Catalog No.
YHK27701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser74-Lys186
Predicted molecular weight
15.34 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q96E93
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Killer cell lectin-like receptor subfamily G member 1, C-type lectin domain family 15 member A, ITIM-containing receptor MAFA-L, MAFA-like receptor, Mast cell function-associated antigen, KLRG1, CLEC15A, MAFA, MAFAL
TIM3 and TIGIT-expressing CD4 T cells are impacted by kidney transplantation and associated with risk of infection., PMID:40475763
Dual roles of IRE1α inhibition in reversing mitochondrial ROS-induced CD8+ T-cell senescence and exerting direct antitumor effects in multiple myeloma., PMID:40425229
Adjunctive beneficial effect of c-di-GMP, a STING agonist, in enhancing protective efficacy of TLR4-adjuvanted tuberculosis subunit vaccine formulations., PMID:40414893
KLRG1 expression induces functional exhaustion of NK cells in colorectal cancer patients., PMID:40372495
KLRG1 identifies regulatory T cells with mitochondrial alterations that accumulate with aging., PMID:40307497
Identification and regulation of circulating tumor-TCR-matched cytotoxic CD4+ lymphocytes by KLRG1 in bladder cancer., PMID:40299576
Molecular Hydrogen Capsule Therapy for Primary Biliary Cholangitis With Elevated IgG4: A Case Report on Immune Marker Normalization., PMID:40295001
miR-143-3p Promotes TSCM Differentiation and Inhibits Progressive T Cell Differentiation via Inhibiting ABL2 and PAG1., PMID:40282426
Effects of Anti-CD20 Antibody Therapy on Immune Cell Dynamics in Relapsing-Remitting Multiple Sclerosis., PMID:40214505
Mitochondrial damage is associated with an early immune response in inclusion body myositis., PMID:40193586
KLRG1 re-defines a leukemic clone of CD8 effector T cells sensitive to PI3K inhibitor in T cell large granular lymphocytic leukemia., PMID:40147444
Cytomegalovirus-associated CD57 + KLRG1 + CD8 + TEMRA T cells are associated with reduced risk of CMV viremia in kidney transplantation and chronic allograft dysfunction in lung transplantation., PMID:40120236
Expression of a single inhibitory member of the Ly49 receptor family is sufficient to license NK cells for effector functions., PMID:40085489
Cytotoxic KLRG1+ IL-7R- effector CD8+ T cells distinguish kidney transplant recipients controlling cytomegalovirus reactivation., PMID:40028342
Outer retina micro-inflammation is driven by T cell responses prior to retinal degeneration in early age-related macular degeneration., PMID:39975545
Epigenetic Signatures and Prognostic Biomarkers Analysis of Methylation-Driven Genes in Uterine Endometrial Carcinosarcoma., PMID:39957591
NK Cell Immaturity and NKp30 Expression Positively Correlate with Clinical Outcome in Multiple Myeloma Patients from the IFM2009 Clinical Trial., PMID:39931788
Regulation of NK cell development, maturation, and antitumor responses by the nuclear receptor NR2F6., PMID:39920136
Anti-correlation of KLRG1 and PD-1 expression in human tumor CD8 T cells., PMID:39832302
Prior influenza virus infection alleviates an arbovirus encephalitis by reducing viral titer, inflammation, and cellular infiltrates in the central nervous system., PMID:39817772
Strong immune responses and robust protection following a novel protein in adjuvant tuberculosis vaccine candidate., PMID:39805855
HLA-E/Mtb specific CD4+ and CD8+ T cells have a memory phenotype in individuals with TB infection., PMID:39790998
Recognition of Self and Viral Ligands by NK Cell Receptors., PMID:39748148
Activin A promoted the anti-tumor effect of ActRIIA high CD8+ T cells in mouse hepatoma., PMID:39727149
Kir6.1, a component of an ATP-sensitive potassium channel, regulates natural killer cell development., PMID:39687626
Esophageal ILC2s mediate abnormal epithelial remodeling in eosinophilic esophagitis via Areg-EGFR signaling., PMID:39653767
Modeling NK-cell lymphoma in mice reveals its cell-of-origin and microenvironmental changes and identifies therapeutic targets., PMID:39438472
TCF-1 and TOX regulate the memory formation of intestinal group 2 innate lymphoid cells in asthma., PMID:39245681
BCG immunization induced KLRG1+ NK cells show memory-like responses to mycobacterial and HIV antigens., PMID:39226746
Manganese-mediated potentiation of antitumor immune responses by enhancing KLRG1+ Macrophage function., PMID:39153309
Long-lived central memory γδ T cells confer protection against murine cytomegalovirus reinfection., PMID:38976755
Temporal Alterations in CD8+ T Cells During the Progression From Stage 1 to Stage 3 Type 1 Diabetes., PMID:38967999
Circulating KLRG1+ long-lived effector memory T cells retain the flexibility to become tissue resident., PMID:38941479
The role of KLRG1: a novel biomarker and new therapeutic target., PMID:38898461
CD28-CD57+ T cells from head and neck cancer patients produce high levels of cytotoxic granules and type II interferon but are not senescent., PMID:38887372
DNA demethylase Tet2 promotes the terminal maturation of natural killer cells., PMID:38869819
Airways epithelial exposure to Streptococcus pneumoniae in the presence of the alarmin IL-33 induces a novel subset of pro-inflammatory ILC2s promoting a mixed inflammatory response., PMID:38844678
miR-744-5p promotes T-cell differentiation via inhibiting STK11., PMID:38830518
KLRG1-expressing CD8+ T cells are exhausted and polyfunctional in patients with chronic hepatitis B., PMID:38776335
An intranasal nanoparticle vaccine elicits protective immunity against Mycobacterium tuberculosis., PMID:38704256
CXCR6-positive circulating mucosal-associated invariant T cells can identify patients with non-small cell lung cancer responding to anti-PD-1 immunotherapy., PMID:38698468
FcαRI (CD89) is upregulated on subsets of mucosal and circulating NK cells and regulates IgA-class specific signaling and functions., PMID:38677592
Expression of HLA-DR and KLRG1 enhances the cytotoxic potential and cytokine secretion capacity of CD3+ T cells in tuberculosis patients., PMID:38652959
Abatacept increases T cell exhaustion in early RA individuals who carry HLA risk alleles., PMID:38650930
KLRG1, Another Opportunity for a Breakthrough in MTCL., PMID:38568191
Persistence of a Skewed Repertoire of NK Cells in People with HIV-1 on Long-Term Antiretroviral Therapy., PMID:38551350
Improvement of hepatic innate immunity in chemically-injured livers to develop hepatocarcinoma by a serine type-protease inhibitors enriched extract from Chenopodium quinoa., PMID:38469889
Comparing anti-tumor and anti-self immunity in a patient with melanoma receiving immune checkpoint blockade., PMID:38443917
Combination of IL-33 with PD-1 blockade augment mILC2s-mediated anti-tumor immunity., PMID:38430390
STING activator 2'3'-cGAMP enhanced HSV-1-based oncolytic viral therapy., PMID:38400597
For research use only. Not for human or drug use.
