Catalog No.
YMD72401
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Gly491-Glu716
Predicted molecular weight
27.12 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P26928
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Macrophage-stimulating protein, D3F15S2, MSP, DNF15S2, MST1, HGFL, Macrophage stimulatory protein, Hepatocyte growth factor-like protein
Crosstalk between MST1-Hippo and Wnt/β-Catenin, Notch, and PI3K/Akt pathways in cardiac physiology and pathology., PMID:40489018
Vitamin D promotes wound healing in aged skin by modulating inflammation, angiogenesis, and EMT via the Hippo pathway., PMID:40466431
LncRNA AK020546 Alleviates Myocardial Ischemia-Reperfusion Injury via Suppressing METTL14/m6A/MST1 Axis-Mediated Ferroptosis., PMID:40465027
Systematic Mendelian randomization of the human plasma proteome to identify therapeutic targets linking aging and frailty to perioperative delirium., PMID:40451486
MST1 modulates inflammatory responses by targeting the NF-κB/NLRP3 pathway in LPS-induced acute lung injury., PMID:40434446
E-cadherin inhibits the proliferation and migration of human colorectal cancer cells through Hippo signaling pathway., PMID:40421484
Macrophage Notch1 drives septic cardiac dysfunction by impairing mitophagy and promoting NLRP3 activation., PMID:40414862
Therapeutic determinants of melatonin in hepatitis caused by coxsackievirus B3 infection., PMID:40393543
Knockdown of BAP31 Suppresses Tumorigenesis and Stemness in Breast Cancer Cells via the Hippo Pathway., PMID:40332113
Harnessing the FGFR2/NF2/YAP signaling-dependent necroptosis to develop an FGFR2/IL-8 dual blockade therapeutic strategy., PMID:40319089
[Zheng Gan Decoction inhibits diethylnitrosamine-induced hepatocellular carcinoma in rats by activating the Hippo/YAP signaling pathway]., PMID:40294930
The Hippo pathway in bone and cartilage: implications for development and disease., PMID:40292098
Rinsenoside Rg1 and its involvement in Hippo-YAP signaling pathway alleviating symptoms of depressive-like behavior., PMID:40281108
Mammalian Ste20-like kinase 1 regulates AMPK to mitigate the progression of non-alcoholic fatty liver disease., PMID:40247356
Non-canonical HIPPO-MST1/2 promotes hyper-proliferation of pulmonary vascular cells through CDC20., PMID:40236147
Circular RNA circSTX12 regulates osteo-adipogenic balance and proliferation of BMSCs in senile osteoporosis., PMID:40192802
Protective effect of melatonin against blue light-induced cell damage via the TRPV1-YAP pathway in cultured human epidermal keratinocytes., PMID:40183558
Ferulic acid lipid nano capsules versus its native form in alleviating diabetic nephropathy induced in rats through TGF-β1/Hippo pathway crosstalk modulation., PMID:40164664
Enhancement of functional insulin-producing cell differentiation from embryonic stem cells through MST1-silencing., PMID:40108649
Hippo pathway activation mediates cardiomyocyte ferroptosis to promote dilated cardiomyopathy through downregulating NFS1., PMID:40107016
Alterations in the Hippo Signaling Pathway During Adenogenesis Impairment in Postnatal Mouse Uterus., PMID:40106220
Mechanism of Lung Fibrosis Caused by Rare Earth Samarium Oxide Through Hippo Signaling Pathway and the Intervention of GBE., PMID:40102356
Pharmacological regulators of Hippo pathway: Advances and challenges of drug development., PMID:40100056
Phenylpropanoids of Eleutherococcus senticosus (Rupr. & maxim.) maxim. Alleviate oxidative stress in Alzheimer's disease in vitro and in vivo models by regulating Mst1 and affecting the Nrf2/Sirt3 pathway., PMID:40081261
Phosphorylation of an RNA-Binding Protein Rck/Me31b by Hippo Is Essential for Adipose Tissue Aging., PMID:40070010
Mst1 knockout and Nrf2 activation alleviate diabetic cardiomyopathy pathogenesis through autophagy modulation in type 2 diabetic mice., PMID:40054589
MISP Suppresses Ferroptosis via MST1/2 Kinases to Facilitate YAP Activation in Non-Small Cell Lung Cancer., PMID:40019375
Kibra knockdown inhibits the aberrant Hippo pathway, suppresses renal cyst formation and ameliorates renal fibrosis in nphp1KO mice., PMID:39995111
CircAKT3 promotes prostate cancer proliferation and metastasis by enhancing the binding of RPS27A and RPL11., PMID:39994725
A negative feedback loop between small GTPase Rap1 and mammalian tumor suppressor homologue KrsB regulates cell-substrate adhesion in Dictyostelium., PMID:39937679
YAP/TAZ-associated cell signaling - at the crossroads of cancer and neurodevelopmental disorders., PMID:39936032
Decoding gene expression profiles of Hippo signaling pathway components in breast cancer., PMID:39928181
Inhibition of MST1/2 Kinases of the Hippo Signaling Pathway Enhances Antitumor Chemotherapy in Hematological Cancers., PMID:39907893
The autophagy component LC3 regulates lymphocyte adhesion via LFA1 transport in response to outside-in signaling., PMID:39905041
Lead exposure promotes NF2-wildtype meningioma cell proliferation through the Merlin-Hippo signaling pathway., PMID:39894505
Dual inhibition of Mst1 and Mst2 exacerbates cardiac dysfunction during pressure overload stress in mice., PMID:39892959
Activation of the conserved Hippo kinases by inflammasome-triggered proteolytic cleavage controls programmed cell death in macrophages., PMID:39883842
miR-301a-mediated crosstalk between the Hedgehog and HIPPO/YAP signaling pathways promotes pancreatic cancer., PMID:39846248
[Effect of Huayu Tongluo moxibustion on learning-memory ability in rats with vascular dementia based on hippocampal Mst1/NF-κB p65 pathway]., PMID:39777880
Increased Expression of MST1 in Patients With Epilepsy and in a Rat Model of Epilepsy., PMID:39729046
Macrophage MST1 protects against schistosomiasis-induced liver fibrosis by promoting the PPARγ-CD36 pathway and suppressing NF-κB signaling., PMID:39700261
Overexpression of PDSS2-Del2 in HCC promotes tumor metastasis by interacting with macrophages., PMID:39695147
USP20 mediates malignant phenotypic changes in bladder cancer through direct interactions with YAP1., PMID:39674114
MST1 interactomes profiling across cell death in esophageal squamous cell carcinoma., PMID:39664081
Activation of MST1 protects filtration barrier integrity of diabetic kidney disease in mice through restoring the tight junctions of glomerular endothelial cells., PMID:39643641
Epstein-Barr virus infection upregulates extracellular OLFM4 to activate YAP signaling during gastric cancer progression., PMID:39627192
Centromere protein K enhances the activation of YAP1/TAZ signal cascade to drive the progression of clear cell renal cell carcinoma., PMID:39617260
The Hippo Signaling Pathway, Reactive Oxygen Species Production, and Oxidative Stress: A Two-Way Traffic Regulation., PMID:39594616
MST1, a novel therapeutic target for Alzheimer's disease, regulates mitochondrial homeostasis by mediating mitochondrial DNA transcription and the PI3K-Akt-ROS pathway., PMID:39578795
A focus on c-Jun-N-terminal kinase signaling in sepsis-associated multiple organ dysfunction: Mechanisms and therapeutic strategies., PMID:39536486
For research use only. Not for human or drug use.
