Catalog No.
YHN28301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln108-Ala203
Predicted molecular weight
23.10 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8IVF2
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Protein AHNAK2, KIAA2019, C14orf78, AHNAK2
AHNAK2 confers 5-fluorouracil resistance in colorectal cancer via activation of the AKT/GSK-3β signaling axis., PMID:40382757
Omics data integration analysis identified new biological insights into chronic antibody-mediated rejection (CAMR)., PMID:39979925
AHNAK2: a potential diagnostic biomarker for pancreatic cancer related to cellular motility., PMID:39849106
The Immunomodulatory Effects of Vitamin D on COVID-19 Induced Glioblastoma Recurrence via the PI3K-AKT Signaling Pathway., PMID:39684661
Breast cancer genomic analyses reveal genes, mutations, and signaling networks., PMID:39496981
Breast cancer in adolescents and young adults has a specific biology and poor patient outcome compared with older patients., PMID:39405895
Impaired TGF-β signaling via AHNAK family mutations elicits an esophageal cancer subtype with sensitivities to genotoxic therapy and immunotherapy., PMID:39235488
Gene Expression Profiles of AHNAK2, DCSTAMP, FN1, and TERT Correlate With Mutational Status and Recurrence in Papillary Thyroid Carcinoma., PMID:39193983
Mutational and transcriptional profile predicts the prognosis of stage IV gastric cancer - Prognostic factors for metastatic gastric cancer., PMID:39043541
KLF7 promotes neuroblastoma differentiation through the GTPase signaling pathway by upregulating neuroblast differentiation-associated protein AHNAKs and glycerophosphodiesterase GDPD5., PMID:38924469
AHNAK2 Regulates NF-κB/MMP-9 Signaling to Promote Pancreatic Cancer Progression., PMID:38864962
AHNAK2 Promotes the Progression of Pancreatic Ductal Adenocarcinoma by Maintaining the Stability of c-MET., PMID:38751848
PRMT5-mediated arginine methylation of FXR1 is essential for RNA binding in cancer cells., PMID:38709899
Comprehensive somatic mutational analysis in glioblastoma: Implications for precision medicine approaches., PMID:38166029
Comparative study on genomic and epigenomic profiles of retinoblastoma or tuberous sclerosis complex via nanopore sequencing and a joint screening framework., PMID:38146007
Abnormal adipogenic signaling in the bone marrow mesenchymal stem cells contributes to supportive microenvironment for leukemia development., PMID:37817179
Insight of novel biomarkers for papillary thyroid carcinoma through multiomics., PMID:37795451
The mutational landscape of a US Midwestern breast cancer cohort reveals subtype-specific cancer drivers and prognostic markers., PMID:37454130
Downregulation of AHNAK2 inhibits cell cycle of lung adenocarcinoma cells by interacting with RUVBL1., PMID:37349884
A neural network model to screen feature genes for pancreatic cancer., PMID:37170188
Identification of Genetic Alterations in Rapid Progressive Glioblastoma by Use of Whole Exome Sequencing., PMID:36980325
AHNAK2 Urinary Protein Expression as Potential Biomarker for Bladder Cancer Detection: A Pilot Study., PMID:36416332
AHNAK2 Promotes the Progression of Differentiated Thyroid Cancer through PI3K/AKT Signaling Pathway., PMID:36089788
AHNAK2 is a biomarker and a potential therapeutic target of adenocarcinomas., PMID:36017889
Inhibition of AHNAK nucleoprotein 2 alleviates pulmonary fibrosis by downregulating the TGF-β1/Smad3 signaling pathway., PMID:35882062
Calcium sparks enhance the tissue fluidity within epithelial layers and promote apical extrusion of transformed cells., PMID:35830802
Exome sequencing in a child with neurodevelopmental disorder and epilepsy: Variant analysis of the AHNAK2 gene., PMID:35789128
Single-cell sequencing reveals CD133+CD44--originating evolution and novel stemness related variants in human colorectal cancer., PMID:35785618
The Obscure Potential of AHNAK2., PMID:35158796
AHNAK2 promotes thyroid carcinoma progression by activating the NF-κB pathway., PMID:34627772
Multiomics Differences in Lung Squamous Cell Carcinoma Patients with High Radiosensitivity Index Compared with Those with Low Radiosensitivity Index., PMID:34504628
Silencing of AHNAK2 restricts thyroid carcinoma progression by inhibiting the Wnt/β-catenin pathway., PMID:34374294
Common and mutation specific phenotypes of KRAS and BRAF mutations in colorectal cancer cells revealed by integrative -omics analysis., PMID:34233735
Effective treatment of a BRAF V600E-mutant epithelioid glioblastoma patient by vemurafenib: a case report., PMID:34232949
Application of Label-Free Proteomics for Quantitative Analysis of Urothelial Carcinoma and Cystitis Tissue., PMID:33950498
Multiomics Analysis of Transcriptome, Epigenome, and Genome Uncovers Putative Mechanisms for Dilated Cardiomyopathy., PMID:33860048
Multiomics Analysis of Genetics and Epigenetics Reveals Pathogenesis and Therapeutic Targets for Atrial Fibrillation., PMID:33834070
Identification of PIK3CA multigene mutation patterns associated with superior prognosis in stomach cancer., PMID:33827485
AHNAK2 Promotes Migration, Invasion, and Epithelial-Mesenchymal Transition in Lung Adenocarcinoma Cells via the TGF-β/Smad3 Pathway., PMID:33363388
AHNAK2 is a novel prognostic marker and correlates with immune infiltration in papillary thyroid cancer: Evidence from integrated analysis., PMID:33218938
Correlation between prognostic indicator AHNAK2 and immune infiltrates in lung adenocarcinoma., PMID:33168407
Down-Regulation of AHNAK2 Inhibits Cell Proliferation, Migration and Invasion Through Inactivating the MAPK Pathway in Lung Adenocarcinoma., PMID:33000678
AHNAK2 Is Associated with Poor Prognosis and Cell Migration in Lung Adenocarcinoma., PMID:32904605
An Integrated Microarray Analysis Reveals Significant Diagnostic and Prognostic Biomarkers in Pancreatic Cancer., PMID:32235821
PDAC-ANN: an artificial neural network to predict pancreatic ductal adenocarcinoma based on gene expression., PMID:32005189
Methylation of drug resistance-related genes in chemotherapy-sensitive Epstein-Barr virus-associated gastric cancer., PMID:31736281
AHNAK Nucleoprotein 2 Performs a Promoting Role in the Proliferation and Migration of Uveal Melanoma Cells., PMID:31621397
CXCL16 positively correlated with M2-macrophage infiltration, enhanced angiogenesis, and poor prognosis in thyroid cancer., PMID:31527616
Linkage analysis and whole exome sequencing reveals AHNAK2 as a novel genetic cause for autosomal recessive CMT in a Malaysian family., PMID:31011849
Integrated Fourier Transform Infrared Imaging and Proteomics for Identification of a Candidate Histochemical Biomarker in Bladder Cancer., PMID:30770125
For research use only. Not for human or drug use.
