Catalog No.
YHN33601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser542-Ser722
Predicted molecular weight
22.29 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9HD20
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Endoplasmic reticulum P5A-ATPase, KIAA1825, ATP13A1, Endoplasmic reticulum transmembrane helix translocase, ATP13A
ATP13A1 engages SEC61 to facilitate substrate-specific translocation., PMID:40498833
Getting membrane proteins into shape., PMID:38759622
An ATP13A1-assisted topogenesis pathway for folding multi-spanning membrane proteins., PMID:38723633
Spf1 and Ste24: quality controllers of transmembrane protein topology in the eukaryotic cell., PMID:37635876
A genome-wide optical pooled screen reveals regulators of cellular antiviral responses., PMID:37043539
The effect of metal ions on the Spf1p P5A-ATPase. High sensitivity to irreversible inhibition by zinc., PMID:36328152
ATP13A1 prevents ERAD of folding-competent mislocalized and misoriented proteins., PMID:36283413
The Endoplasmic Reticulum ATP13A1 is Essential for MAVS-Mediated Antiviral Innate Immunity., PMID:36216581
Mitochondrial antiviral-signalling protein is a client of the BAG6 protein quality control complex., PMID:35543156
The P5-type ATPase ATP13A1 modulates major histocompatibility complex I-related protein 1 (MR1)-mediated antigen presentation., PMID:34968463
Transmembrane dislocases: a second chance for protein targeting., PMID:34147299
The Spf1p P5A-ATPase "arm-like" domain is not essential for ATP hydrolysis but its deletion impairs autophosphorylation., PMID:34087682
The endoplasmic reticulum P5A-ATPase is a transmembrane helix dislocase., PMID:32973005
Next generation sequencing exome data analysis aids in the discovery of SNP and INDEL patterns in Parkinson's disease., PMID:32348865
Parkinson disease related ATP13A2 evolved early in animal evolution., PMID:29505581
Expanding the genetic heterogeneity of intellectual disability., PMID:28940097
The Parkinson-associated human P5B-ATPase ATP13A2 protects against the iron-induced cytotoxicity., PMID:25912790
The yeast p5 type ATPase, spf1, regulates manganese transport into the endoplasmic reticulum., PMID:24392018
Developmental expression of P5 ATPase mRNA in the mouse., PMID:22207337
Characterization of the P5 subfamily of P-type transport ATPases in mice., PMID:15381061
For research use only. Not for human or drug use.
