Please ensure Javascript is enabled for purposes of website accessibility
Home / Products / Antibody / Recombinant Antibody

Anti-Alpha-synuclein Antibody (N335/10)

Catalog #:   RHN24601 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: IHC, WB
Overview

Catalog No.

RHN24601

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

Sph1, Alpha-synuclein-interacting protein, SNCAIP, Synphilin-1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Applications

IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

N335/10

Data Image
References

α-Synuclein Pathology in Synucleinopathies: Mechanisms, Biomarkers, and Therapeutic Challenges., PMID:40508212

Generation of iPSC lines with tagged α-synuclein for visualization of endogenous protein in human cellular models of neurodegenerative disorders., PMID:40456614

Hippocampal subfields: volume, neuropathological vulnerability and cognitive decline in Alzheimer's and Parkinson's disease., PMID:40448161

Multiplex Immunofluorescent Analysis of Alpha-Synuclein in Nigral Lewy Bodies With Heat-Induced Antibody Stripping Reveals an Intricate Multilayered Structure., PMID:40442873

Nanoplatforms Targeting Intrinsically Disordered Protein Aggregation for Translational Neuroscience Applications., PMID:40423094

Rational selection of the monoclonal α-synuclein antibody amlenetug (Lu AF82422) for the treatment of α-synucleinopathies., PMID:40404755

Fluid biomarkers in atypical Parkinsonism: current state and future perspectives., PMID:40392273

Electro-Sensing Analysis for Parkinson's Disease Biomarker on Dual-Electrode Surface: Complemented by Molecular Docking., PMID:40384391

Nanomaterial Enhances the Performance of Amyloid-beta Biosensing for Alzheimer's Disease Diagnosis., PMID:40337966

Targeted proteomic biomarker profiling using NULISA in a cohort enriched with risk for Alzheimer's disease and related dementias., PMID:40318118

Abundant non-inclusion α-synuclein pathology in Lewy body-negative LRRK2-mutant cases., PMID:40314782

Facile generation of drug-like conformational antibodies specific for amyloid fibrils., PMID:40301692

Interactions of Therapeutic Antibodies With Presynaptically-Released Misfolded Proteins in Neurodegenerative Diseases. A Spatial Monte-Carlo Simulation Study., PMID:40296445

Hypothermia Shifts Neurodegeneration Phenotype in Neonatal Human Hypoxic-Ischemic Encephalopathy but Not in Related Piglet Models: Possible Relationship to Toxic Conformer and Intrinsically Disordered Prion-like Protein Accumulation., PMID:40277911

Evaluation of 6 monoclonal antibodies against Ser129-phosphorylated α-synuclein: Critical role of proteinase K antigen retrieval and superior sensitivity of the D1R1R clone in human skin biopsies., PMID:40261899

PET tracer development for imaging α-synucleinopathies., PMID:40227383

Fibril fuzzy coat is important for α-synuclein pathological transmission activity., PMID:40215967

A fragment of Calpain-1 cleaved α-Synuclein quantified in serum is upregulated in patients with Parkinson's disease., PMID:40204767

Proximity proteomics reveals unique and shared pathological features between multiple system atrophy and Parkinson's disease., PMID:40122840

HC070, a Transient Receptor Potential Canonical 5 (TRPC5) Channels Inhibitor Ameliorated α-synuclein Preformed Fibrils-Induced Parkinson's Disease: A Neurobehavioural and Mechanistic Study., PMID:40066713

Overlapping presence of β-amyloid, tau, p-tau, and α-synuclein in skin nerve fibers in Alzheimer's disease., PMID:40042672

Autoantibodies against α-synuclein inhibit its aggregation and cytotoxicity., PMID:40037001

Cell-Division-Independent Rapid Expression of DNA Delivered with α-Synuclein-Gold Nanoparticle Conjugates., PMID:40014054

Targeted Raman Visualization and Mitigation of α-Synuclein Amyloidogenesis in Living Zebrafish by a Nanobody-Decorated Polydiacetylene., PMID:39996265

Prasinezumab slows motor progression in Parkinsons disease: beyond the clinical data., PMID:39971932

Multimer Detection System: A Universal Assay System for Differentiating Protein Oligomers from Monomers., PMID:39940966

Proteolytic therapeutic modalities for amyloidoses: Insights into immunotherapy, PROTAC, and photo-oxygenation., PMID:39939242

Altered ATP13A2/PARK9 Levels Influence α-Synuclein Accumulation in Neurons via Phagocytosis and Secretion in Glial Cells., PMID:39936955

An autopsy case of coexisting spinal and bulbar muscular atrophy and multiple system atrophy., PMID:39916440

The roles of functional bacterial amyloids in neurological physiology and pathophysiology: Pros and cons for neurodegeneration., PMID:39909290

Neuronal α-synuclein toxicity is the key driver of neurodegeneration in multiple system atrophy., PMID:39908177

Retraction Notice to: ESCRT-mediated Uptake and Degradation of Brain-targeted α-synuclein Single Chain Antibody Attenuates Neuronal Degeneration In Vivo., PMID:39900036

Quantification of cinpanemab (BIIB054) binding to α-synuclein in cerebrospinal fluid of phase 1 single ascending dose samples., PMID:39892989

Biomarker treatment effects in two phase 3 trials of gantenerumab., PMID:39887500

Tracing TMEM106B fibril deposition in aging and Parkinson's disease with dementia brains., PMID:39872397

Correction to α-synuclein conformational antibodies fused to penetratin are effective in models of Lewy body disease., PMID:39869484

Distinct subcellular localization of tau and alpha-synuclein in lewy body disease., PMID:39838428

Multi-Targeting Macrocyclic Peptides as Nanomolar Inhibitors of Self- and Cross-Seeded Amyloid Self-Assembly of α-Synuclein., PMID:39822034

Retraction Notice to "Differential effects of immunotherapy with antibodies targeting α-synuclein oligomers and fibrils in a transgenic model of synucleinopathy" [Neurobiology of Disease 104 (2017) 85-96]., PMID:39818529

Nuclear Alpha-Synuclein in Parkinson's Disease and the Malignant Transformation in Melanoma., PMID:39816956

A nanoparticle-based wireless deep brain stimulation system that reverses Parkinson's disease., PMID:39813330

The interaction of tPA with NMDAR1 drives neuroinflammation and neurodegeneration in α-synuclein-mediated neurotoxicity., PMID:39810216

Neuronal LAG3 facilitates pathogenic α-synuclein neuron-to-neuron propagation., PMID:39803449

A Phase 2b, multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of intravenous prasinezumab in early-stage Parkinson's disease (PADOVA): Rationale, design, and baseline data., PMID:39798255

Artificial Intelligence-Based Methodologies for Early Diagnostic Precision and Personalized Therapeutic Strategies in Neuro-Ophthalmic and Neurodegenerative Pathologies., PMID:39766465

N-terminus α-synuclein detection reveals new and more diverse aggregate morphologies in multiple system atrophy and Parkinson's disease., PMID:39726015

Co-pathologies modify hippocampal protein accumulation patterns in neurodegenerative diseases., PMID:39711489

A brain-penetrant bispecific antibody lowers oligomeric alpha-synuclein and activates microglia in a mouse model of alpha-synuclein pathology., PMID:39676023

An update on immune-based alpha-synuclein trials in Parkinson's disease., PMID:39666171

What is the future for dementia with Lewy bodies?, PMID:39666092

Datasheet
$ 328
Product specifications
100 μg 328 1 mg 1640

Contact Information

Order: order@antibodysystem.com

Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

Need help with your order?

Find out more about placing an order here

Anti-Alpha-synuclein Antibody (N335/10) [RHN24601]
Terms of sale Website terms of use Cookie policy Privacy
Copyright © 2025 AntibodySystem SAS. All Rights Reserved.            All Products are for Research Use Only