Catalog No.
YHA25201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser586-Ser640
Predicted molecular weight
18.84 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O14639
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
KIAA0059, LIMAB1, ABLIM1, Actin-binding LIM protein family member 1, ABLIM, Actin-binding double zinc finger protein, Limatin, Actin-binding LIM protein 1, abLIM-1
Upregulation of ABLIM1 Differentiates Intrahepatic Cholangiocarcinoma from Hepatocellular Carcinoma and Both Colorectal and Pancreatic Adenocarcinoma Liver Metastases., PMID:39766812
Predictive biosignatures for hospitalization in patients with virologically confirmed COVID-19., PMID:39730204
Molecular mechanisms of GSK3β-driven modulation of ABLIM1 and titin interactions in cardiac muscle., PMID:39713372
Comparative Proteomic and Phosphoproteomic Analyses Reveal Molecular Signatures of Myocardial Infarction and Transverse Aortic Constriction in Aged Mouse Models., PMID:39502510
Spitz melanoma with MAP3K8::ABLIM1 rearrangement: a case report with review of the literature., PMID:39363234
miR-2467-3p/ABLIM1 Axis Mediates the Formation and Progression of Deep Vein Thrombosis by Regulating Inflammation and Oxidative Stress., PMID:39131807
GABRP inhibits the progression of oesophageal cancer by regulating CFTR: Integrating bioinformatics analysis and experimental validation., PMID:38989629
Pain/Stress, Mitochondrial Dysfunction, and Neurodevelopment in Preterm Infants., PMID:38286121
ABLIM1, a novel ubiquitin E3 ligase, promotes growth and metastasis of colorectal cancer through targeting IĸBα ubiquitination and activating NF-ĸB signaling., PMID:38228802
Genetic Pathways in Peritoneal Mesothelioma Tumorigenesis., PMID:37400148
Antigenic responses are hallmarks of fibrotic interstitial lung diseases independent of underlying etiologies., PMID:37214861
Distinct myofibre domains of the human myotendinous junction revealed by single-nucleus RNA sequencing., PMID:36924352
Actin-Binding LIM 1 (ABLIM1) Inhibits Glioblastoma Progression and Serves as a Novel Prognostic Biomarker., PMID:36583064
[Transcriptomic analysis of tuberculosis peptide-based vaccine MP3RT in humanized mice]., PMID:36097927
Transcriptomic Profile of Genes Regulating the Structural Organization of Porcine Atrial Cardiomyocytes during Primary In Vitro Culture., PMID:35885988
Self-construction of actin networks through phase separation-induced abLIM1 condensates., PMID:35858327
GSK-3β Localizes to the Cardiac Z-Disc to Maintain Length Dependent Activation., PMID:35168370
Effect and in silico characterization of genetic variants associated with severe spermatogenic disorders in a large Iberian cohort., PMID:33784440
Myelination defects in the medial prefrontal cortex of Fkbp5 knockout mice., PMID:33410216
Rictor promotes cell migration and actin polymerization through regulating ABLIM1 phosphorylation in Hepatocellular Carcinoma., PMID:33061800
LncRNA ZNF667-AS1 Promotes ABLIM1 Expression by Adsorbing micro RNA-1290 to Suppress Nasopharyngeal Carcinoma Cell Progression., PMID:32606725
Identification of hub-methylated differentially expressed genes in patients with gestational diabetes mellitus by multi-omic WGCNA basing epigenome-wide and transcriptome-wide profiling., PMID:31886571
Identification of Key Genes Potentially Related to Intervertebral Disk Degeneration by Microarray Analysis., PMID:31368816
abLIM1 constructs non-erythroid cortical actin networks to prevent mechanical tension-induced blebbing., PMID:30062045
Actin-binding LIM protein 1 regulates receptor activator of NF-κB ligand-mediated osteoclast differentiation and motility., PMID:29921413
Actin binding LIM 1 (abLIM1) negatively controls osteoclastogenesis by regulating cell migration and fusion., PMID:29904924
A random effects model for the identification of differential splicing (REIDS) using exon and HTA arrays., PMID:28545391
Personality as an intermediate phenotype for genetic dissection of alcohol use disorder., PMID:28054193
Whole-Genome Sequencing Suggests Schizophrenia Risk Mechanisms in Humans with 22q11.2 Deletion Syndrome., PMID:26384369
ABLIM1 splicing is abnormal in skeletal muscle of patients with DM1 and regulated by MBNL, CELF and PTBP1., PMID:25403273
Chromosome 10, frequently lost in human melanoma, encodes multiple tumor-suppressive functions., PMID:24453001
FUS-mediated alternative splicing in the nervous system: consequences for ALS and FTLD., PMID:23974990
miR-129-3p controls cilia assembly by regulating CP110 and actin dynamics., PMID:22684256
Differential gene regulation under altered gravity conditions in follicular thyroid cancer cells: relationship between the extracellular matrix and the cytoskeleton., PMID:21865726
Stromal upregulation of lateral epithelial adhesions: gene expression analysis of signalling pathways in prostate epithelium., PMID:21696611
Polymorphisms in ABLIM1 are associated with personality traits and alcohol dependence., PMID:21547531
Axon growth and guidance genes identify nascent, immature, and mature olfactory sensory neurons., PMID:20882566
Microarray-driven validation of reference genes for quantitative real-time polymerase chain reaction in a rat vocal fold model of mucosal injury., PMID:20670610
Analysis of the asymmetrically expressed Ablim1 locus reveals existence of a lateral plate Nodal-independent left sided signal and an early, left-right independent role for nodal flow., PMID:20487527
Microarray gene expression and immunohistochemistry analyses of adrenocortical tumors identify IGF2 and Ki-67 as useful in differentiating carcinomas from adenomas., PMID:19218281
Two novel members of the ABLIM protein family, ABLIM-2 and -3, associate with STARS and directly bind F-actin., PMID:17194709
Actin binding LIM protein 3 (abLIM3)., PMID:16328021
Genomic organisation and tissue specific expression of ABLIM2 gene in human, mouse and rat., PMID:16005990
Normal retinal development and retinofugal projections in mice lacking the retina-specific variant of actin-binding LIM domain protein., PMID:12849746
A POU domain transcription factor-dependent program regulates axon pathfinding in the vertebrate visual system., PMID:11163266
UNC-115, a conserved protein with predicted LIM and actin-binding domains, mediates axon guidance in C. elegans., PMID:9728919
Limatin (LIMAB1), an actin-binding LIM protein, maps to mouse chromosome 19 and human chromosome 10q25, a region frequently deleted in human cancers., PMID:9417918
Molecular characterization of abLIM, a novel actin-binding and double zinc finger protein., PMID:9245787
For research use only. Not for human or drug use.
