A fc-engineered NKG2D × B7-H3 bispecific antibody enhances the antitumor activity by orchestrating cytotoxic lymphocytes., PMID:40516256
Crystallographic fragment screening reveals ligand hotspots in TRIM21 PRY-SPRY domain., PMID:40514378
Identification of a direct interaction between the Fab domains of IgG antibodies and human FcRn upon IgG-FcRn complex formation., PMID:40506471
Drug survival, long-term safety and efficacy of anti-TNF-alpha biosimilars: a monocentric retrospective study., PMID:40485573
Luspatercept for the treatment of lower-risk myelodysplastic syndrome with SF3B1 mutation: a real-world single-center research in China., PMID:40474348
Pan-H7 influenza human antibody virus neutralization depends on avidity and steric hindrance., PMID:40471690
Efgartigimod combined with steroids as a fast-acting therapy for anti-SRP immune-mediated necrotizing myopathy., PMID:40470493
Production of functional recombinant antibodies in Dictyostelium discoideum., PMID:40468350
Higher order receptor clustering due to the IgG3 subclass is necessary for TLR4 signaling and tolerance induction by novel human anti-TLR4 antibodies., PMID:40464120
Fc-effector functional antibody assays for SARS-CoV-2 variants of concern., PMID:40463385
Fc-optimized anti-CTLA-4 antibodies increase tumor-associated high endothelial venules and sensitize refractory tumors to PD-1 blockade., PMID:40460830
Real-world evaluation of the efficacy and safety of switching from weekly dulaglutide to weekly semaglutide: The SEMA-SWITCH study., PMID:40450456
A bioactive soluble recombinant mouse LIGHT promotes effective tumor immune cell infiltration delaying tumor growth., PMID:40457031
Antibody-Fab and -Fc features promote Mycobacterium tuberculosis restriction., PMID:40449485
Etanercept, a peripherally restricted TNF inhibitor, enhances cocaine-induced locomotor behaviors in male, but not female, rats., PMID:40446442
Cryo-EM structures of HCV E2 glycoprotein bound to neutralizing and non-neutralizing antibodies determined using bivalent Fabs as fiducial markers., PMID:40442315
Psoriasis complicated with polymyositis successfully treated with Ixekizumab: A case report., PMID:40441209
Impact of Vaccine-Elicited Anti-Spike IgG4 Antibodies on Fc-Effector Functions Against SARS-CoV-2., PMID:40431678
Integrating Biochemical and Computational Approaches Reveal Structural Insights in Trastuzumab scFv-Fc Antibody Engineering., PMID:40427499
Balancing Reactivity and Specificity: Fc-Binding O-Acyl Hydroxamate Reagents for Site-Selective Antibody Labeling at Lys248., PMID:40423997
Pharmacovigilance analysis of neurological adverse events associated with GLP-1 receptor agonists based on the FDA Adverse Event Reporting System., PMID:40413246
The Fusion Protein MuSK-Fc Functions as a Decoy to Block the Binding of Anti-MuSK Antibodies to MuSK., PMID:40411208
Efficacy, Safety, and Future of GLP-1 Receptor Agonists: A Systematic Literature Review and Meta-Analysis., PMID:40409279
Fate of Stressed Oligoclonal Antibodies Tracked by Fluorescence Cross-Correlation Spectroscopy: IgG Aggregation Proceeds across the Species Barrier., PMID:40408563
Real world study in Italian public hospital with Efgartigimod in patients affected by generalized myasthenia gravis: influence of clinical and serological factors., PMID:40401017
Antibody Labeling With FITC Facilitates Controlled Release From Peptide Hydrogels Bearing Fc-Binding Motifs., PMID:40400208
Dual therapy for amanita phalloides-induced acute liver failure in mice: A combination of etanercept and alpha-1 antitrypsin., PMID:40398510
Development and characterization of AD-214, an anti-CXCR4 i-body-Fc fusion for the treatment of idiopathic pulmonary fibrosis., PMID:40395177
Synovial Gene expression after Hemarthrosis differs between FVIII-deficient mice treated with recombinant FVIII or FVIII-Fc Fusion Protein., PMID:40388523
Molecular determinants of sialylated IgG anti-inflammatory activity., PMID:40377989
Engineering of long-acting human growth hormone-Fc fusion proteins: Effects of valency, fusion position, and linker design on pharmacokinetics and efficacy., PMID:40373007
Increasing the developability of lambda chain antibodies: engineering to confer protein L binding activity and its consequences., PMID:40368210
The double edge of erythropoietic modulation in thalassaemia., PMID:40364548
Comparative evaluation of chelators in the context of analysis of antibody oxidative stability., PMID:40345531
Sample-sparing multiplexed antibody Fc biomarker discovery using a reconfigurable integrated microfluidic platform., PMID:40337849
New Approvals in Low- and Intermediate-Risk Myelodysplastic Syndromes., PMID:40334184
Healthcare resource utilization of patients with lower-risk myelodysplastic syndromes treated with luspatercept versus erythropoiesis-stimulating agents: a United States healthcare claims database study., PMID:40329816
Comparison of antibody-scTRAIL Fc fusion proteins with varying valency for EGFR and TRAIL receptors., PMID:40328809
A phase 1, randomized, double-blind, placebo-controlled trial investigating the safety, tolerability, pharmacokinetics, and pharmacodynamics of KN056 (a recombinant human GLP-1 variant Fc fusion protein) in healthy Chinese participants., PMID:40328758
Leveraging neonatal Fc receptor (FcRn) to enhance antibody transport across the blood brain barrier., PMID:40319060
Characteristic profiling of CHO-cell expressed MERS-CoV RBD-Fc., PMID:40318720
Comparison of the ACE2 receptor and monoclonal antibodies immobilisation strategies for the sensitive detection of SARS-CoV-2 variants of concern., PMID:40316389
Acute splenomegaly, haemolysis, and thrombocytopenia following luspatercept initiation in a patient with transfusion-dependent thalassaemia: A case report., PMID:40307204
Antibody oxidation and impact of formulation: A high-throughput screening approach., PMID:40306556
Design of an Fc Mutation to Abrogate Fcγ Receptor Binding Based on Residue Interaction Network Analysis., PMID:40300090
TNF-α antagonist alleviates muscular layer enlargement but does not prevent myenteric neuronal loss in the colon of streptozotocin-induced diabetic rats., PMID:40288461
Impact of excess weight on clinical features of psoriasis and efficacy of biologic therapies in children with severe psoriasis: Analysis of data from the BiPe cohorts., PMID:40286464
Effects of GLP-1 Analogues and Agonists on the Gut Microbiota: A Systematic Review., PMID:40284168
Comprehensive Characterization of IgG2 Disulfide Isoforms Using Native Cation Exchange Chromatography-Mass Spectrometry and Peptide Mapping., PMID:40273039
Enhancing the Protein Stability of an Anticancer VHH-Fc Heavy Chain Antibody through Computational Modeling and Variant Design., PMID:40271725
For research use only. Not for human or drug use.
