Catalog No.
YHH38401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met100-Leu385
Predicted molecular weight
33.74 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q16829
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PYST2, Dual specificity protein phosphatase PYST2, Dual specificity protein phosphatase 7, DUSP7
Genomic analysis reveals molecular characterization of CD30+ and CD30- extranodal natural killer/T-cell lymphomas (ENKTLs)., PMID:39187207
Let-7c-5p Down Regulates the Proliferation of Colorectal Cancer Through the MAPK-ERK-Signaling Pathway., PMID:38095736
Loss of SETD2 aggravates colorectal cancer progression caused by SMAD4 deletion through the RAS/ERK signalling pathway., PMID:37962020
Identification of DUSP7 as an RNA Marker for Prognostic Stratification in Acute Myeloid Leukemia: Evidence from Large Population Cohorts., PMID:37538139
Expression of dual-specificity phosphatases in TGFß1-induced EMT in SKOV3 cells., PMID:37476896
Whole transcriptome sequencing analysis of blood plasma-derived exosomes from immune-related hearing loss., PMID:37244117
Differential cell-cycle control by oscillatory versus sustained Hes1 expression via p21., PMID:37200191
Variances in the Expression Profile of DUSP1-7 and miRNAs Regulating their Expression in the HaCat Line under LPS and Cyclosporine A., PMID:37032503
Dual-specificity phosphatases 22-deficient T cells contribute to the pathogenesis of ankylosing spondylitis., PMID:36765305
Dual specificity phosphatase 7 drives the formation of cardiac mesoderm in mouse embryonic stem cells., PMID:36227898
Dual Specific Phosphatase 7 Exacerbates Dilated Cardiomyopathy, Heart Failure, and Cardiac Death by Inactivating the ERK1/2 Signaling Pathway., PMID:35596107
DUSP7: an Unusual Player in Adverse Cardiac Remodeling., PMID:35588349
Transcription Factor FOSL1 Enhances Drug Resistance of Breast Cancer through DUSP7-Mediated Dephosphorylation of PEA15., PMID:34907034
DUSP7 inhibits cervical cancer progression by inactivating the RAS pathway., PMID:34435746
DUSP7 regulates the activity of ERK2 to promote proper chromosome alignment during cell division., PMID:33865857
Deubiquitinase USP7 regulates Drosophila aging through ubiquitination and autophagy., PMID:33221768
Targeting DUSP7 signaling alleviates hepatic steatosis, inflammation and oxidative stress in high fat diet (HFD)-fed mice via suppression of TAK1., PMID:32311490
Circ-ABCB10 Contributes to Paclitaxel Resistance in Breast Cancer Through Let-7a-5p/DUSP7 Axis., PMID:32273769
Transcriptional analysis of THP-1 cells infected with Leishmania infantum indicates no activation of the inflammasome platform., PMID:31961876
MAP4K Family Kinases and DUSP Family Phosphatases in T-Cell Signaling and Systemic Lupus Erythematosus., PMID:31766293
Regulation of Dual-Specificity Phosphatase (DUSP) Ubiquitination and Protein Stability., PMID:31151270
Asporin promotes cell proliferation via interacting with PSMD2 in gastric cancer., PMID:31136974
The E2F1-miR-520/372/373-SPOP Axis Modulates Progression of Renal Carcinoma., PMID:30348808
Linc-RoR promotes MAPK/ERK signaling and confers estrogen-independent growth of breast cancer., PMID:29041978
Expression Profiling of the MAP Kinase Phosphatase Family Reveals a Role for DUSP1 in the Glioblastoma Stem Cell Niche., PMID:28822081
l-Homocysteine-induced cathepsin V mediates the vascular endothelial inflammation in hyperhomocysteinaemia., PMID:28631302
mRNA profiling identifies low levels of phosphatases dual‐specific phosphatase‐7 (DUSP7) and cell division cycle‐25B (CDC25B) in patients with early arthritis., PMID:28253537
MiR-107 induces TNF-α secretion in endothelial cells causing tubular cell injury in patients with septic acute kidney injury., PMID:28063928
The Phosphatase Dusp7 Drives Meiotic Resumption and Chromosome Alignment in Mouse Oocytes., PMID:27783954
Ras and TGF-β signaling enhance cancer progression by promoting the ΔNp63 transcriptional program., PMID:27555661
Differential expression profiles and roles of inducible DUSPs and ERK1/2-specific constitutive DUSP6 and DUSP7 in microglia., PMID:26435497
Celecoxib can suppress expression of genes associated with PGE2 pathway in chondrocytes under inflammatory conditions., PMID:26379884
Phosphotyrosine Substrate Sequence Motifs for Dual Specificity Phosphatases., PMID:26302245
Live imaging RNAi screen reveals genes essential for meiosis in mammalian oocytes., PMID:26147080
Structure of human dual-specificity phosphatase 7, a potential cancer drug target., PMID:26057789
ARF triggers senescence in Brca2-deficient cells by altering the spectrum of p53 transcriptional targets., PMID:24162189
MYC/MAX control ERK signaling and pluripotency by regulation of dual-specificity phosphatases 2 and 7., PMID:23592794
MAP kinase genes and colon and rectal cancer., PMID:23027623
Caspase-3 cleavage of DUSP6/MKP3 at the interdomain region generates active MKP3 fragments that regulate ERK1/2 subcellular localization and function., PMID:22504224
Phosphorylation of the kinase interaction motif in mitogen-activated protein (MAP) kinase phosphatase-4 mediates cross-talk between protein kinase A and MAP kinase signaling pathways., PMID:21908610
Genome-wide gain-of-function screen identifies novel regulators of pluripotency., PMID:20629179
Dual-specificity MAP kinase phosphatases (MKPs) and cancer., PMID:18330678
Expression of ERK signaling inhibitors Dusp6, Dusp7, and Dusp9 during mouse ear development., PMID:18058922
The Pyst2-L phosphatase is involved in cell-crowding., PMID:16386315
Effects of solutes on solubilization and refolding of proteins from inclusion bodies with high hydrostatic pressure., PMID:16385003
Does the dual-specificity MAPK phosphatase Pyst2-L lead a monogamous relationship with the Erk2 protein?, PMID:15081539
cDNA microarray analysis reveals an overexpression of the dual-specificity MAPK phosphatase PYST2 in acute leukemia., PMID:14674243
Characterization of the dual-specificity phosphatase PYST2 and its transcripts., PMID:14603440
Dual-specificity phosphatase Pyst2-L is constitutively highly expressed in myeloid leukemia and other malignant cells., PMID:14576828
Regulation of MAP kinase signaling modules by scaffold proteins in mammals., PMID:14570565
For research use only. Not for human or drug use.
