Catalog No.
YMC10701
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Ser25-Ser108
Predicted molecular weight
37.45 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
A2RTV8
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
RLN1, Prorelaxin H1
Role of Relaxin Signaling in Cancer: A Review., PMID:39547477
Relaxin-2 is a novel biomarker for differentiated thyroid carcinoma in humans., PMID:38815632
Identification and Quantification of Human Relaxin Proteins by Immunoaffinity-Mass Spectrometry., PMID:38739617
Differentially Expressed Genes Regulating Glutathione Metabolism, Protein-Folding, and Unfolded Protein Response in Pancreatic β-Cells in Type 2 Diabetes Mellitus., PMID:37569434
Regulation of appetite-related neuropeptides by Panax ginseng: A novel approach for obesity treatment., PMID:35818423
Changes in Neuropeptide Prohormone Genes among Cetartiodactyla Livestock and Wild Species Associated with Evolution and Domestication., PMID:35622775
A bibliometric review of peripartum cardiomyopathy compared to other cardiomyopathies using artificial intelligence and machine learning., PMID:35340600
Relaxin inhibits renal fibrosis and the epithelial-to-mesenchymal transition via the Wnt/β-catenin signaling pathway., PMID:35311469
Detailed quantum mechanical studies on bioactive benzodiazepine derivatives and their adsorption over graphene sheets., PMID:32272424
Ocular Phenotype of Relaxin Gene Knockout (Rln-/-) Mice., PMID:32141786
Relaxin reverses maladaptive remodeling of the aged heart through Wnt-signaling., PMID:31811156
Sensitivity of the fasciae to sex hormone levels: Modulation of collagen-I, collagen-III and fibrillin production., PMID:31557257
Relaxin gene delivery mitigates liver metastasis and synergizes with check point therapy., PMID:31278269
Targeted genetic screening in mice through haploid embryonic stem cells identifies critical genes in bone development., PMID:31265461
Emerging roles for the relaxin/RXFP1 system in cancer therapy., PMID:30763603
Transcriptional up-regulation of relaxin-3 by Nur77 attenuates β-adrenergic agonist-induced apoptosis in cardiomyocytes., PMID:30006349
Abnormal extracellular matrix remodelling in the cervix of pregnant relaxin-deficient mice is not associated with reduced matrix metalloproteinase expression or activity., PMID:29533760
Alterations of relaxin and its receptor system components in experimental diabetic cardiomyopathy rats., PMID:28776188
Site-related Effects of Relaxin in the Gastrointestinal Tract Through Nitric Oxide Signalling: An Updated Report., PMID:28606038
Serelaxin treatment promotes adaptive hypertrophy but does not prevent heart failure in experimental peripartum cardiomyopathy., PMID:28453725
Evidence of altered brain regulatory gene expression in tobacco-exposed fetuses., PMID:28130959
Relaxin serum levels in acute heart failure are associated with pulmonary hypertension and right heart overload., PMID:27488261
A preliminary investigation of the effect of relaxin on bone remodelling in suture expansion., PMID:27141932
Identification of a novel fusion transcript between human relaxin-1 (RLN1) and human relaxin-2 (RLN2) in prostate cancer., PMID:26499396
Relaxin-related gene expression differs between anadromous and stream-resident stickleback (Gasterosteus aculeatus) following seawater transfer., PMID:24973563
C1q-tumour necrosis factor-related protein 8 (CTRP8) is a novel interaction partner of relaxin receptor RXFP1 in human brain cancer cells., PMID:24014093
Acute treatment with relaxin attenuates the injury/dysfunction induced by renal ischemia/reperfusion injury., PMID:24640578
Mechanisms for relaxin's modulation of MMPs and matrix loss in fibrocartilages., PMID:24640575
Relaxin and preterm birth., PMID:24640563
Relaxin and the control of primate parturition., PMID:24640561
Relaxin, insulin and diabetes: an intriguing connection., PMID:22698078
Up-regulating relaxin expression by G-quadruplex interactive ligand to achieve antifibrotic action., PMID:22673230
Characterization, cDNA cloning and expression pattern of relaxin gene during embryogenesis of Danio rerio., PMID:22671140
Gene turnover and differential retention in the relaxin/insulin-like gene family in primates., PMID:22405815
Heterozygous deletion at the RLN1 locus in a family with testicular germ cell cancer identified by integrating copy number variation data with phenome and interactome information., PMID:21696394
RegNetB: predicting relevant regulator-gene relationships in localized prostate tumor samples., PMID:21682879
Relaxin is up-regulated in the rat ovary by orthodontic tooth movement., PMID:21410550
Polymorphisms in the promoter region of relaxin-2 and preterm birth: involvement of relaxin in the etiology of preterm birth., PMID:20023247
Estrogen and TCDD influence RLN2 gene activity in estrogen receptor-positive human breast cancer cells., PMID:19416221
Association studies of lung function in mice., PMID:18672739
High-resolution copy number and gene expression microarray analyses of head and neck squamous cell carcinoma cell lines of tongue and larynx., PMID:18314910
The effects of relaxin on extracellular matrix remodeling in health and fibrotic disease., PMID:18161483
Endogenous relaxin does not affect chronic pressure overload-induced cardiac hypertrophy and fibrosis., PMID:17991721
Candidate genes controlling pulmonary function in mice: transcript profiling and predicted protein structure., PMID:17804602
Reversal by relaxin of altered ileal spontaneous contractions in dystrophic (mdx) mice through a nitric oxide-mediated mechanism., PMID:17522128
Relaxin promotes prostate cancer progression., PMID:17363522
Endogenous relaxin is a naturally occurring modulator of experimental renal tubulointerstitial fibrosis., PMID:17095590
The effects of relaxin and estrogen deficiency on collagen deposition and hypertrophy of nonreproductive organs., PMID:16935837
'Relaxin' the stiffened heart and arteries: the therapeutic potential for relaxin in the treatment of cardiovascular disease., PMID:16814863
Functional expression of mouse relaxin and mouse relaxin-3 in the lung from an Ebola virus glycoprotein-pseudotyped lentivirus via tracheal delivery., PMID:16709614
For research use only. Not for human or drug use.
