Catalog No.
YHN30001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser141-Gly367
Predicted molecular weight
28.51 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q96AV8
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
E2F7, Transcription factor E2F7, E2F-7
Large Yellow Croaker (Pseudosciaena crocea, Richardson) E2F4, a Cyclin-Dependent Transcription Factor, Forms a Heterodimer with DP1., PMID:40508152
Functional Analysis and Clinical Significance of Glutaredoxin 2 in Colon Cancer., PMID:40471359
Bioinformatics and system biology approach to discover the common pathogenetic processes between COVID-19 and chronic hepatitis B., PMID:40408617
Suppression of pseudogene MT2P1 transcription induced by E2F7 inhibits hepatocellular carcinoma cell proliferation and facilitates apoptosis via preserving its parental gene., PMID:40407049
PRMT1 Upregulates SIRT6 by Enhancing Arginine Methylation of E2F7 to Inhibit Vascular Smooth Muscle Cell Senescence in Aortic Dissection., PMID:40298071
FOXO1 mediates miR-99a-5p/E2F7 to restrain breast cancer cell proliferation and induce apoptosis., PMID:40264026
E2F7 upregulates MCM4 and fatty acid metabolism to advance lung adenocarcinoma metastasis., PMID:40158794
Ascending E2F7a/b ratio facilitates KLF13 transcription in hepatocellular carcinoma and correlates with the abundance of binuclear hepatocytes (ABH) modulation for short-term recurrence., PMID:40116212
Cdk1 and PP2A constitute a molecular switch controlling orderly degradation of atypical E2Fs., PMID:40027684
EFL-3/E2F7 modulates Wnt signalling by repressing the Nemo-like kinase LIT-1 during asymmetric epidermal cell division in Caenorhabditis elegans., PMID:40026193
Screening of common genomic biomarkers to explore common drugs for the treatment of pancreatic and kidney cancers with type-2 diabetes through bioinformatics analysis., PMID:40025145
Integrated genomic analysis of the stemness index signature of mRNA expression predicts lung adenocarcinoma prognosis and immune landscape., PMID:39959839
E2F1 and E2F7 regulate gastric cancer cell proliferation, respectively, through transcriptional activation and transcriptional repression of MYBL2., PMID:39613162
Study of the Role of E2F1 and TMEM132A in Prostate Cancer Development., PMID:39473405
Dysregulated inclusion of BOLA3 exon 3 promoted by HNRNPC accelerates the progression of esophageal squamous cell carcinoma., PMID:39455467
miR-195-5p inhibits cisplatin resistance in lung adenocarcinoma by regulating DNA damage via targeting E2F7., PMID:39415701
The novel circFKBP8/miR-432-5p/E2F7 cascade functions as a regulatory network in breast cancer., PMID:39192374
Analysis of translesion polymerases in colorectal cancer cells following cetuximab treatment: A network perspective., PMID:39102671
Identification of new targets for glioblastoma therapy based on a DNA expression microarray., PMID:38981212
The predictive value of E2F7 in immunotherapy efficacy for lung adenocarcinoma: An observational study., PMID:38905387
An alternative cell cycle coordinates multiciliated cell differentiation., PMID:38811726
Coptisine-mediated downregulation of E2F7 induces G2/M phase arrest in hepatocellular carcinoma cells through inhibition of E2F4/NFYA/NFYB transcription factors., PMID:38795876
An E2F7/TSC1-based model for predicting the efficacy of sirolimus after liver transplantation for hepatocellular carcinoma beyond the Milan criteria., PMID:38763768
Binucleated human hepatocytes arise through late cytokinetic regression during endomitosis M phase., PMID:38727809
High expression of ACTL6A leads to poor prognosis of oral squamous cell carcinoma patients through promoting malignant progression., PMID:38523407
p53/E2F7 axis promotes temozolomide chemoresistance in glioblastoma multiforme., PMID:38454344
Copper nanoparticles and silver nanoparticles impair lymphangiogenesis in zebrafish., PMID:38273312
Transcription factor E2F7 activates PKMYT1 to partially suppress adriamycin sensitivity in gastric cancer through the MAPK signaling pathway., PMID:38253021
E2F7 serves as a potential prognostic biomarker for lung adenocarcinoma., PMID:38241554
CircPOFUT1 fosters colorectal cancer metastasis and chemoresistance via decoying miR-653-5p/E2F7/WDR66 axis and stabilizing BMI1., PMID:38230259
Transcription Factor E2F7 Hampers the Killing Effect of NK Cells against Colorectal Cancer Cells via Activating RAD18 Transcription., PMID:38073330
E2F7/RAD51AP1 Axis Inhibits Endometrial Cancer Sensitivity to 5-FU via the Fatty Acid Metabolic Pathway., PMID:37909953
Attenuation of binuclear hepatocytes in the paracancerous liver tissue is associated with short-term recurrence of hepatocellular carcinoma post-radical surgery., PMID:37882195
YAP silencing by RB1 mutation is essential for small-cell lung cancer metastasis., PMID:37739954
CISD2 transcriptional activated by transcription factor E2F7 promotes the malignant progression of cervical cancer., PMID:37615745
E2F family play important roles in tumorigenesis., PMID:37503582
Natural compound So-2 suppresses triple-negative breast cancer through inducing ferroptosis via downregulating transcription factor E2F7., PMID:37481196
E2F7 drives autotaxin/Enpp2 transcription via chromosome looping: Repression by p53 in murine but not in human carcinomas., PMID:37358838
Circ_0010235 confers cisplatin resistance in lung cancer by upregulating E2F7 through absorbing miR-379-5p., PMID:37277864
Abnormal expression pattern of lncRNA H19 participates in multiple myeloma bone disease by unbalancing osteogenesis and osteolysis., PMID:37058751
VIRMA promotes nasopharyngeal carcinoma, tumorigenesis, and metastasis by upregulation of E2F7 in an m6A-dependent manner., PMID:37028765
Molecular characteristics and transcriptional regulatory of spermatogenesis-related gene RFX2 in adult Banna mini-pig inbred line (BMI)., PMID:36922987
Harnessing transcriptionally driven chromosomal instability adaptation to target therapy-refractory lethal prostate cancer., PMID:36787737
Adding pieces to the puzzle of differentiated-to-anaplastic thyroid cancer evolution: the oncogene E2F7., PMID:36765037
Dexmedetomidine promotes ferroptotic cell death in gastric cancer via hsa_circ_0008035/miR-302a/E2F7 axis., PMID:36718915
Hsa-miR-195-5p Inhibits Autophagy and Gemcitabine Resistance of Lung Adenocarcinoma Cells via E2F7/CEP55., PMID:36658310
CRISPR screens reveal genetic determinants of PARP inhibitor sensitivity and resistance in prostate cancer., PMID:36650183
Circular RNA hsa_circ_0000519 contributes to angiogenesis and tumor progression in hepatocellular carcinoma through the miR-1296/E2F7 axis., PMID:36627545
Increasing Mononuclear Diploid Cardiomyocytes by Loss of E2F Transcription Factor 7/8 Fails to Improve Cardiac Regeneration After Infarct., PMID:36622904
lncRNA ENST00000585827 Contributes to the Progression of Endometrial Carcinoma via Regulating miR-424/E2F6/E2F7 Axis., PMID:36525235
For research use only. Not for human or drug use.
