Catalog No.
YHJ52502
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser304-Pro431
Predicted molecular weight
27.75 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9BZS1
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Forkhead box protein P3, IPEX, Scurfin, FOXP3
Chronic administration of morphine provokes generation of antibodies to morphine and immunosuppression in individuals with opioid use disorder., PMID:40501089
Experimental autoimmune encephalomyelitis impairs the immunomodulatory effects of mesenchymal stem cells on splenocyte responses., PMID:40498218
Immunomodulatory potential of Toxoplasma gondii lysate in C57BL/6 mouse model of autoimmune encephalomyelitis., PMID:40498142
Expression of the Transcription Factor FOXP3 in Human Peripheral Blood B-Cell Subtypes (CD19+CD39+ and CD19+CD39-) and Evaluation of Their Regulatory Function., PMID:40497715
Increase of CD4+CD25+FoxP3+Regulatory T Cells in Myeloma., PMID:40497604
FOXP3+ Macrophage-Derived Amphiregulin Promotes White Matter Repair of Experimental Autoimmune Encephalomyelitis., PMID:40497405
The T follicular helper/T follicular helper regulatory pathway in FVIII immune responses in mice., PMID:40493881
Insights into Keratinocyte and Immunologic Landscape in Cutaneous Graft-Versus-Host Disease through Single-Cell Transcriptomics., PMID:40492027
Harnessing the Power of Chlorogenic Acid: Inhibiting IL-2-Mediated Treg Upregulation to Combat Post-Traumatic Osteomyelitis., PMID:40485518
Inducible protein degradation reveals inflammation-dependent function of the Treg cell lineage-defining transcription factor Foxp3., PMID:40478934
ALG3 as a prognostic biomarker and mediator of PD-1 blockade resistance in hepatocellular carcinoma., PMID:40475760
STAT3 inhibition mitigates experimental autoimmune gastritis by restoring Th17/Treg immune balance., PMID:40471463
Temporal and Context-Dependent Requirements for the Transcription Factor Foxp3 Expression in Regulatory T Cells., PMID:40470210
Single-cell RNA sequencing analysis reveals a lack of CXCL13+ T cell subsets associated with the recurrence of cervical squamous cell carcinoma following concurrent chemoradiotherapy., PMID:40464813
Associations among IL-6 Signaling Molecules in Treg Populations in Patients with Relapsing-Remitting Multiple Sclerosis., PMID:40464469
Akkermansia Muciniphila Alleviates Severe Acute Pancreatitis via Amuc1409-Ube2k-Foxp3 Axis in Regulatory T Cells., PMID:40464424
Succinate drives gut inflammation by promoting FOXP3 degradation through a molecular switch., PMID:40457062
Black Death protective gene mutation shows ambiguous role in type 1 diabetes, its complications, and common viral infections., PMID:40449626
Functional Delivery Systems for Targeting Tumor Heterogeneity: Reversing Immunosuppression and Modulating Cancer-Immune Interplay., PMID:40448637
The effect of CTLA4-Ig on fibrotic progression in a murine model of chronic lung allograft dysfunction., PMID:40446880
Ovalbumin-specific regulatory T cells differentiated from the naïve phenotype (CD44loCD62Lhi) in mesenteric lymph nodes stably suppress enteropathy even in severe food-allergic mice., PMID:40446078
Study on the mechanism by which Xuanfu Hua Tang increases sensitivity of hepatocellular carcinoma cells to sorafenib by antagonizing the Notch1 pathway through HIF-2α., PMID:40444091
Identification and validation of pyroptosis-related genes in Alzheimer's disease based on multi-transcriptome and machine learning., PMID:40438507
N-glycosylated LTβR increases the Th17/Treg cell ratio in liver cancer by blocking RORC ubiquitination and FOXP3 transcription., PMID:40436857
Intranasal Application of Foxp3 Introduced with Poly(d,l-lactic-co-glycolic acid) (PLGA) Nanoparticles (Foxp3 NPs) Attenuates Allergic Inflammation in a Mouse Model of Allergic Rhinitis., PMID:40430867
Astragalus Extract Mixture HT042 Reverses Cyclophosphamide-Induced Immunosuppression Through Dual Modulation of Innate and Adaptive Immunity., PMID:40429990
A Case of Complete Response to ICI Therapy for Unresectable Esophageal Squamous Cell Carcinoma., PMID:40425339
The Spatial Proximity of CD8+ FoxP3+PD-1+ Cells to Tumor Cells: A More Accurate Predictor of Immunotherapy Outcomes in Advanced Non-Small-Cell Lung Cancer., PMID:40422521
[Zfp335 regulates the proportion of effector Treg and tumor immunity]., PMID:40415616
Rapamycin-modified CD169low/-tolDC promotes skin graft survival in mice via IL-10+Breg., PMID:40414462
Rejuvenation of thymus and modulation of local and systemic T cell responses in animal model of Alzheimer's disease following cell therapy using sperm head., PMID:40409106
Streptococcal pyrogenic exotoxin a induces regulatory T cells via TNF-α-TNFR2 signaling., PMID:40402252
Osteopontin protects from ovalbumin-induced asthma by preserving the microbiome and the intestinal barrier function., PMID:40401951
Effects of Yoga on Gene Expression: A Systematic Review of Randomised Controlled Trials., PMID:40400827
An immune-based predictive model for HBV clearance: validation in multicenter cohorts and mechanistic insights from in vivo studies., PMID:40399947
Distribution of two CD4+FOXP3+ T cell subpopulations reflects disease phenotypes and prognosis in COPD., PMID:40399434
Mechanisms of LouDan LiFei granule attenuate inflammatory injury in AECOPD:A network pharmacology and experimental validation., PMID:40397998
Adaptive immune response and PD-1/ PD-L1 status in chemotherapy treated high grade serous carcinoma is dependent on chemotherapy response score., PMID:40389122
Identification of MAGE-A10 specific T cell receptor promising in immunotherapy of hepatocellular carcinoma., PMID:40379175
Tyrosinase in melanoma inhibits anti-tumor activity of PD-1 deficient T cells., PMID:40375241
Targeting Setdb1 in T cells induces transplant tolerance without compromising antitumor immunity., PMID:40374612
The immune tolerance role of Bregs in inhibiting human inflammatory diseases, with a focus on diabetes mellitus., PMID:40370441
Diagnostic Accuracy of Serum P16ink4A and FOX-P3 Concentrations for Detection of Cervical Lesions Among Women Attending a Cervical Cancer Clinic in Western Uganda: A Case-Control Study., PMID:40365511
Development and Potent Anti-Tumor Activity of a Fully Humanized Anti-TAG-72-IL-2 Fusion Protein for Therapy of Solid Tumors., PMID:40361381
Low IL-35 expression in CSF is associated with Neuro-Behcet Disease: Comparative analysis between parenchymal and Non-parenchymal NBD., PMID:40360083
Modulation of immune responses induced by recombinant BCG expressing LTAK63 adjuvant in an immunotherapeutic model vaccine., PMID:40359816
IDO can improve ovarian function in premature ovarian insufficiency via AhR and regulatory T cells., PMID:40358004
Independent and temporally separated dynamics for RORγt and Foxp3 during Th17 differentiation., PMID:40356912
Oncolytic reovirus enhances the effect of CEA immunotherapy when combined with PD1-PDL1 inhibitor in a colorectal cancer model., PMID:40353308
Effects of traditional music therapy on the psycho-neuro-immuno-endocrine aspect of burnout syndrome in healthcare workers: A randomized controlled trial., PMID:40352215