Catalog No.
YMF42801
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Phe26-Gly130
Predicted molecular weight
39.79 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P61364
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
OSTN, Osteocrin, Musclin
Single-cell RNA sequencing of adult primate neocortex reveals the regulatory dynamics of neural plasticity., PMID:40385068
Exploring the functional variations of key candidate genes affecting egg production by hypothalamic-pituitary-ovarian axis in chickens., PMID:40132314
16S rRNA and transcriptome analysis revealed the regulatory mechanism of Romboutsia lituseburensis on serum immunoglobulin levels in geese., PMID:40086254
Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and implicates causal proteins for Alzheimer's disease., PMID:39528825
Genome-wide variation study and inter-tissue communication analysis unveil regulatory mechanisms of egg-laying performance in chickens., PMID:39152103
Haemodynamic, hormonal and renal actions of osteocrin in normal sheep., PMID:38890799
Exercise-induced Musclin determines the fate of fibro-adipogenic progenitors to control muscle homeostasis., PMID:38232727
Capra hircus outliers markers in Brazil: Searching for genomic regions under the action of natural selection., PMID:37882366
Decreased serum musclin concentration is independently associated with the high prevalence of sarcopenia in Chinese middle-elderly patients with type 2 diabetes mellitus., PMID:37737466
Genome-Wide Meta-Analysis of Cerebrospinal Fluid Biomarkers in Alzheimer's Disease and Parkinson's Disease Cohorts., PMID:37539664
The muscle-enriched myokine Musclin impairs beige fat thermogenesis and systemic energy homeostasis via Tfr1/PKA signaling in male mice., PMID:37468484
Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and informs causal proteins for Alzheimer's disease., PMID:37333337
The natriuretic peptide receptor agonist osteocrin disperses Pseudomonas aeruginosa biofilm., PMID:37252226
Mustn1 ablation in skeletal muscle results in increased glucose tolerance concomitant with upregulated GLUT expression in male mice., PMID:37170065
The correlation of serum musclin with diabetic nephropathy., PMID:37137178
Myokine Musclin Is Critical for Exercise-Induced Cardiac Conditioning., PMID:37047496
Comparison of perioperative serum osteocrin concentrations between surgical techniques in dogs with cranial cruciate ligament rupture., PMID:36917865
Identification of visual cortex cell types and species differences using single-cell RNA sequencing., PMID:36371428
Nestin and osteocrin mRNA increases in human semitendinosus myotendinous junction 7 days after a single bout of eccentric exercise., PMID:35428952
Osteocrin alleviates cardiac hypertrophy via attenuating oxidative stress., PMID:35218795
Identification of Synovial Fibroblast-Associated Neuropeptide Genes and m6A Factors in Rheumatoid Arthritis Using Single-Cell Analysis and Machine Learning., PMID:35186167
Skeletal muscle derived Musclin protects the heart during pathological overload., PMID:35013221
Osteocrin ameliorates adriamycin nephropathy via p38 mitogen-activated protein kinase inhibition., PMID:34750411
Control of osteocyte dendrite formation by Sp7 and its target gene osteocrin., PMID:34725346
Efficacy of high-intensity interval- or continuous aerobic-training on insulin resistance and muscle function in adults with metabolic syndrome: a clinical trial., PMID:34687360
Musclin Is Related to Insulin Resistance and Body Composition, but Not to Body Mass Index or Cardiorespiratory Capacity in Adults., PMID:34674511
Osteocrin, a bone-derived humoral factor, exerts a renoprotective role in ischemia-reperfusion injury in mice., PMID:34610136
Mechanical load regulates bone growth via periosteal Osteocrin., PMID:34260913
RNA sequencing and immunofluorescence of the myotendinous junction of mature horses and humans., PMID:34260300
Myokine Responses to Exercise in a Rat Model of Low/High Adaptive Potential., PMID:34177798
Osteocrin, a novel myokine, prevents diabetic cardiomyopathy via restoring proteasomal activity., PMID:34135313
Decreased muscle-derived musclin by chronic resistance exercise is associated with improved insulin resistance in rats with type 2 diabetes., PMID:33955191
Evidence Supporting the Regulatory Relationships through a Paracrine Pathway between the Sternum and Pectoral Muscles in Ducks., PMID:33804959
Natriuretic peptide receptor-C releases and activates guanine nucleotide-exchange factor H1 in a ligand-dependent manner., PMID:33740666
Muscular G9a Regulates Muscle-Liver-Fat Axis by Musclin Under Overnutrition in Female Mice., PMID:32994276
Osteocrin attenuates inflammation, oxidative stress, apoptosis, and cardiac dysfunction in doxorubicin-induced cardiotoxicity., PMID:32618439
Serum Level of Musclin Is Elevated Following Severe Burn., PMID:31187123
The Role of Myokines and Adipokines in Hypertension and Hypertension-related Complications., PMID:31133682
C/EBPβ mediates palmitate-induced musclin expression via the regulation of PERK/ATF4 pathways in myotubes., PMID:30964708
Glucosamine induces increased musclin gene expression through endoplasmic reticulum stress-induced unfolding protein response signaling pathways in mouse skeletal muscle cells., PMID:30602124
Involvement of natriuretic peptide system in C2C12 myocytes., PMID:30519782
Sex-specific genetic predictors of Alzheimer's disease biomarkers., PMID:29967939
The Effects of PPAR Stimulation on Cardiac Metabolic Pathways in Barth Syndrome Mice., PMID:29695963
Efficacy of high-intensity, low-volume interval training compared to continuous aerobic training on insulin resistance, skeletal muscle structure and function in adults with metabolic syndrome: study protocol for a randomized controlled clinical trial (Intraining-MET)., PMID:29482601
A New Secretory Peptide of Natriuretic Peptide Family, Osteocrin, Suppresses the Progression of Congestive Heart Failure After Myocardial Infarction., PMID:29326144
Circulating osteocrin stimulates bone growth by limiting C-type natriuretic peptide clearance., PMID:28990933
A potent and selective natriuretic peptide receptor-3 blocker 11-mer peptide created by hybridization of musclin and atrial natriuretic peptide., PMID:28596054
Increased circulating levels of musclin in newly diagnosed type 2 diabetic patients., PMID:28185530
Osteocrin, a peptide secreted from the heart and other tissues, contributes to cranial osteogenesis and chondrogenesis in zebrafish., PMID:27993976
Primate Neurons Flex Their Musclin., PMID:27883900
For research use only. Not for human or drug use.
