Catalog No.
YHD66202
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp2-Ser41
Predicted molecular weight
16.82 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P25106
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CXCR-7, RDC1, C-X-C chemokine receptor type 7, RDC-1, Chemokine orphan receptor 1, G-protein coupled receptor 159, Atypical chemokine receptor 3, CMKOR1, CXCR7, GPR159, G-protein coupled receptor RDC1 homolog, ACKR3, CXC-R7
The Critical Role and Therapeutic Potential of the CXCR Family in Skin Diseases., PMID:40464497
The Effect of Tff3 Deficiency on the Liver of Mice Exposed to a High-Fat Diet., PMID:40426854
Triazole-quinoxaline attenuates epithelial-to-mesenchymal transition by suppressing the Wnt/β-catenin pathway in human colorectal cancer cells., PMID:40414329
Highly Specific Cytokine Receptor-Targeting Chimeras for Targeted Membrane Protein Degradation and Sensitization of Osimertinib in EGFR-Mutated Non-Small-Cell Lung Cancer., PMID:40401615
Cellular communication networks in fibrosis: Insights from the MASLD pig model., PMID:40304567
Activation of CXCR7 exerts an inhibitory effect on adipogenesis through regulation of β-arrestin2/Wnt and AKT signalling., PMID:40302245
CXCR7 promoted proliferation, migration and invasion in HCC Cells by inactivating Hippo-YAP signaling., PMID:40249447
Distinct activation mechanisms of CXCR4 and ACKR3 revealed by single-molecule analysis of their conformational landscapes., PMID:40232828
Structural visualization of small molecule recognition by CXCR3 uncovers dual-agonism in the CXCR3-CXCR7 system., PMID:40155369
A patent review of CXCR7 modulators (2019-present)., PMID:40122070
Targeting the CXCR7 pathway with TC14012 to inhibit endothelial necroptosis and lung cancer metastasis., PMID:40049294
Modulation of biomaterial-induced foreign body response by regulating the differentiation and migration of Treg cells through the CXCL12-CXCR4/7 axis., PMID:39932368
Distinctive Macrophage Migration Inhibitory Factor Receptor Patterns and Soluble Biomarkers in Rheumatoid Arthritis: Unveiling Key Associations with Disease Activity., PMID:39914814
Stromal Cell Derived Factor-1 Promotes Hepatic Insulin Resistance via Inhibiting Hepatocyte Lipophagy., PMID:39855896
Regulation of the chemokine receptors CXCR4 and ACKR3 by receptor activity-modifying proteins., PMID:39662834
The causative effect of CXCR7 on experimental autoimmune prostatitis injury and fibrosis., PMID:39608177
Chemokine signaling in tumors: potential role of CXC chemokines and their receptors as glioblastoma therapeutic targets., PMID:39582130
Exosomes derived from M2 macrophages promote fibroblast autophagy to contribute to hypertrophic scar formation via CXCL2/CXCR7/mTOR pathway., PMID:39557042
Chemokine receptor CXCR7 antagonism ameliorates cardiac and renal fibrosis induced by mineralocorticoid excess., PMID:39505939
ACKR3 in Skin Homeostasis, an Overlooked Player in the CXCR4/CXCL12 Axis., PMID:39466217
Hemin-induced platelet activation is regulated by the ACKR3 chemokine surface receptor and has implications for passivation of vulnerable atherosclerotic plaques., PMID:39387619
ACKR3 agonism induces heterodimerization with chemokine receptor CXCR4 and attenuates platelet function., PMID:39373210
AI-assisted models to predict chemotherapy drugs modified with C60 fullerene derivatives., PMID:39319207
Heterogeneous expression of the atypical chemokine receptor ACKR3 in glioblastoma patient-derived tissue samples and cell cultures., PMID:39300240
CXCR7 genetic variant predicts treatment response of pegylated-interferon α in HBeAg-positive chronic hepatitis B patients., PMID:39265656
Role of chemokine receptors in gastrointestinal mucosa., PMID:39260937
Deficient GATA6-CXCR7 signaling leads to bicuspid aortic valve., PMID:39253784
The SDF-1/CXCR4 axis is involved in adipose-derived stem cell migration., PMID:39149821
Novel Small-Molecule Atypical Chemokine Receptor 3 Agonists: Design, Synthesis, and Pharmacological Evaluation for Antiplatelet Therapy., PMID:39116445
Investigational CXCR4 inhibitors in early phase development for the treatment of hematological malignancies., PMID:39096094
Disulfide bond replacement with non-reducible side chain to tail macrolactamization for the development of potent and selective CXCR4 peptide antagonists endowed with flanking binding sites., PMID:39053189
Macrophage Migration Inhibitory Factor (MIF) Upregulates CXCR7 and Contributes to Chemotherapy Resistance in Colorectal Cancer., PMID:39018005
The effect of itraconazole, a strong CYP3A4 inhibitor, on the pharmacokinetics of the first-in-class ACKR3/CXCR7 antagonist, ACT-1004-1239., PMID:39010703
Conformational dynamics underlying atypical chemokine receptor 3 activation., PMID:39008676
CD74 is a functional MIF receptor on activated CD4+ T cells., PMID:38992165
Crosstalk between CXCL12/CXCR4/ACKR3 and the STAT3 Pathway., PMID:38920657
CXCR7 activation evokes the anti-PD-L1 antibody against glioblastoma by remodeling CXCL12-mediated immunity., PMID:38898023
ACKR3 Antagonism Enhances the Repair of Demyelinated Lesions Through Both Immunomodulatory and Remyelinating Effects., PMID:38819698
Structural basis for selectivity and antagonism in extracellular GPCR-nanobodies., PMID:38816420
Protective Effect of CXCR7 Against Hypoxia/Reoxygenation Injury in Renal Tubular Epithelial Cells., PMID:38806964
Evaluating CXCL12 for Effects on Reactive Gene Expression in Primary Astrocytes., PMID:38802573
Bilayer lipids modulate ligand binding to atypical chemokine receptor 3., PMID:38776922
CXCR7 promotes pulmonary vascular remodeling via targeting p38/MMP2 pathway in pulmonary arterial hypertension., PMID:38738224
Synthesis, Antiproliferative Activity and Molecular Docking Analysis of Both Enantiomerically Pure Decursin Derivatives as Anticancer Agents., PMID:38735699
Multiplex Detection of Fluorescent Chemokine Binding to CXC Chemokine Receptors by NanoBRET., PMID:38732237
Relationship between chemokine/chemokine receptor and glioma prognosis and outcomes: Systematic review and meta-analysis., PMID:38631221
Pleiotropic Role of Rainbow Trout CXCRs in Response to Disease and Environment: Insights from Transcriptional Signatures and Structure Analysis., PMID:38540757
The Role of CXCL11 and its Receptors in Cancer: Prospective but Challenging Clinical Targets., PMID:38533911
G protein subunit alpha i2's pivotal role in angiogenesis., PMID:38505600
ACKR3 in olfactory glia cells shapes the immune defense of the olfactory mucosa., PMID:38477581
For research use only. Not for human or drug use.
