Catalog No.
YHB99202
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr108-Gln491
Predicted molecular weight
46.49 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P02675
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
FGB, Fibrinogen beta chain
The intratumoral microbiota heterogenicity is related to the prognosis and tumorigenesis of cervical cancer., PMID:40433663
-455A Allele May Be a Protective Locus for Aseptic Lower Extremity Superficial Thrombophlebitis., PMID:40397612
Human-Derived Proteome Characterization of Tongue Coating in Colorectal Cancer., PMID:40378345
The Platelet Activation Signaling Pathway Regulated by Fibrinogen and Homo-Gamma-Linolenic Acid (C20:3)-Associated Lipid Metabolism Is Involved in the Maintenance of Early Pregnancy in Chinese Native Yellow Cattle., PMID:40362034
Chronic sleep curtailment expediates brain aging by activating the complement and coagulation cascades in mice., PMID:40027811
Predicting the hub interactome of COVID-19 and oral squamous cell carcinoma: uncovering ALDH-mediated Wnt/β-catenin pathway activation via salivary inflammatory proteins., PMID:39901050
Fibrinogen genotypes and their impact on recurrence of venous thromboembolism and family history: A prospective population-based study., PMID:39828282
The β-Chain Mutation p.Arg17Stop Impairs Fibrinogen Synthesis and Secretion: A Nonsense Mutation Associated With Hypofibrinogenemia., PMID:39665495
SARS-COV-2 ORF9b Dysregulate Fibrinogen and Albumin Genes in a Liver Cell Line., PMID:39582820
Label-based comparative proteomics of oral mucosal tissue to understand progression of precancerous lesions to oral squamous cell carcinoma., PMID:39483176
Identification of FGG as a Biomarker in Early Gastric Cancer via Tissue Proteomics and Clinical Verification., PMID:39417528
Proteomic analysis and experimental validation reveal the blood-brain barrier protective of Huanshaodan in the treatment of SAMP8 mouse model of Alzheimer's disease., PMID:39369234
Association between genetic polymorphisms in fibrinogen genes and bleeding risk in patients treated with direct oral anticoagulants., PMID:38904499
Exosomes Secreted by Wharton's Jelly-Derived Mesenchymal Stem Cells Promote the Ability of Cell Proliferation and Migration for Keratinocyte., PMID:38731977
Network pharmacology analysis and experimental verification of the antithrombotic active compounds of trichosanthis pericarpium (Gualoupi) in treating coronary heart disease., PMID:38614263
Filamentous fungus-produced human monoclonal antibody provides protection against SARS-CoV-2 in hamster and non-human primate models., PMID:38485931
Multi-Omics Approaches for Liver Reveal the Thromboprophylaxis Mechanism of Aspirin Eugenol Ester in Rat Thrombosis Model., PMID:38396823
Distinct mechanisms underlying the therapeutic effects of low-molecular-weight heparin and chondroitin sulfate on Parkinson's disease., PMID:38296150
Vitamin D3 improved hypoxia-induced lung injury by inhibiting the complement and coagulation cascade and autophagy pathway., PMID:38166725
Biomarkers for predicting the severity of spinal cord injury by proteomic analysis., PMID:38155913
Fibrinogen B β promoter polymorphism may not be associated with pulmonary embolism., PMID:37978815
Effect of Supplementation with Curcuma longa and Rosmarinus officinalis Extract Mixture on Acute Phase Protein, Cathelicidin, Defensin and Cytolytic Protein Gene Expression in the Livers of Young Castrated Polish White Improved Bucks., PMID:37895281
Plasma metabolomics and proteomics reveal novel molecular insights and biomarker panel for cholelithiasis., PMID:37866078
Erythroid-transdifferentiated myeloid cells promote portal vein tumor thrombus in hepatocellular carcinoma., PMID:37649603
Pistacia vera Extract Potentiates the Effect of Melatonin on Human Melatonin MT1 and MT2 Receptors with Functional Selectivity., PMID:37514032
A multi-mineral intervention to counter pro-inflammatory activity and to improve the barrier in human colon organoids., PMID:37476158
Identification of Plasma Proteomic Biomarkers in Patients with Mild Cognitive Impairment., PMID:36684491
Fibrinogen beta chain may be a potential predict biomarker for pre-eclampsia: A preliminary study., PMID:36566955
Proteomic analysis of small extracellular vesicles from the plasma of patients with hepatocellular carcinoma., PMID:36471393
Effects of berberine hydrochloride on immune response in the crab Charybdis japonica., PMID:35953779
Jiedutongluotiaogan formula restores pancreatic function by suppressing excessive autophagy and endoplasmic reticulum stress., PMID:35944284
Brain proteome profiling implicates the complement and coagulation cascade in multiple system atrophy brain pathology., PMID:35657417
Efficacy and Mechanism of Buyang Huanwu Decoction in Patients With Ischemic Heart Failure: A Randomized, Double-Blind, Placebo-Controlled Trial Combined With Proteomic Analysis., PMID:35370712
Altered fibrinogen level and fibrin clot structure in myostatin homozygous mutant pig., PMID:35285059
Fibrinogen β chain and FXIII polymorphisms affect fibrin clot properties in acute pulmonary embolism., PMID:34783023
The Correlation Between FGB Promoter Polymorphism and Clotting Function in Patients With Idiopathic Lower Extremity Deep Venous Thrombosis., PMID:34583575
Multiple sclerosis and genetic polymorphisms in fibrinogen-mediated hemostatic pathways: a case-control study., PMID:34561786
Potential biomarkers: differentially expressed proteins of the extrinsic coagulation pathway in plasma samples from patients with depression., PMID:34488523
An FGA Frameshift Variant Associated with Afibrinogenemia in Dachshunds., PMID:34356081
Accelerated accumulation of fibrinogen peptide chains with Aβ deposition in Alzheimer's disease (AD) mice and human AD brains., PMID:34197775
Predictive value of C-reactive protein for radiographic spinal progression in axial spondyloarthritis in dependence on genetic determinants of fibrin clot formation and fibrinolysis., PMID:34187873
The β-chain mutation p.Trp433Stop impairs fibrinogen secretion: A novel nonsense mutation associated with hypofibrinogenemia., PMID:34185392
An association between fibrinogen gene polymorphisms and diabetic peripheral neuropathy in young patients with type 1 diabetes., PMID:34061326
Fibrinogen Dysregulation is a Prominent Process in Fatal Conditions of COVID-19 Infection; a Proteomic Analysis., PMID:34027421
iTRAQ-based quantitative proteomics and network pharmacology revealing hemostatic mechanism mediated by Zingiberis Rhizome Carbonisata in deficiency-cold and Hemorrhagic Syndrome rat models., PMID:33831383
Exosomes from COVID-19 Patients Carry Tenascin-C and Fibrinogen-β in Triggering Inflammatory Signals in Cells of Distant Organ., PMID:33804769
Quantile-dependent expressivity of serum C-reactive protein concentrations in family sets., PMID:33628645
A Novel Nonsense Mutation in FGB (c.1421G>A; p.Trp474Ter) in the Beta Chain of Fibrinogen Causing Hypofibrinogenemia with Bleeding Phenotype., PMID:33322159
Differential proteomics mass spectrometry of melanosis coli., PMID:32774690
Genetic Variants in the FGB and FGG Genes Mapping in the Beta and Gamma Nodules of the Fibrinogen Molecule in Congenital Quantitative Fibrinogen Disorders Associated with a Thrombotic Phenotype., PMID:32610551
For research use only. Not for human or drug use.
