Catalog No.
RHK98201
Species reactivity
Human
Host species
Human
Isotype
IgG1
Clonality
Monoclonal
Target
NgR, Nogo receptor, Reticulon-4 receptor, RTN4R, Nogo-66 receptor, NOGOR
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9BZR6
Applications
ELISA, FCM, IF, IP, SPR, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
M5
Glucopeptides derived from myelin-relevant proteins and hyperglucosylated nontypeable Haemophilus influenzae bacterial adhesin cross-react with multiple sclerosis specific antibodies: A step forward in the identification of native autoantigens in multiple sclerosis., PMID:36597597
An in-depth analysis reveals two new genetic variants on 22q11.2 associated with vitiligo in the Chinese Han population., PMID:34350550
B-cells expressing NgR1 and NgR3 are localized to EAE-induced inflammatory infiltrates and are stimulated by BAFF., PMID:33536561
Identification of a new functional domain of Nogo-A that promotes inflammatory pain and inhibits neurite growth through binding to NgR1., PMID:32598099
Nogo receptor antagonist LOTUS exerts suppression on axonal growth-inhibiting receptor PIR-B., PMID:32201946
Nogo receptor 1 is expressed by nearly all retinal ganglion cells., PMID:29768445
The Subventricular Zone Response to Stroke Is Not a Therapeutic Target of Anti-Nogo-A Immunotherapy., PMID:28789474
Fc Receptor-like 5 Expression Distinguishes Two Distinct Subsets of Human Circulating Tissue-like Memory B Cells., PMID:27076679
Association of cerebrospinal fluid levels of lateral olfactory tract usher substance (LOTUS) with disease activity in multiple sclerosis., PMID:25437093
Anti-Nogo-A antibody: a treatment option for neurogenic lower urinary tract dysfunction?, PMID:25430943
Therapeutics targeting Nogo-A hold promise for stroke restoration., PMID:23394537
Changes in expression of Nogo receptor 1 in hippocampus and cortex after cardiopulmonary resuscitation in rats., PMID:23158614
PirB restricts neuronal regeneration in developing rat brain following hypoxia-ischemia., PMID:22580685
Limiting multiple sclerosis related axonopathy by blocking Nogo receptor and CRMP-2 phosphorylation., PMID:22544872
The effect of growth factors and soluble Nogo-66 receptor protein on transplanted neural stem/progenitor survival and axonal regeneration after complete transection of rat spinal cord., PMID:22236767
Expression and function of myelin-associated proteins and their common receptor NgR on oligodendrocyte progenitor cells., PMID:22227458
Nogo-66 inhibits adhesion and migration of microglia via GTPase Rho pathway in vitro., PMID:22145612
Soluble Nogo-66 receptor prevents synaptic dysfunction and rescues retinal ganglion cell loss in chronic glaucoma., PMID:21948553
The use of a gold nanoparticle-based adjuvant to improve the therapeutic efficacy of hNgR-Fc protein immunization in spinal cord-injured rats., PMID:21784510
Targeting the Nogo receptor complex in diseases of the central nervous system., PMID:21110803
Hyaluronic acid hydrogel modified with nogo-66 receptor antibody and poly-L-lysine to promote axon regrowth after spinal cord injury., PMID:20725955
Effect of combined treatment with methylprednisolone and Nogo-A monoclonal antibody after rat spinal cord injury., PMID:20515570
Neurites regrowth of cortical neurons by GSK3beta inhibition independently of Nogo receptor 1., PMID:20374426
Localization of an axon growth inhibitory molecule Nogo and its receptor in the spinal cord of mouse embryos., PMID:19833111
Viability and differentiation of neural precursors on hyaluronic acid hydrogel scaffold., PMID:19530168
PirB is a functional receptor for myelin inhibitors of axonal regeneration., PMID:18988857
Immunization with recombinant Nogo-66 receptor (NgR) promotes axonal regeneration and recovery of function after spinal cord injury in rats., PMID:18930141
An experimental test of stroke recovery by implanting a hyaluronic acid hydrogel carrying a Nogo receptor antibody in a rat model., PMID:18458480
An immunofluorescence-histochemistry study of the Nogo receptor in the rat retina during postnatal development., PMID:17984503
[NgR expression in oligodendrocyte precursor cells and its changes after oxygen & glucose deprivation in neonatal rats]., PMID:17937855
Nogo enhances the adhesion of olfactory ensheathing cells and inhibits their migration., PMID:17488779
Epitope mapping of the neuronal growth inhibitor Nogo-A for the Nogo receptor and the cognate monoclonal antibody IN-1 by means of the SPOT technique., PMID:17486692
Localisation and expression of a myelin associated neurite inhibitor, Nogo-A and its receptor Nogo-receptor by mammalian CNS cells., PMID:17428512
DNA vaccine against NgR promotes functional recovery after spinal cord injury in adult rats., PMID:17362886
Detection of anti-Nogo receptor autoantibody in the serum of multiple sclerosis and controls., PMID:17295709
Increased expression of the Nogo receptor in the hippocampus and its relation to the neuropathology in Alzheimer's disease., PMID:17188332
Chimeric rabbit/human Fab and IgG specific for members of the Nogo-66 receptor family selected for species cross-reactivity with an improved phage display vector., PMID:17140598
[Preparation and identification of rabbit antibody against LRR of Nogo-66 receptor (NgR)]., PMID:16948913
Selective temporal and regional alterations of Nogo-A and small proline-rich repeat protein 1A (SPRR1A) but not Nogo-66 receptor (NgR) occur following traumatic brain injury in the rat., PMID:16321384
The enhancement of cell adherence and inducement of neurite outgrowth of dorsal root ganglia co-cultured with hyaluronic acid hydrogels modified with Nogo-66 receptor antagonist in vitro., PMID:16298084
Effect of combined treatment with methylprednisolone and soluble Nogo-66 receptor after rat spinal cord injury., PMID:16101740
Why do Nogo/Nogo-66 receptor gene knockouts result in inferior regeneration compared to treatment with neutralizing agents?, PMID:16092935
Nogo-66 receptor at cerebellar cortical glia gap junctions in the rat., PMID:16088223
Identification of a functional epitope of the Nogo receptor by a combinatorial approach using ribosome display., PMID:16061255
Hyaluronic acid hydrogel as Nogo-66 receptor antibody delivery system for the repairing of injured rat brain: in vitro., PMID:15653130
Nogo-66 and myelin-associated glycoprotein (MAG) inhibit the adhesion and migration of Nogo-66 receptor expressing human glioma cells., PMID:15312170
Regulation of Nogo and Nogo receptor during the development of the entorhino-hippocampal pathway and after adult hippocampal lesions., PMID:15121177
Nogo-A inhibits neurite outgrowth and cell spreading with three discrete regions., PMID:12843238
Myelin-associated glycoprotein interacts with the Nogo66 receptor to inhibit neurite outgrowth., PMID:12160746
Nogo-66 receptor antagonist peptide promotes axonal regeneration., PMID:12037567
For research use only. Not for human or drug use.
