Catalog No.
YMD47901
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Arg409-Asp702
Predicted molecular weight
35.98 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
B7ZWP2
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
K-sam, KSAM, CD332, Keratinocyte growth factor receptor, Fibroblast growth factor receptor 2, FGFR-2, FGFR2, KGFR, BEK
Comprehensive morphological, immunohistochemical, and molecular characterization of congenital pulmonary airway malformation (CPAM)., PMID:40473982
Suppression of NRAS-mutant melanoma growth with NRAS-targeting Antisense Oligonucleotide treatment reveals therapeutically relevant kinase co-dependencies., PMID:40473796
The Role of FGFR2 on Proliferation, Apoptosis and Glucose Metabolism of Breast Cancer Cells., PMID:40460389
Fibroblast growth factor 2 stimulates differentiation of mechanically-stressed human periodontal ligament fibroblasts into cementoblasts., PMID:40434329
Fibroblast growth factor 7 (FGF7) and its receptor FGFR2IIIb during the peri-implantation period of dromedary camels: A comparative analysis between left and right uterine horns., PMID:40424945
Highly elevated sepsis biomarkers in advanced cholangiocarcinoma without sepsis: A case report and literature review., PMID:40419900
Fibroblast growth factor receptor expression in hemangioblastomas: A novel therapeutic target., PMID:40393028
Discovery of LC-SF-14, a selective dual inhibitor of SHP2 and FGFR for the treatment of FGFR2-driven gastric cancer., PMID:40381223
Rational Method for Structural Simplification as Key Step in Hit Discovery: The Case of FGFR2 and IGF1R Dual Inhibitors., PMID:40362694
Further Evidence of Early-Onset Osteoporosis and Bone Fractures as a New FGFR2-Related Phenotype., PMID:40362441
Generation of a biliary tract cancer cell line atlas identifies molecular subtypes and therapeutic targets., PMID:40353839
Genetic re-classification of combined hepatocellular-cholangiocarcinoma and small duct type intrahepatic cholangiocarcinoma., PMID:40349569
Fibroblast growth factor 7 facilitates invasion of human trophoblast cells through the JNK pathway during pregnancy., PMID:40344910
Efficacy of 2 different fibroblast growth factor receptor-inhibitors in a patient with extrahepatic cholangiocarcinoma harboring an FGFR2 mutation: a case report., PMID:40338217
Harnessing the FGFR2/NF2/YAP signaling-dependent necroptosis to develop an FGFR2/IL-8 dual blockade therapeutic strategy., PMID:40319089
Clinicopathological and molecular characterization of KRAS wild-type pancreatic ductal adenocarcinomas reveals precursor lesions with oncogenic mutations and fusions in RAS pathway genes., PMID:40317966
The Role of Fibroblast Growth Factor Receptor 2 as A Prognostic Biomarker in Colorectal Adenocarcinoma., PMID:40302086
Residue-Selective Inhibitors Discovery via Covalent DNA-Encoded Chemical Libraries with Diverse Warheads., PMID:40292872
FGFR2 residence in primary cilia is necessary for epithelial cell signaling., PMID:40257378
Treating intrahepatic cholangiocarcinoma with pemigatinib: two case reports of Nordic patients., PMID:40230323
FOS-driven inflammatory CAFs promote colorectal cancer liver metastasis via the SFRP1-FGFR2-HIF1 axis., PMID:40225580
Claudin 18.2: a promising actionable target in biliary tract cancers., PMID:40215597
Genetic predictors of unexpected recurrence in low-risk endometrial cancer: A comprehensive genomic analysis reveals FGFR2 as a risk factor and a rare fatal POLE-mutated recurrence., PMID:40209441
Fibroblast growth factor receptor 2 (FGFR2) genetic polymorphisms contribute to fused roots in human molars., PMID:40208883
FGFR as a Predictive Marker for Targeted Therapy in Gastrointestinal Malignancies: A Systematic Review., PMID:40205008
Colonic epithelial-derived FGF1 drives intestinal stem cell commitment toward goblet cells to suppress inflammatory bowel disease., PMID:40188210
FGFR2 Abrogation Intercepts Pancreatic Ductal Adenocarcinoma Development., PMID:40170241
CAUSAL ASSOCIATION BETWEEN SEPSIS AND FIBROBLAST GROWTH FACTORS AS WELL AS THEIR RECEPTORS LEVELS: A TWO-SAMPLE MENDELIAN RANDOMIZATION STUDY., PMID:40138723
Selective degradation of FGFR1/2 overcomes antiestrogen resistance in ER+ breast cancer with FGFR1/2 alterations., PMID:40127812
Targeting COPA to Enhance Erdafitinib Sensitivity in FGFR-Altered Bladder Cancer., PMID:40112217
Bioinformatics analysis explores key pathways and hub genes in central precocious puberty., PMID:40110745
The Prognostic Significance and Co-Expression of Fibroblast Growth Factor Receptor 2 and c-Met in Endometrial Cancer., PMID:40109959
RNA-binding protein SAMD4A targets FGF2 to regulate cardiomyocyte lineage specification from human embryonic stem cells., PMID:40102919
Comment on "Intrahepatic cholangiocarcinoma with FGFR alterations: A series of Chinese cases with an emphasis on their clinicopathologic and genetic features"., PMID:40090821
Esrp1 and Esrp2 regulate the stability of tmc1/2a mRNAs in zebrafish sensory hair cells., PMID:40086870
Development and Characterization of Three Novel FGFR Inhibitor Resistant Cervical Cancer Cell Lines to Help Drive Cervical Cancer Research., PMID:40076427
Differences in Formation of Prepuce and Urethral Groove During Penile Development Between Guinea Pigs and Mice Are Controlled by Differential Expression of Shh, Fgf10 and Fgfr2., PMID:40072077
Single-cell analysis reveals transcriptomic features and therapeutic targets in primary pulmonary lymphoepithelioma-like carcinoma., PMID:40057671
Effect of phoenixin-14 on angiogenesis, cell proliferation, and apoptosis in porcine corpus luteum: Role of GPR173 and ERK1/2, AKT, and AMPK signal pathway., PMID:40037032
Tasurgratinib Succinate: First Approval., PMID:40035947
Identification of potent biparatopic antibodies targeting FGFR2 fusion-driven cholangiocarcinoma., PMID:40014401
Arctiin attenuated NASH by inhibiting glycolysis and inflammation via FGFR2/CSF1R signaling., PMID:40010483
Postnatal Progressive Craniosynostosis: An Unusual Case Presentation Leading to Cascade Diagnosis for Multiple Generations., PMID:40001279
Caveolin 1 and 2 enhance the proliferative capacity of BCAM-positive corneal progenitors., PMID:39994275
Clinical Use of Liquid-Based Comprehensive Genomic Profiling in Gastrointestinal Stromal Tumors., PMID:39984125
Extrachromosomal DNA Dynamics Contribute to Intratumoral Receptor Tyrosine Kinase Genetic Heterogeneity and Drug Resistance in Gastric Cancer., PMID:39969515
Deep immune profiling of intrahepatic cholangiocarcinoma with CODEX multiplexed imaging., PMID:39969434
FGFR2/3 Gene Alterations and Clinical Outcomes in Advanced/Metastatic Urothelial Cancer in Japan: MONSTAR-SCREEN Database Study., PMID:39933925
Phase 2 study of futibatinib in patients with gastric or gastroesophageal junction cancer harboring FGFR2 amplifications., PMID:39919334
For research use only. Not for human or drug use.
