Catalog No.
YHN30801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln344-Gln462
Predicted molecular weight
15.79 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q96EZ8
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MCRS1, INO80 complex subunit J, Microspherule protein 1, MCRS2, Cell cycle-regulated factor p78, INO80Q, MSP58, 58 kDa microspherule protein
The Arabidopsis homolog of microspherule protein 1 is essential for embryogenesis and interacts with the Myb-like transcription factor DRMY1., PMID:40317227
MCRS1 sensitizes T cell-dependent immunotherapy by augmenting MHC-I expression in solid tumors., PMID:39545935
RBCK1 overexpression is associated with immune cell infiltration and poor prognosis in hepatocellular carcinoma., PMID:38214606
Unreprogrammed H3K9me3 prevents minor zygotic genome activation and lineage commitment in SCNT embryos., PMID:37558707
Orphan quality control shapes network dynamics and gene expression., PMID:37478862
Mcrs1 regulates G2/M transition and spindle assembly during mouse oocyte meiosis., PMID:36951681
Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance., PMID:36652375
The molecular characteristics and functional roles of microspherule protein 1 (MCRS1) in gene expression, cell proliferation, and organismic development., PMID:36384428
MCRS1 modulates the heterogeneity of microtubule minus-end morphologies in mitotic spindles., PMID:36350698
MCRS1 Expression Regulates Tumor Activity and Affects Survival Probability of Patients with Gastric Cancer., PMID:35741311
Mcrs1 is required for branchial arch and cranial cartilage development., PMID:35697116
Histone acetylation of bile acid transporter genes plays a critical role in cirrhosis., PMID:34958836
MYCN and MAX alterations in Wilms tumor and identification of novel N-MYC interaction partners as biomarker candidates., PMID:34689785
Mcrs1 interacts with Six1 to influence early craniofacial and otic development., PMID:32891623
Expression of Rta in B Lymphocytes during Epstein-Barr Virus Latency., PMID:32710985
MCRS1 is essential for epiblast development during early mouse embryogenesis., PMID:31671403
RNAi-mediated depletion of the NSL complex subunits leads to abnormal chromosome segregation and defective centrosome duplication in Drosophila mitosis., PMID:31527906
miR-186 modulates hepatocellular carcinoma cell proliferation and mobility via targeting MCRS1-mediated Wnt/β-catenin signaling., PMID:31140612
Effects of MCRS1 on proliferation, migration, invasion, and epithelial mesenchymal transition of gastric cancer cells by interacting with Pkmyt1 protein kinase., PMID:30953699
Mps1 regulates spindle morphology through MCRS1 to promote chromosome alignment., PMID:30785839
A candidate gene identification strategy utilizing mouse to human big-data mining: "3R-tenet" in COPD genetic research., PMID:29871630
Identification of Two Distinct Classes of the Human INO80 Complex Genome-Wide., PMID:29432129
mTORC1 Inactivation Promotes Colitis-Induced Colorectal Cancer but Protects from APC Loss-Dependent Tumorigenesis., PMID:29275959
Knockdown of MSP58 inhibits the proliferation and metastasis in human renal cell carcinoma cells., PMID:28448870
miRNA-129-5p suppresses cell proliferation and invasion in lung cancer by targeting microspherule protein 1, E-cadherin and vimentin., PMID:28105223
RINT-1 interacts with MSP58 within nucleoli and plays a role in ribosomal gene transcription., PMID:27530925
MCRS1: Not only ran., PMID:27485672
Increased Expression of 58-kDa Microspherule Protein (MSP58) in Human Gastric Cancer Promotes Cell Proliferation and Correlates with Poor Patient Survival., PMID:27468560
Expression of MCRS1 and MCRS2 and their correlation with serum carcinoembryonic antigen in colorectal cancer., PMID:27446248
Spatiotemporal Reconstruction of the Human Blastocyst by Single-Cell Gene-Expression Analysis Informs Induction of Naive Pluripotency., PMID:27404362
MCRS1 associates with cytoplasmic dynein and mediates pericentrosomal material recruitment., PMID:27263857
Aurora-A regulates MCRS1 function during mitosis., PMID:27192185
Expression of 58-kD Microspherule Protein (MSP58) is Highly Correlated with PET Imaging of Tumor Malignancy and Cell Proliferation in Glioma Patients., PMID:26849376
Transport to Rhebpress activity., PMID:26735067
Searching for candidate genes in familial BRCAX mutation carriers with prostate cancer., PMID:26585945
The candidate oncogene (MCRS1) promotes the growth of human lung cancer cells via the miR-155-Rb1 pathway., PMID:26467212
Stabilization of MCRS1 by BAP1 prevents chromosome instability in renal cell carcinoma., PMID:26300492
Coning phenomena under laminar flow., PMID:26296866
Identification and characterization of nuclear and nucleolar localization signals in 58-kDa microspherule protein (MSP58)., PMID:25981436
MCRS1 binds and couples Rheb to amino acid-dependent mTORC1 activation., PMID:25816988
MCRS1 overexpression, which is specifically inhibited by miR-129*, promotes the epithelial-mesenchymal transition and metastasis in non-small cell lung cancer., PMID:25373388
The 58-kda microspherule protein (MSP58) represses human telomerase reverse transcriptase (hTERT) gene expression and cell proliferation by interacting with telomerase transcriptional element-interacting factor (TEIF)., PMID:24361335
Increased expression of the 58-kD microspherule protein (MSP58) is correlated with poor prognosis in glioma patients., PMID:23996240
Expression of MSP58 in hepatocellular carcinoma., PMID:23519485
Analysis of 20 genes at chromosome band 12q13: RACGAP1 and MCRS1 overexpression in nonsmall-cell lung cancer., PMID:23225332
The novel interaction between microspherule protein Msp58 and ubiquitin E3 ligase EDD regulates cell cycle progression., PMID:23069210
MSP58 knockdown inhibits the proliferation of esophageal squamous cell carcinoma in vitro and in vivo., PMID:22994740
Downregulation of MSP58 suppresses cell proliferation in neuroblastoma cell lines., PMID:22975844
Expression of MSP58 in human colorectal cancer and its correlation with prognosis., PMID:22773039
Microspherule protein 2 associates with ASK1 and acts as a negative regulator of stress-induced ASK1 activation., PMID:22609355
For research use only. Not for human or drug use.
