Catalog No.
YHN32501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu38-Gly146
Predicted molecular weight
14.79 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9BVK6
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Glycoprotein 25L2, GP25L2, p24alpha2, GMP25, p24 family protein alpha-2, p25, Transmembrane emp24 domain-containing protein 9, TMED9
Targeting the Cargo Receptor TMED9 as a Therapeutic Strategy Against Brain Tumors., PMID:40497947
TMED9 coordinates the clearance of misfolded GPI-anchored proteins out of the ER and into the Golgi., PMID:40203033
TMED9 coordinates the clearance of misfolded GPI-anchored proteins out of the endoplasmic reticulum and into the Golgi., PMID:39974996
A Proteomic Examination of Plasma Extracellular Vesicles Across Colorectal Cancer Stages Uncovers Biological Insights That Potentially Improve Prognosis., PMID:39766158
Disrupted uromodulin trafficking is rescued by targeting TMED cargo receptors., PMID:39680459
Prognostic value and anti-tumor immunity role of TMED9 in pan-cancer: a bioinformatics study., PMID:39525003
Molecular basis of TMED9 oligomerization and entrapment of misfolded protein cargo in the early secretory pathway., PMID:39303030
Quantitative proteomics of patient fibroblasts reveal biomarkers and diagnostic signatures of mitochondrial disease., PMID:39288270
Integrative Multi-Omics Analysis Identifies Transmembrane p24 Trafficking Protein 1 (TMED1) as a Potential Prognostic Marker in Colorectal Cancer., PMID:38392302
The p24-family and COPII subunit SEC24C facilitate the clearance of alpha1-antitrypsin Z from the endoplasmic reticulum to lysosomes., PMID:38294851
The many hats of transmembrane emp24 domain protein TMED9 in secretory pathway homeostasis., PMID:36733337
TMED9 Expression Level as a Biomarker of Epithelial Ovarian Cancer Progression and Prognosis., PMID:36316042
TMED3 Complex Mediates ER Stress-Associated Secretion of CFTR, Pendrin, and SARS-CoV-2 Spike., PMID:35748162
High expression of transmembrane P24 trafficking protein 9 predicts poor prognosis in breast carcinoma., PMID:34635011
A new type of ERGIC-ERES membrane contact mediated by TMED9 and SEC12 is required for autophagosome biogenesis., PMID:34561617
miR-802 regulates Paneth cell function and enterocyte differentiation in the mouse small intestine., PMID:34099655
Proteomics-based identification of TMED9 is linked to vascular invasion and poor prognoses in patients with hepatocellular carcinoma., PMID:33888099
BPIFB3 interacts with ARFGAP1 and TMED9 to regulate non-canonical autophagy and RNA virus infection., PMID:33277377
Small Molecule Targets TMED9 and Promotes Lysosomal Degradation to Reverse Proteinopathy., PMID:31348885
The protein secretion modulator TMED9 drives CNIH4/TGFα/GLI signaling opposing TMED3-WNT-TCF to promote colon cancer metastases., PMID:31253868
Transgene-associated human growth hormone expression in pancreatic β-cells impairs identification of sex-based gene expression differences., PMID:30532991
Comparative transcriptome analysis reveals a regulatory network of microRNA-29b during mouse early embryonic development., PMID:27449102
MicroRNAs 296 and 298 are imprinted and part of the GNAS/Gnas cluster and miR-296 targets IKBKE and Tmed9., PMID:22114321
For research use only. Not for human or drug use.
