Catalog No.
YHN34901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly547-Met816
Predicted molecular weight
33.07 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9UBF8
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Phosphatidylinositol 4-kinase beta, PIK4CB, PI4Kbeta, PI4K92, PI4KB, PI4K-beta, PI4KIII, PtdIns 4-kinase beta, NPIK
Dichotomous roles of ACBD3 in NSCLC growth and metastasis., PMID:40189704
Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4KB axis., PMID:40055523
Targeting PI4KB and Src/Abl host kinases as broad-spectrum antiviral strategy: Myth or real opportunity?, PMID:39922541
Apolipoprotein-L Functions in Membrane Remodeling., PMID:39768205
ARMH3 is an ARL5 effector that promotes PI4KB-catalyzed PI4P synthesis at the trans-Golgi network., PMID:39580461
Apolipoprotein-L1 (APOL1): From Sleeping Sickness to Kidney Disease., PMID:39451256
PI4KB is an essential host factor for duck hepatitis a virus 1 replication and translation., PMID:39393728
Macrophages regulate plaque progression in diabetic Apoe-/- mice dependent on Pi4p/Nlrp3 signaling pathway., PMID:39222595
DGARM/C10orf76/ARMH3 for Ceramide Transfer Zone at the Endoplasmic Reticulum-Distal Golgi Contacts., PMID:38515862
The Janus-faced functions of Apolipoproteins L in membrane dynamics., PMID:38478101
The activation of the adaptor protein STING depends on its interactions with the phospholipid PI4P., PMID:38470955
Locational and functional characterization of PI4KB in the mouse embryo., PMID:38230579
N-terminal acetyltransferase 6 facilitates enterovirus 71 replication by regulating PI4KB expression and replication organelle biogenesis., PMID:38189249
Inhibition of Pi4kb activity causes malformation of vestibular apparatus in zebrafish by downregulating hey1., PMID:38135256
Apolipoproteins L1 and L3 control mitochondrial membrane dynamics., PMID:38041817
Systematic identification of gene combinations to target in innate immune cells to enhance T cell activation., PMID:37813864
CUR-N399, a PI4KB inhibitor, for the treatment of Enterovirus A71 infection., PMID:37657668
Vemurafenib Inhibits Acute and Chronic Enterovirus Infection by Affecting Cellular Kinase Phosphatidylinositol 4-Kinase Type IIIβ., PMID:37436162
IFITM1 enhances nonenveloped viral RNA replication by facilitating cholesterol transport to the Golgi., PMID:37252940
The C10orf76-PI4KB axis orchestrates CERT-mediated ceramide trafficking to the distal Golgi., PMID:37195633
ARMH3-mediated recruitment of PI4KB directs Golgi-to-endosome trafficking and activation of the antiviral effector STING., PMID:36921576
PIP5K1C phosphoinositide kinase deficiency distinguishes PIKFYVE-dependent cancer cells from non-malignant cells., PMID:36803256
The m6A reader YTHDC1 regulates muscle stem cell proliferation via PI4K-Akt-mTOR signalling., PMID:36722312
A Novel Cuproptosis-Associated Gene Signature to Predict Prognosis in Patients with Pancreatic Cancer., PMID:36714025
Essential Domains of Oxysterol-Binding Protein Required for Poliovirus Replication., PMID:36560676
Omics analyses of a somatic Trp53R245W/+ breast cancer model identify cooperating driver events activating PI3K/AKT/mTOR signaling., PMID:36322759
Trans-ancestry, Bayesian meta-analysis discovers 20 novel risk loci for inflammatory bowel disease in an African American, East Asian and European cohort., PMID:36308435
ARFs get the BioID treatment: what have we been missing?, PMID:35929178
Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB., PMID:35844135
Molecular mechanisms of PI4K regulation and their involvement in viral replication., PMID:35579216
Cytoplasmic domain and enzymatic activity of ACE2 are not required for PI4KB dependent endocytosis entry of SARS-CoV-2 into host cells., PMID:35272059
Calcium-Prolactin Secretion Coupling in Rat Pituitary Lactotrophs Is Controlled by PI4-Kinase Alpha., PMID:35058881
Distinct APOL1 functions in trypanosomes and kidney podocytes., PMID:34887168
Clionamines stimulate autophagy, inhibit Mycobacterium tuberculosis survival in macrophages, and target Pik1., PMID:34520745
Establishment of a Ciliogenesis-Associated Signaling Model for Polycystic Kidney Disease., PMID:34469896
High-Order Epistasis and Functional Coupling of Infection Steps Drive Virus Evolution toward Independence from a Host Pathway., PMID:34468191
Novel Mechanism for an Old Drug: Phenazopyridine is a Kinase Inhibitor Affecting Autophagy and Cellular Differentiation., PMID:34421588
Curcumin Inhibits Replication of Human Parainfluenza Virus Type 3 by Affecting Viral Inclusion Body Formation., PMID:34409100
circSLC6A6 Sponges miR-497-5p to Promote Endometrial Cancer Progression via the PI4KB/Hedgehog Axis., PMID:34258297
ANXA2 Facilitates Enterovirus 71 Infection by Interacting with 3D Polymerase and PI4KB to Assist the Assembly of Replication Organelles., PMID:34196914
Phosphatidylinositol 4-kinase β is required for the ciliogenesis of zebrafish otic vesicle., PMID:33358778
The 14-3-3 Proteins as Important Allosteric Regulators of Protein Kinases., PMID:33233473
Myelination of peripheral nerves is controlled by PI4KB through regulation of Schwann cell Golgi function., PMID:33106410
The Mechanism of Kidney Disease Due to APOL1 Risk Variants., PMID:32943491
Drugging the Phosphoinositide 3-Kinase (PI3K) and Phosphatidylinositol 4-Kinase (PI4K) Family of Enzymes for Treatment of Cancer, Immune Disorders, and Viral/Parasitic Infections., PMID:32894512
APOL1 variant-associated kidney disease: from trypanosomes to podocyte cytoskeleton., PMID:32835731
Sub-fertility in crossbred bulls: deciphering testicular level transcriptomic alterations between zebu (Bos indicus) and crossbred (Bos taurus x Bos indicus) bulls., PMID:32693775
The function of apolipoproteins L (APOLs): relevance for kidney disease, neurotransmission disorders, cancer and viral infection., PMID:32530132
Puncta intended: connecting the dots between autophagy and cell stress networks., PMID:32507070
Emerging Role for Acyl-CoA Binding Domain Containing 3 at Membrane Contact Sites During Viral Infection., PMID:32322249
For research use only. Not for human or drug use.
