Catalog No.
YHN35401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn621-Gly735
Predicted molecular weight
16.27 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9ULG6
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Cell cycle progression restoration protein 8, CCPG1, CPR8, CCP8, KIAA1254, Cell cycle progression protein 1
RETREG1-mediated reticulophagy is activated by an ATF4-CEBPG/C/EBPγ heterodimer and confers protection against lipotoxicity., PMID:40437698
ATP2A2 regulates STING1/MITA-driven signal transduction including selective autophagy., PMID:40265346
Reticulophagy and viral infection., PMID:39394962
Targeted proteomics addresses selectivity and complexity of protein degradation by autophagy., PMID:39245437
Structural basis for TNIP1 binding to FIP200 during mitophagy., PMID:39059492
Drp1 Aggravates Copper Nanoparticle-Induced ER-Phagy by Disturbing Mitochondria-Associated Membranes in Chicken Hepatocytes., PMID:38986054
USP20 deubiquitinates and stabilizes the reticulophagy receptor RETREG1/FAM134B to drive reticulophagy., PMID:38705724
Endoplasmic Reticulum Selective Autophagy Alleviates Anthracycline-Induced Cardiotoxicity., PMID:37969644
Clinical and prognostic significance of CCPG1 in hepatocellular carcinoma., PMID:37702448
Specific Learning Disorders: Variation Analysis of 15 Candidate Genes in 9 Multiplex Families., PMID:37629793
SARS-CoV-2 nonstructural protein 6 triggers endoplasmic reticulum stress-induced autophagy to degrade STING1., PMID:37482689
FOXO3 Deficiency in Neutrophils Drives Colonic Inflammation and Tumorigenesis., PMID:37298680
Cargo-interacting regions (CIR) of CCPG1 capture ER luminal cargos for reticulophagy., PMID:40395301
Signal-Retaining Autophagy Indicator as a Quantitative Imaging Method for ER-Phagy., PMID:37190043
Sodium arsenite-induced cytotoxicity is regulated by BNIP3L/Nix-mediated endoplasmic reticulum stress responses and CCPG1-mediated endoplasmic reticulum-phagy., PMID:36925093
The Activation of Reticulophagy by ER Stress through the ATF4-MAP1LC3A-CCPG1 Pathway in Ovarian Granulosa Cells Is Linked to Apoptosis and Necroptosis., PMID:36769070
Whole-Exome Sequencing Indicated New Candidate Genes Associated with Unilateral Cryptorchidism in Pigs., PMID:36758533
CCPG1 recognizes endoplasmic reticulum luminal proteins for selective ER-phagy., PMID:36735498
Melatonin restores endoplasmic reticulum homeostasis to protect injured neurons in a rat model of chronic cervical cord compression., PMID:36732085
Chenodeoxycholic Acid (CDCA) Promoted Intestinal Epithelial Cell Proliferation by Regulating Cell Cycle Progression and Mitochondrial Biogenesis in IPEC-J2 Cells., PMID:36421471
CCPG1 involved in corneal Aspergillus fumigatus infection., PMID:35450172
Therapeutic regulation of autophagy in hepatic metabolism., PMID:35127371
GNA14 stimulation of KLF7 promotes malignant growth of endometrial cancer through upregulation of HAS2., PMID:33892667
Phosphorylation regulates the binding of autophagy receptors to FIP200 Claw domain for selective autophagy initiation., PMID:33692357
A novel reticulophagy receptor, Epr1: a bridge between the phagophore protein Atg8 and ER transmembrane VAP proteins., PMID:33121335
ATF4 links ER stress with reticulophagy in glioblastoma cells., PMID:33111629
Puncta intended: connecting the dots between autophagy and cell stress networks., PMID:32507070
Organelle-specific autophagy in inflammatory diseases: a potential therapeutic target underlying the quality control of multiple organelles., PMID:32048886
TEX264 is a major receptor for mammalian reticulophagy., PMID:31362563
An N-terminal-truncated isoform of FAM134B (FAM134B-2) regulates starvation-induced hepatic selective ER-phagy., PMID:31101736
Emerging Principles of Selective ER Autophagy., PMID:31100386
Intrinsically Disordered Protein TEX264 Mediates ER-phagy., PMID:31006538
ATL3 Is a Tubular ER-Phagy Receptor for GABARAP-Mediated Selective Autophagy., PMID:30773365
Molecular insights in the pathogenesis of classical Ehlers-Danlos syndrome from transcriptome-wide expression profiling of patients' skin fibroblasts., PMID:30716086
ER-phagy at a glance., PMID:30177506
CCPG1, a cargo receptor required for reticulophagy and endoplasmic reticulum proteostasis., PMID:29916296
CCPG1 is a noncanonical autophagy cargo receptor essential for reticulophagy and pancreatic ER proteostasis., PMID:29911925
Endoplasmic reticulum turnover: ER-phagy and other flavors in selective and non-selective ER clearance., PMID:29744037
A Dual Binding Receptor for ER-phagy., PMID:29401415
CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis., PMID:29290589
miR-498 promotes cell proliferation and inhibits cell apoptosis in retinoblastoma by directly targeting CCPG1., PMID:29247256
ER homeostasis and autophagy., PMID:29233873
Curcumin alters gene expression-associated DNA damage, cell cycle, cell survival and cell migration and invasion in NCI-H460 human lung cancer cells in vitro., PMID:26238775
Ccpg1, a novel scaffold protein that regulates the activity of the Rho guanine nucleotide exchange factor Dbs., PMID:17000758
For research use only. Not for human or drug use.
