Catalog No.
YHA50601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys37-Ser208
Predicted molecular weight
22.19 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O15372
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
EIF3H, eIF-3-gamma, eIF3h, eIF3 p40 subunit, EIF3S3, Eukaryotic translation initiation factor 3 subunit 3, Eukaryotic translation initiation factor 3 subunit H
Overexpression of the eukaryotic translation initiation factor FveIF3h represses CER4/FAR3 translation and attenuates the synthesis of cuticular wax in strawberry leaves., PMID:40490179
Expression of PSMD14 in lung adenocarcinoma and its impact on immune cell infiltration and prognosis: a comprehensive analysis based on RNA and single-cell RNA sequencing., PMID:40475775
A piRNA chemosensitizes doxorubicin in tongue squamous cell carcinoma by targeting FDFT1 and inhibiting the EIF3H/HIF1α/CYPOR axis., PMID:40339976
Exploration of mRNA-modifying METTL3 oncogene as momentous prognostic biomarker responsible for colorectal cancer development., PMID:40177651
CGREF1 facilitates the cell proliferation, migration and invasion of hepatocellular carcinoma cells via regulation of EIF3H/ Wnt/β-Catenin signaling axis., PMID:40069645
N6-methyladenosine-mediated EIF3H promotes anaplastic thyroid cancer progression and ferroptosis resistance by stabilizing β-catenin., PMID:39984062
Pharmacological Dissection Identifies Retatrutide Overcomes the Therapeutic Barrier of Obese TNBC Treatments through Suppressing the Interplay between Glycosylation and Ubiquitylation of YAP., PMID:39868848
Deubiquitinating enzymes in breast cancer: in silico analysis of gene expression and metastatic correlation., PMID:39671715
Perturbations in eIF3 subunit stoichiometry alter expression of ribosomal proteins and key components of the MAPK signaling pathways., PMID:39495207
Proteomic Characterization of Corneal Epithelial and Stromal Cell-Derived Extracellular Vesicles., PMID:39408670
PCAF-mediated acetylation of METTL3 impairs mRNA translation efficiency in response to oxidative stress., PMID:39096338
The EIF3H-HAX1 axis increases RAF-MEK-ERK signaling activity to promote colorectal cancer progression., PMID:38514606
A genetic screen identifies C. elegans eif-3.H and hrpr-1 as pro-apoptotic genes and potential activators of egl-1 expression., PMID:38434221
Unveiling dysregulated lncRNAs and networks in non-syndromic cleft lip with or without cleft palate pathogenesis., PMID:38200098
Using meta-analysis and machine learning to investigate the transcriptional response of immune cells to Leishmania infection., PMID:38190401
The deubiquitinase EIF3H promotes hepatocellular carcinoma progression by stabilizing OGT and inhibiting ferroptosis., PMID:37559097
Repeat polymorphisms underlie top genetic risk loci for glaucoma and colorectal cancer., PMID:37527660
Suppressors of Break-Induced Replication in Human Cells., PMID:36833325
EIF3H stabilizes CCND1 to promotes intrahepatic cholangiocarcinoma progression via Wnt/β-catenin signaling., PMID:36350008
New roles of N6-methyladenosine methylation system regulating the occurrence of non-alcoholic fatty liver disease with N6-methyladenosine-modified MYC., PMID:36120320
Relationship of micro-RNA, mRNA and eIF Expression in Tamoxifen-Adapted MCF-7 Breast Cancer Cells: Impact of miR-1972 on Gene Expression, Proliferation and Migration., PMID:35883472
Knockdown of EIF3H inhibits the development and progression of pancreatic cancer by regulating cell proliferation and apoptosis in vitro., PMID:35809300
Exosomal circLPAR1 functions in colorectal cancer diagnosis and tumorigenesis through suppressing BRD4 via METTL3-eIF3h interaction., PMID:35164758
Celastrus orbiculatus Extract Reduces Stemness of Gastric Cancer Stem Cells by Targeting PDCD4 and EIF3H., PMID:34802261
Integrated Analysis of Weighted Gene Coexpression Network Analysis Identifying Six Genes as Novel Biomarkers for Alzheimer's Disease., PMID:34367470
Identification of Full-Length Wild-Type and Mutant Huntingtin Interacting Proteins by Crosslinking Immunoprecipitation in Mice Brain Cortex., PMID:34151850
The effect of miR-496 on eIF3h in lung invasive adenocarcinoma., PMID:34038061
Requirement of splicing factor hnRNP A2B1 for tumorigenesis of melanoma stem cells., PMID:33509274
EIF3H knockdown inhibits malignant melanoma through regulating cell proliferation, apoptosis and cell cycle., PMID:33508274
EIF3H promotes aggressiveness of esophageal squamous cell carcinoma by modulating Snail stability., PMID:32867821
The E3 ubiquitin ligase Itch deficiency promotes antigen-driven B-cell responses in mice., PMID:32652569
EIF3H Orchestrates Hippo Pathway-Mediated Oncogenesis via Catalytic Control of YAP Stability., PMID:32269044
Colorectal cancer genetic variants are also associated with serrated polyposis syndrome susceptibility., PMID:32170005
EIF3H interacts with PDCD4 enhancing lung adenocarcinoma cell metastasis., PMID:32064160
The Prognostic Significance of Eukaryotic Translation Initiation Factors (eIFs) in Endometrial Cancer., PMID:31817792
Integrated Analysis of the Gene Expression Changes During Colorectal Cancer Progression by Bioinformatic Methods., PMID:31246501
DISC1 promotes translation maintenance during sodium arsenite-induced oxidative stress., PMID:31075539
Translational Regulation of Plant Response to High Temperature by a Dual-Function tRNAHis Guanylyltransferase in Rice., PMID:31075443
mRNA circularization by METTL3-eIF3h enhances translation and promotes oncogenesis., PMID:30232453
Eukaryotic translation initiation factor EIF3H potentiates gastric carcinoma cell proliferation., PMID:30060823
A harmine-derived beta-carboline displays anti-cancer effects in vitro by targeting protein synthesis., PMID:28322844
Elevated expression of eukaryotic translation initiation factor 3H is associated with proliferation, invasion and tumorigenicity in human hepatocellular carcinoma., PMID:27340783
Effects of TMEM9 gene on cell progression in hepatocellular carcinoma by RNA interference., PMID:27220462
The Rice Eukaryotic Translation Initiation Factor 3 Subunit f (OseIF3f) Is Involved in Microgametogenesis., PMID:27200010
Prenatal diagnosis and array comparative genomic hybridization characterization of interstitial deletions of 8q23.3-q24.11 and 8q24.13 associated with Langer-Giedion syndrome, Cornelia de Lange syndrome and haploinsufficiency of TRPS1, RAD21 and EXT1., PMID:26522117
Biological insights into the expression of translation initiation factors from recombinant CHOK1SV cell lines and their relationship to enhanced productivity., PMID:26420881
The histone deacetylase inhibitor, Vorinostat, represses hypoxia inducible factor 1 alpha expression through translational inhibition., PMID:25166596
Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade., PMID:24927736
The S. pombe translation initiation factor eIF4G is Sumoylated and associates with the SUMO protease Ulp2., PMID:24818994
Translational control of Arabidopsis meristem stability and organogenesis by the eukaryotic translation factor eIF3h., PMID:24736281
For research use only. Not for human or drug use.
