Catalog No.
EVV20901
Expression system
Mammalian Cells
Species
Varicella-zoster virus (strain Oka vaccine) (HHV-3) (Human herpesvirus 3)
Protein length
Asn18-Arg795
Predicted molecular weight
90.09 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q775J3
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Envelope glycoprotein H, gH, gH, ORF37
Targeted mutagenesis of the herpesvirus fusogen central helix captures transition states., PMID:38042814
A Variant Allele in Varicella-Zoster Virus Glycoprotein B Selected during Production of the Varicella Vaccine Contributes to Its Attenuation., PMID:35916400
The N-terminus of varicella-zoster virus glycoprotein B has a functional role in fusion., PMID:33411789
Varicella-zoster virus: molecular controls of cell fusion-dependent pathogenesis., PMID:33259590
Calcineurin phosphatase activity regulates Varicella-Zoster Virus induced cell-cell fusion., PMID:33216797
A glycoprotein B-neutralizing antibody structure at 2.8 Å uncovers a critical domain for herpesvirus fusion initiation., PMID:32811830
Increased incidence of herpes zoster in patients on renal replacement therapy cannot be explained by intrinsic defects of cellular or humoral immunity to varicella-zoster virus., PMID:30102958
Breadth and Functionality of Varicella-Zoster Virus Glycoprotein-Specific Antibodies Identified after Zostavax Vaccination in Humans., PMID:29743372
Dysregulated Glycoprotein B-Mediated Cell-Cell Fusion Disrupts Varicella-Zoster Virus and Host Gene Transcription during Infection., PMID:27795423
Role for the αV Integrin Subunit in Varicella-Zoster Virus-Mediated Fusion and Infection., PMID:27279620
Defensive Perimeter in the Central Nervous System: Predominance of Astrocytes and Astrogliosis during Recovery from Varicella-Zoster Virus Encephalitis., PMID:26491149
A site of varicella-zoster virus vulnerability identified by structural studies of neutralizing antibodies bound to the glycoprotein complex gHgL., PMID:25918416
The cytoplasmic domain of varicella-zoster virus glycoprotein H regulates syncytia formation and skin pathogenesis., PMID:24874654
An immunoreceptor tyrosine-based inhibition motif in varicella-zoster virus glycoprotein B regulates cell fusion and skin pathogenesis., PMID:23322733
Human anti-varicella-zoster virus (VZV) recombinant monoclonal antibody produced after Zostavax immunization recognizes the gH/gL complex and neutralizes VZV infection., PMID:23077312
Herpes virus fusion and entry: a story with many characters., PMID:22754650
Structure-function analysis of varicella-zoster virus glycoprotein H identifies domain-specific roles for fusion and skin tropism., PMID:22025718
Neutralizing anti-gH antibody of Varicella-zoster virus modulates distribution of gH and induces gene regulation, mimicking latency., PMID:21632752
Overview of varicella-zoster virus glycoproteins gC, gH and gL., PMID:20186613
Anti-glycoprotein H antibody impairs the pathogenicity of varicella-zoster virus in skin xenografts in the SCID mouse model., PMID:19828615
Characterization of neutralizing epitopes of varicella-zoster virus glycoprotein H., PMID:19073736
Comparative analyses of the 9 glycoprotein genes found in wild-type and vaccine strains of varicella-zoster virus., PMID:18419408
Delayed biosynthesis of varicella-zoster virus glycoprotein C: upregulation by hexamethylene bisacetamide and retinoic acid treatment of infected cells., PMID:16973558
Incorporation of three endocytosed varicella-zoster virus glycoproteins, gE, gH, and gB, into the virion envelope., PMID:15613328
Complete DNA sequence analyses of the first two varicella-zoster virus glycoprotein E (D150N) mutant viruses found in North America: evolution of genotypes with an accelerated cell spread phenotype., PMID:15194755
Regulation of varicella-zoster virus-induced cell-to-cell fusion by the endocytosis-competent glycoproteins gH and gE., PMID:14990707
Membrane fusion mediated by herpesvirus glycoproteins: the paradigm of varicella-zoster virus., PMID:12820183
A functional YNKI motif in the short cytoplasmic tail of varicella-zoster virus glycoprotein gH mediates clathrin-dependent and antibody-independent endocytosis., PMID:12634377
The out of Africa model of varicella-zoster virus evolution: single nucleotide polymorphisms and private alleles distinguish Asian clades from European/North American clades., PMID:12559782
Induction of cellular immunity to varicella-zoster virus glycoproteins tested with pernasal coadministration of Escherichia coli enterotoxin in mice., PMID:12526058
Expression of the simian varicella virus glycoprotein L and H., PMID:11890527
Varicella-zoster Virus gB and gE coexpression, but not gB or gE alone, leads to abundant fusion and syncytium formation equivalent to those from gH and gL coexpression., PMID:11533210
Multimeric humanized varicella-zoster virus antibody fragments to gH neutralize virus while monomeric fragments do not., PMID:11458003
Varicella-zoster virus gH:gL contains a structure reactive with the anti-human gamma chain of IgG near the glycosylation site., PMID:11161270
Varicella-zoster virus gE escape mutant VZV-MSP exhibits an accelerated cell-to-cell spread phenotype in both infected cell cultures and SCID-hu mice., PMID:10998331
Characterization of interaction of gH and gL glycoproteins of varicella-zoster virus: their processing and trafficking., PMID:10811938
Intracellular transport of varicella-zoster glycoproteins., PMID:9852965
Mutational analysis of the role of glycoprotein I in varicella-zoster virus replication and its effects on glycoprotein E conformation and trafficking., PMID:9343180
Chaperone functions common to nonhomologous Epstein-Barr virus gL and Varicella-Zoster virus gL proteins., PMID:8995697
Multiple regulatory effects of varicella-zoster virus (VZV) gL on trafficking patterns and fusogenic properties of VZV gH., PMID:8971025
Induction of varicella-zoster virus-neutralizing antibodies in mice by co-infection with recombinant vaccinia viruses expressing the gH or gL gene., PMID:8627224
DNA sequence of the simian varicella virus (SVV) gH gene and analysis of the SVV and varicella zoster virus gH transcripts., PMID:8546010
Cell surface expression and fusion by the varicella-zoster virus gH:gL glycoprotein complex: analysis by laser scanning confocal microscopy., PMID:7618278
Neutralization epitope of the varicella-zoster virus gH:gL glycoprotein complex., PMID:7510086
Entry and egress of varicella virus blocked by same anti-gH monoclonal antibody., PMID:8396811
Glycoproteins of varicella-zoster virus and their herpes simplex virus homologs., PMID:1664135
DNA sequence of the herpes simplex virus type 1 gene encoding glycoprotein gH, and identification of homologues in the genomes of varicella-zoster virus and Epstein-Barr virus., PMID:3012465
For research use only. Not for human or drug use.
