Catalog No.
YHN31801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser119-Ser268
Predicted molecular weight
18.91 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q99618
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
C8, TOME-1, CDCA3, GRCC8, Trigger of mitotic entry protein 1, Cell division cycle-associated protein 3, Gene-rich cluster protein C8, TOME1
A comprehensive review and in silico analysis of the role of survivin (BIRC5) in hepatocellular carcinoma hallmarks: A step toward precision., PMID:40306500
Circ_0035381 contributes to the progression of acute myeloid leukemia via regulating miR-186-5p/CDCA3 pathway., PMID:40205799
miR-145-5p modulates CDCA3 to overcome gemcitabine resistance in pancreatic cancer., PMID:40116423
CDCA3-MYC positive feedback loop promotes bladder cancer progression via ENO1-mediated glycolysis., PMID:39980052
CDCA genes as prognostic and therapeutic targets in Colon adenocarcinoma., PMID:39924497
The High-Affinity IL-2 Receptor Affects White Matter Damage after Cerebral Ischemia by Regulating CD8 + T Lymphocyte Differentiation., PMID:39821696
Roles of the CDCA gene family in breast carcinoma., PMID:39814554
Transcriptional analysis reveals the suppression of RAD51 and disruption of the homologous recombination pathway during PEDV infection in IPEC-J2 cells., PMID:39731192
Identifying CDCA3 as a pivotal biomarker for predicting outcomes and immunotherapy efficacy in pan-renal cell carcinoma., PMID:39434731
Comprehensive analysis of aberrantly methylated differentially expressed genes and validation of CDC6 in melanoma., PMID:39052109
Comprehensive bioinformatics analysis and cell line experiments revealed the important role of CDCA3 in sarcoma., PMID:39035484
The shared mechanism and potential diagnostic markers for premature ovarian failure and dry eye disease., PMID:39003404
Finding key genes (UBE2T, KIF4A, CDCA3, and CDCA5) co-expressed in hepatitis, cirrhosis and hepatocellular carcinoma based on multiple bioinformatics techniques., PMID:38890649
CDCA3 is a potential biomarker for glioma malignancy and targeted therapy., PMID:38728485
Downregulation of PTPRT elevates the expression of survivin and promotes the proliferation, migration, and invasion of lung adenocarcinoma., PMID:38216925
Genome-wide DNA methylation of lesional and peri-lesional skin in vitiligo: a comparative and integrated analysis of multi-omics in Chinese population., PMID:38182908
Integrated bioinformatics analysis and experimental validation identified CDCA families as prognostic biomarkers and sensitive indicators for rapamycin treatment of glioma., PMID:38181024
Pyroptosis-Related Subtypes Predict the Response of Clear Cell Renal Cell Carcinoma to Targeted Therapy., PMID:38179741
Origin recognition complex subunit 1(ORC1) is a potential biomarker and therapeutic target in cancer., PMID:37833711
Prognostic value of cell division cycle-associated protein-3 in prostate cancer., PMID:37682152
Modifications of The Human Liver Cancer Cells through microRNA-145-Mediated Targeting of CDCA3., PMID:37641416
Identification of circ_0038632 as a Promoter of Breast Cancer through miR-520a-3p-Dependent Modulation of CDCA3., PMID:37625824
[Retracted] KIF22 promotes bladder cancer progression by activating the expression of CDCA3., PMID:37615186
Retracted: Cell Division Cycle-Associated Protein 3 (CDCA3) Is a Potential Biomarker for Clinical Prognosis and Immunotherapy in Pan-Cancer., PMID:37388379
Curcumin targets miR-134-5p to suppress the progression of colorectal cancer through regulating the CDCA3/CDK1 pathway., PMID:37368030
LncRNA landscape and associated ceRNA network in placental villus of unexplained recurrent spontaneous abortion., PMID:37340405
[Retracted] KIF4A promotes the development of bladder cancer by transcriptionally activating the expression of CDCA3., PMID:37293853
Glycolysis in human cancers: Emphasis circRNA/glycolysis axis and nanoparticles in glycolysis regulation in cancer therapy., PMID:37119844
Bioinformatic analysis highlights SNHG6 as a putative prognostic biomarker for kidney renal papillary cell carcinoma., PMID:37004005
CDCA3 promotes the proliferation and migration of hypopharyngeal squamous cell carcinoma cells by activating the Akt/mTOR pathway., PMID:36892980
Structural investigation of CDCA3-Cdh1 protein-protein interactions using in vitro studies and molecular dynamics simulation., PMID:36691744
Identification of molecular subtypes based on chromatin regulator and tumor microenvironment infiltration characterization in papillary renal cell carcinoma., PMID:36404389
Pan-cancer analysis identifies CDCA3 as a novel prognostic marker associated with immune infiltration in lung adenocarcinoma through bioinformatics analysis., PMID:36093552
MiRNA-144-5p down-modulates CDCA3 to regulate proliferation and apoptosis of lung adenocarcinoma cells., PMID:36087462
Cell Division Cycle-Associated Protein 3 (CDCA3) Is a Potential Biomarker for Clinical Prognosis and Immunotherapy in Pan-Cancer., PMID:36082153
CDCA3 exhibits a role in promoting the progression of ovarian cancer., PMID:36081320
MYBL2 promotes proliferation and metastasis of bladder cancer through transactivation of CDCA3., PMID:36071275
Lamin B2 contributes to the proliferation of bladder cancer cells via activating the expression of cell division cycle‑associated protein 3., PMID:35775376
Long noncoding RNA ST8SIA6-AS1 promotes cell proliferation and metastasis in triple-negative breast cancer by targeting miR-145-5p/CDCA3 to inactivate the p53/p21 signaling pathway., PMID:35730485
LncCDCA3L inhibits cell proliferation via a novel RNA structure-based crosstalk with CDCA3 in hepatocellular carcinoma., PMID:35230745
Network meta-analysis of transcriptome expression changes in different manifestations of dengue virus infection., PMID:35220956
TRIM39 is a poor prognostic factor for patients with estrogen receptor-positive breast cancer and promotes cell cycle progression., PMID:35174936
Bioinformatics analysis of the clinical relevance of CDCA gene family in prostate cancer., PMID:35119046
Suppression of CDCA3 inhibits prostate cancer progression via NF‑κB/cyclin D1 signaling inactivation and p21 accumulation., PMID:34970697
Prognostic value of CDCA3 in kidney renal papillary cell carcinoma., PMID:34905505
Analysis and verification of N6-methyladenosine-modified genes as novel biomarkers for clear cell renal cell carcinoma., PMID:34699322
KIF22 promotes bladder cancer progression by activating the expression of CDCA3., PMID:34633053
Bioinformatic Analysis for Influential Core Gene Identification and Prognostic Significance in Advanced Serous Ovarian Carcinoma., PMID:34577856
Elevating CDCA3 Levels Enhances Tyrosine Kinase Inhibitor Sensitivity in TKI-Resistant EGFR Mutant Non-Small-Cell Lung Cancer., PMID:34572879
[SCP Phosphatases and Oncogenesis]., PMID:34432772
For research use only. Not for human or drug use.
