans., PMID:28982592
GalNAc-Tyrosine Is a Ligand of Plant Lectins, Antibodies, and Human and Murine Macrophage Galactose-Type Lectins., PMID:28644609
BCL6 mediates the effects of Gastrodin on promoting M2-like macrophage polarization and protecting against oxidative stress-induced apoptosis and cell death in macrophages., PMID:28315684
IL-27 Facilitates Skin Wound Healing through Induction of Epidermal Proliferation and Host Defense., PMID:28132857
CD301b+ dendritic cells stimulate tissue-resident memory CD8+ T cells to protect against genital HSV-2., PMID:27827367
CD301b(+) Mononuclear Phagocytes Maintain Positive Energy Balance through Secretion of Resistin-like Molecule Alpha., PMID:27566941
CD301b+ Macrophages Are Essential for Effective Skin Wound Healing., PMID:27287183
MGL2/YMR210w encodes a monoacylglycerol lipase in Saccharomyces cerevisiae., PMID:26991558
Fatty acid oxidation in macrophage polarization., PMID:26882249
For research use only. Not for human or drug use.
