Catalog No.
YHB10101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp57-Arg190
Predicted molecular weight
17.23 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O75143
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ATG13, KIAA0652, Autophagy-related protein 13
Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex., PMID:40442316
TRIM22 functions as a scaffold protein for autophagy initiation., PMID:40337095
Hyperoside suppresses NSCLC progression by inducing ATG13-mediated autophagy and apoptosis., PMID:40250077
Mycobacterium tuberculosis phagosome Ca2+ leakage triggers multimembrane ATG8/LC3 lipidation to restrict damage in human macrophages., PMID:40138395
TGFB signaling induces mitophagy via PLSCR3-mediated cardiolipin externalization in conjunction with a BNIP3L/NIX-, BNIP3-, and FUNDC1-dependent mechanism., PMID:40119553
Pyruvate dehydrogenase alleviates macrophage autophagy in Hcy-induced ApoE -/- mice., PMID:39980347
Stress granules as transient reservoirs for autophagy proteins: a key mechanism for plant recovery from heat stress., PMID:39973093
Potential ER tubular lumen sensing by intrinsically disordered regions., PMID:39925135
Mec1-mediated Atg9 phosphorylation regulates the PAS recruitment of Atg9 vesicles upon energy stress., PMID:39913206
High Glucose-Induced Senescent Fibroblasts-Derived Exosomal miR-497 Inhibits Wound Healing by Regulating Endothelial Cellular Autophagy via ATG13., PMID:39831298
Inactivation of ATG13 stimulates chronic demyelinating pathologies in muscle-serving nerves and spinal cord., PMID:39777574
Stress granules sequester autophagy proteins to facilitate plant recovery from heat stress., PMID:39738069
Ferrostatin supplementation improves microalgal activities and nutrient removal in wastewater under high temperature shock: From ferroptosis-like inhibition to enhanced oxidation resistance., PMID:39721506
Lysosomal damage due to cholesterol accumulation triggers immunogenic cell death., PMID:39663580
MEHP induced mitochondrial damage by promoting ROS production in CIK cells, leading to apoptosis, autophagy, cell cycle arrest., PMID:39586385
MiR-192 and miR-731 synergically inhibit RGNNV infection by targeting ULK1-mediated autophagy in sea perch (Lateolabrax japonicus)., PMID:39437957
The autophagy initiation factor ATG13 mRNA is stabilized by the RNA-binding protein YBX3., PMID:39414370
The ULK1 effector BAG2 regulates autophagy initiation by modulating AMBRA1 localization., PMID:39207901
Palmitoylation of ULK1 by ZDHHC13 plays a crucial role in autophagy., PMID:39169022
The emerging significance of Vac8, a multi-purpose armadillo-repeat protein in yeast., PMID:39045779
TAX1BP1 and FIP200 orchestrate non-canonical autophagy of p62 aggregates for mouse neural stem cell maintenance., PMID:39021082
Comprehensive analysis of non-selective and selective autophagy in yeast atg mutants and characterization of autophagic activity in the absence of the Atg8 conjugation system., PMID:38843068
FoxO1 silencing in Atp7b-/- neural stem cells attenuates high copper-induced apoptosis via regulation of autophagy., PMID:38837406
MCT1-mediated transport of valeric acid promotes porcine preimplantation embryo development by improving mitochondrial function and inhibiting the autophagic AMPK-ULK1 pathway., PMID:38805997
Galectin-3 and Autophagy in Renal Acute Tubular Necrosis., PMID:38612416
Abemaciclib and Vacuolin-1 decrease aggregate-prone TDP-43 accumulation by accelerating autophagic flux., PMID:38596406
LC3B conjugation machinery promotes autophagy-independent HIV-1 entry in CD4+ T lymphocytes., PMID:38566318
GZ17-6.02 interacts with proteasome inhibitors to kill multiple myeloma cells., PMID:38441437
GZ17-6.02 interacts with bexarotene to kill mycosis fungoides cells., PMID:38329728
Sodium fluoride-induced autophagy of ameloblast-like cells via the p-ULk1/ATG13/LC3B pathway in vitro., PMID:38321366
A metabolite sensor subunit of the Atg1/ULK complex regulates selective autophagy., PMID:38316984
Novel exosomal circEGFR facilitates triple negative breast cancer autophagy via promoting TFEB nuclear trafficking and modulating miR-224-5p/ATG13/ULK1 feedback loop., PMID:38280941
THADA inhibits autophagy and increases 5-FU sensitivity in gastric cancer cells via the PI3K/AKT/mTOR signaling pathway., PMID:38234670
Decoding the function of Atg13 phosphorylation reveals a role of Atg11 in bulk autophagy initiation., PMID:38233718
Mitophagy Decreases in the Peripheral Vestibular System of Aged C57BL/6J Mice., PMID:38148055
Mec1-Rad53 Signaling Regulates DNA Damage-Induced Autophagy and Pathogenicity in Candida albicans., PMID:38132782
ULK1 seen at the single-molecule level during autophagy initiation., PMID:37992308
Distinct roles of core autophagy-related genes in zebrafish definitive hematopoiesis., PMID:37921505
LILAR, a novel long noncoding RNA regulating autophagy in the liver tissues of endotoxemic mice through a competing endogenous RNA mechanism., PMID:37829506
Lysosome damage triggers direct ATG8 conjugation and ATG2 engagement via non-canonical autophagy., PMID:37796195
ULK1 forms distinct oligomeric states and nanoscopic structures during autophagy initiation., PMID:37774021
Iditarod, a Drosophila homolog of the Irisin precursor FNDC5, is critical for exercise performance and cardiac autophagy., PMID:37722048
Autophagy and LC3-associated phagocytosis contribute negatively to the killing capability of THP-1-derived macrophages against Candida albicans at the mid-stage., PMID:37717912
Integrative analysis of the prognostic value and immune microenvironment of mitophagy-related signature for multiple myeloma., PMID:37700273
Exosomal circHIPK3 derived from umbilical cord-derived mesenchymal stem cells enhances skin fibroblast autophagy by blocking miR-20b-5p/ULK1/Atg13 axis., PMID:37688345
TOR-mediated Ypt1 phosphorylation regulates autophagy initiation complex assembly., PMID:37635626
A new regulator of autophagy initiation in glia., PMID:37615623
The role of the HORMA domain proteins ATG13 and ATG101 in initiating autophagosome biogenesis., PMID:37567770
Tracking the transition from an ATG9A vesicle to an autophagosome., PMID:37405380
Metamorphosis by ATG13 and ATG101 in human autophagy initiation., PMID:37394799
For research use only. Not for human or drug use.
