Catalog No.
YHN33101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Cys243
Predicted molecular weight
30.42 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9H4Y5
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Glutathione-dependent dehydroascorbate reductase, Glutathione S-transferase omega 2-2, Monomethylarsonic acid reductase, Glutathione S-transferase omega-2, MMA(V) reductase, GSTO 2-2, GSTO2, GSTO-2
GSTP1 and GSTO1 Variant Alleles Affect Susceptibility to Helicobacter pylori Infection and Severity of Helicobacter pylori-Associated Clinical Manifestations., PMID:39859205
Responses of biological characteristics and detoxification enzymes in the fall armyworm to methoxyfenozide stress., PMID:39832257
Impaired striatal glutathione-ascorbate metabolism induces transient dopamine increase and motor dysfunction., PMID:39468205
GSTO2 ameliorates human neuroblastoma cell apoptosis, inflammation, ferroptosis, and oxidative stress by upregulating GPX4 expression in intracerebral hemorrhage., PMID:39154227
The Role of Glutathione Transferase Omega-Class Variant Alleles in Individual Susceptibility to Ovarian Cancer., PMID:38732205
Pivotal Role of GSTO2 in Ferroptotic Neuronal Injury After Intracerebral Hemorrhage., PMID:38386166
GPX3 Variant Genotype Affects the Risk of Developing Severe Forms of COVID-19., PMID:38003341
Decreased Klotho Expression Causes Accelerated Decline of Male Fecundity through Oxidative Injury in Murine Testis., PMID:37759974
Influence of genetic polymorphisms on arsenic methylation efficiency during pregnancy: Evidence from a Spanish birth cohort., PMID:37495132
The Polymorphisms in GSTO Genes (GSTO1 rs4925, GSTO2 rs156697, and GSTO2 rs2297235) Affect the Risk for Testicular Germ Cell Tumor Development: A Pilot Study., PMID:37374052
New insights into posttranslational modifications of proteins during bull sperm capacitation., PMID:37046330
Genome-Wide Splicing Quantitative Expression Locus Analysis Identifies Causal Risk Variants for Non-Small Cell Lung Cancer., PMID:36939399
Exome-based genome-wide screening of rare variants associated with the risk of polycystic ovary syndrome., PMID:36845002
Colonic mechanism of serum NAD+ depletion induced by DEHP during pregnancy., PMID:36781136
The Upregulation of GSTO2 is Associated with Colon Cancer Progression and a Poor Prognosis., PMID:36688005
The GSTO2 (rs156697) Polymorphism Modifies Diabetic Nephropathy Risk., PMID:36676788
Knockdown of glutathione S-transferase leads to mislocalization and accumulation of cabeza, a drosophila homolog of FUS, in the brain., PMID:36437507
Reduced oxidative stress suppresses neurotoxicity in the Drosophila model of TAF15-associated proteinopathies., PMID:36411469
Therapeutic modulation of GSTO activity rescues FUS-associated neurotoxicity via deglutathionylation in ALS disease models., PMID:35320731
Molecular characterization of a novel GSTO2 of Fasciola hepatica and its roles in modulating murine macrophages., PMID:35315767
Association of GSTO1, GSTO2, GSTP1, GPX1 and SOD2 polymorphism with primary open angle glaucoma., PMID:34826418
Loss of GSTO2 contributes to cell growth and mitochondria function via the p38 signaling in lung squamous cell carcinoma., PMID:34726807
Glutathione S-transferase Omega 2 DD genotype is associated with an increased risk of sporadic amyotrophic lateral sclerosis in Chinese men., PMID:34311603
Glutathione S-transferase gene polymorphic sequence variations: Association with risk and response to Imatinib among Chronic Myeloid Leukemia patients of Kashmir., PMID:33470551
Transcriptomic analysis of the effect of (E)-3-(3,5-dimethoxyphenyl)-1-(2-methoxyphenyl) prop-2-en-1-one (DPP23) on reactive oxygen species generation in MIA PaCa-2 pancreatic cancer cells., PMID:32949369
Glutathione S-Transferase Rescues Motor Neuronal Toxicity in Fly Model of Amyotrophic Lateral Sclerosis., PMID:32674363
As3MT and GST Polymorphisms Influencing Arsenic Metabolism in Human Exposure to Drinking Groundwater., PMID:32650499
Loci associated with genomic damage levels in chronic kidney disease patients and controls., PMID:32265040
Genetic Variants Associated with Chronic Kidney Disease in a Spanish Population., PMID:31924810
GSTO1*CC Genotype (rs4925) Predicts Shorter Survival in Clear Cell Renal Cell Carcinoma Male Patients., PMID:31861116
GSTO2 Isoforms Participate in the Oxidative Regulation of the Plasmalemma in Eutherian Spermatozoa during Capacitation., PMID:31795389
Glutathione S-transferase omega 2 regulates cell growth and the expression of E-cadherin via post-transcriptional down-regulation of β-catenin in human esophageal squamous cells., PMID:31738399
Sperm-borne glutathione-S-transferase omega 2 accelerates the nuclear decondensation of spermatozoa during fertilization in mice†., PMID:31087045
The perforatorium and postacrosomal sheath of rat spermatozoa share common developmental origins and protein constituents†., PMID:30939204
Gene-environment interaction and maternal arsenic methylation efficiency during pregnancy., PMID:30703610
Association analysis of Glutathione S-transferase omega-1 and omega-2 genetic polymorphisms and ischemic stroke risk in a Turkish population., PMID:30417762
Levels of DNA damage (Micronuclei) in patients suffering from chronic kidney disease. Role of GST polymorphisms., PMID:30389161
Concomitance of Polymorphisms in Glutathione Transferase Omega Genes Is Associated with Risk of Clear Cell Renal Cell Carcinoma., PMID:30224590
Influence of all-trans retinoic acid on sperm metabolism and oxidative stress: Its involvement in the physiopathology of varicocele-associated male infertility., PMID:29943815
Association between arsenic metabolism gene polymorphisms and arsenic-induced skin lesions in individuals exposed to high-dose inorganic arsenic in northwest China., PMID:29323258
Sodium butyrate enhanced physical barrier function referring to Nrf2, JNK and MLCK signaling pathways in the intestine of young grass carp (Ctenopharyngodon idella)., PMID:29222028
Investigating the therapeutic potential and mechanism of curcumin in breast cancer based on RNA sequencing and bioinformatics analysis., PMID:29139094
Effects of Nrf2 deficiency on arsenic metabolism in mice., PMID:29108910
The developmental origin and compartmentalization of glutathione-s-transferase omega 2 isoforms in the perinuclear theca of eutherian spermatozoa., PMID:29036365
Association of GSTO1 A140D and GSTO2 N142D Gene Variations with Breast Cancer Risk., PMID:28670895
Association of GSTO1 and GSTO2 Polymorphism with Risk of End-Stage Renal Disease Development and Patient Survival., PMID:28356881
Association of glutathione S-transferase omega polymorphism and spinocerebellar ataxia type 2., PMID:28017238
Distribution of Glutathione S-Transferase Omega Gene Polymorphism with Different Stages of HBV Infection Including Hepatocellular Carcinoma in the Egyptian Population., PMID:27221910
Functional and mutational analyses of an omega-class glutathione S-transferase (GSTO2) that is required for reducing oxidative damage in Apis cerana cerana., PMID:27170478
Structure, function and disease relevance of Omega-class glutathione transferases., PMID:26993125
For research use only. Not for human or drug use.
