Catalog No.
YHN31401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala2-Glu103
Predicted molecular weight
25.46 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q99417
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MYCBP, AMY-1, AMY1, Associate of Myc 1, c-Myc-binding protein
USP25-driven KIFC1 regulates MYCBP expression and promotes the progression of cervical cancer., PMID:40379626
Bourbon and Mycbp function with Otu to promote Sxl protein expression in the Drosophila female germline., PMID:40215271
Bioinformatics-Guided Identification and Quantification of Biomarkers of Crotalus atrox Envenoming and Its Neutralization by Antivenom., PMID:40147718
Microrna-342 inhibits hepatocellular carcinoma cell proliferation and promotes apoptosis through the FOXP1/MYCBP Signaling Axis., PMID:39698396
Upregulation of the long noncoding RNA GJA9-MYCBP and PVT1 is a potential diagnostic biomarker for acute lymphoblastic leukemia., PMID:38994720
Circ_0002669 promotes osteosarcoma tumorigenesis through directly binding to MYCBP and sponging miR-889-3p., PMID:38570856
Novel MYCBP::EHD2 and RUNX1::ZNF780A Fusion Genes in T-cell Acute Lymphoblastic Leukemia., PMID:36581344
Downregulation of hsa-miR-135b-5p Inhibits Cell Proliferation, Migration, and Invasion in Colon Adenocarcinoma., PMID:36407085
Downregulated RRS1 inhibits invasion and metastasis of BT549 through RPL11‑c‑Myc‑SNAIL axis., PMID:35179222
Verdinexor, a Selective Inhibitor of Nuclear Exportin 1, Inhibits the Proliferation and Migration of Esophageal Cancer via XPO1/c-Myc/FOSL1 Axis., PMID:34975332
MiR-26b-5p inhibits cell proliferation and EMT by targeting MYCBP in triple-negative breast cancer., PMID:34895159
Lysine Demethylase 6B Regulates Prostate Cancer Cell Proliferation by Controlling c-MYC Expression., PMID:34862309
USP28 deletion and small-molecule inhibition destabilizes c-MYC and elicits regression of squamous cell lung carcinoma., PMID:34636321
Immunohistochemical signaling pathways of triple negative and triple positive breast cancers: What is new?, PMID:34634762
Involvement of c-Myc in low dose radiation-induced senescence enhanced migration and invasion of unirradiated cancer cells., PMID:34552037
Downregulation of miR-23b by transcription factor c-Myc alleviates ischemic brain injury by upregulating Nrf2., PMID:34512173
TAZ is indispensable for c-MYC-induced hepatocarcinogenesis., PMID:34464659
Dietary carbohydrates interact with AMY1 polymorphisms to influence the incidence of type 2 diabetes in Korean adults., PMID:34408213
FBP1 regulates proliferation, metastasis, and chemoresistance by participating in C-MYC/STAT3 signaling axis in ovarian cancer., PMID:34363022
The Long Noncoding RNA LINC00665 Facilitates c-Myc Transcriptional Activity via the miR-195-5p MYCBP Axis to Promote Progression of Lung Adenocarcinoma., PMID:34277412
Chlamydomonas FAP70 is a component of the previously uncharacterized ciliary central apparatus projection C2a., PMID:33988244
Downregulation of c-Myc expression confers sensitivity to CHK1 inhibitors in hematologic malignancies., PMID:33782542
DUBR suppresses migration and invasion of human lung adenocarcinoma cells via ZBTB11-mediated inhibition of oxidative phosphorylation., PMID:33758355
Metabolic sensor O-GlcNAcylation regulates megakaryopoiesis and thrombopoiesis through c-Myc stabilization and integrin perturbation., PMID:33544938
Cardiac myosin-binding protein C in the diagnosis and risk stratification of acute heart failure., PMID:33421273
lncRNA LUNAR1 accelerates colorectal cancer progression by targeting the miR‑495‑3p/MYCBP axis., PMID:33300052
The association of Plk1 with the astrin-kinastrin complex promotes formation and maintenance of a metaphase plate., PMID:33288550
The therapeutic potential of exosomal miR-22 for cervical cancer radiotherapy., PMID:33190594
A small-sized benzothiazole-indolium fluorescent probe: the study of interaction specificity targeting c-MYC promoter G-quadruplex structures and live cell imaging., PMID:33185205
LncRNA MNX1-AS1 promotes progression of intrahepatic cholangiocarcinoma through the MNX1/Hippo axis., PMID:33093444
High plasma salivary α-amylase, but not high AMY1 copy number, associated with low obesity rate in Qatari adults: cross-sectional study., PMID:33087771
To probe the binding pathway of a selective compound (D089-0563) to c-MYC Pu24 G-quadruplex using free ligand binding simulations and Markov state model analysis., PMID:33000836
Good or not good: Role of miR-18a in cancer biology., PMID:32884453
Matrine inhibits the growth of natural killer/T-cell lymphoma cells by modulating CaMKIIγ-c-Myc signaling pathway., PMID:32641029
Patients with double/triple copy number gains on C-MYC, BCL2, and/or BCL6 treated with standard chemotherapy have a similarly poor prognosis than those with high-grade B cell lymphoma with C-MYC and BCL2 and/or BCL6 rearrangements: a single-center experience on a consecutive cohort of large B cell lymphomas., PMID:32613279
Colon adenocarcinoma-derived cells that express induced-pluripotent stem cell markers possess stem cell function., PMID:32428045
Autophagy in the physiological endometrium and cancer., PMID:32401642
Classifying DLBCL according cell of origin using Hans algorithm and its association with clinicopathological parameters: A single centre experience., PMID:32281588
Activation of notch 3/c-MYC/CHOP axis regulates apoptosis and promotes sensitivity of lung cancer cells to mTOR inhibitor everolimus., PMID:32201213
MicroRNA-22 enhances radiosensitivity in cervical cancer cell lines via direct inhibition of c-Myc binding protein, and the subsequent reduction in hTERT expression., PMID:32194719
Intermediate Standstill Clones Trapped in the Reprogramming of Human Fibroblasts to Induced Pluripotent Stem Cells., PMID:32182120
MiR-451a attenuates doxorubicin resistance in lung cancer via suppressing epithelialmesenchymal transition (EMT) through targeting c-Myc., PMID:32106373
The c-Myc/miR-27b-3p/ATG10 regulatory axis regulates chemoresistance in colorectal cancer., PMID:32104496
PLA2G4A Is a Potential Biomarker Predicting Shorter Overall Survival in Patients with Non-M3/NPM1 Wildtype Acute Myeloid Leukemia., PMID:32077754
C-Myc inhibition sensitizes pre-B ALL cells to the anti-tumor effect of vincristine by altering apoptosis and autophagy: Proposing a probable mechanism of action for 10058-F4., PMID:31770526
Inhibition of PI3K pathway using BKM120 intensified the chemo-sensitivity of breast cancer cells to arsenic trioxide (ATO)., PMID:31539632
EYA4 inhibits hepatocellular carcinoma by repressing MYCBP by dephosphorylating β-catenin at Ser552., PMID:31385398
Deubiquitylatinase inhibitor b-AP15 induces c-Myc-Noxa-mediated apoptosis in esophageal squamous cell carcinoma., PMID:31342239
LncRNA MIR22HG abrogation inhibits proliferation and induces apoptosis in esophageal adenocarcinoma cells via activation of the STAT3/c-Myc/FAK signaling., PMID:31291201
Crystal Structures and Nuclear Magnetic Resonance Studies of the Apo Form of the c-MYC:MAX bHLHZip Complex Reveal a Helical Basic Region in the Absence of DNA., PMID:31260268
For research use only. Not for human or drug use.
