Catalog No.
RHG05303
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
N-methyl-D-aspartate receptor subunit NR1, GluN1, Glutamate [NMDA] receptor subunit zeta-1, Glutamate receptor ionotropic, NMDA 1, NMD-R1, GRIN1, NMDAR1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
N308/1
Development of anti-NMDA receptor encephalitis in a patient with multiple sclerosis., PMID:40345675
Input-Specific Localization of NMDA Receptor GluN2 Subunits in Thalamocortical Neurons., PMID:40123534
Bridging the gap: insights into sensorimotor deficits in NMDA receptor antibody encephalitis., PMID:40026244
Assembly and architecture of endogenous NMDA receptors in adult cerebral cortex and hippocampus., PMID:39855198
Molecular scalpels dissect new GluN1 hot spots in anti-NMDA receptor encephalitis., PMID:39752539
Disrupted callosal connectivity underlies long-lasting sensory-motor deficits in an NMDA receptor antibody encephalitis mouse model., PMID:39739422
Quantitative Electroencephalography Biomarkers in Patients With Anti-N-methyl-D-aspartate Receptor Encephalitis: A Case-Control Study., PMID:39724935
Neuro-immunobiology and treatment assessment in a mouse model of anti-NMDAR encephalitis., PMID:39719005
Anti-NMDAR1 antibody impairs dendritic branching in immature cultured neurons., PMID:39434510
Chaihu Guizhi Decoction prevents cognitive, memory impairments and sensorimotor gating deficit induced by N-methyl-d-aspartate receptor antibody in mice., PMID:39278296
Input-specific localization of NMDA receptor GluN2 subunits in thalamocortical neurons., PMID:39229083
Structural basis for antibody-mediated NMDA receptor clustering and endocytosis in autoimmune encephalitis., PMID:39227720
Structural and functional mechanisms of anti-NMDAR autoimmune encephalitis., PMID:39227719
H-intensity scale score to estimate CSF GluN1 antibody titers with one-time immunostaining using a commercial assay., PMID:38745654
Expression and Purification of Mammalian NMDA Receptor Protein for Functional Characterization., PMID:38727900
Impaired functional connectivity of the hippocampus in translational murine models of NMDA-receptor antibody associated neuropsychiatric pathology., PMID:37875549
Human NMDAR autoantibodies disrupt excitatory-inhibitory balance, leading to hippocampal network hypersynchrony., PMID:37768823
Optimizing animal models of autoimmune encephalitis using active immunization., PMID:37520559
Transfer of patient's peripheral blood mononuclear cells (PBMCs) disrupts blood-brain barrier and induces anti-NMDAR encephalitis: a study of novel humanized PBMC mouse model., PMID:37443034
Visualizing the triheteromeric N-methyl-D-aspartate receptor subunit composition., PMID:37292368
Subunit-Dependent Surface Mobility and Localization of NMDA Receptors in Hippocampal Neurons Measured Using Nanobody Probes., PMID:37286354
Quantitative analysis of NMDA receptor subunits proteins in mouse brain., PMID:36913980
β2-microglobulin functions as an endogenous NMDAR antagonist to impair synaptic function., PMID:36868208
NMDA-receptor-Fc-fusion constructs neutralize anti-NMDA receptor antibodies., PMID:36866449
Overlapping anti-NMDAR encephalitis and multiple sclerosis: A case report and literature review., PMID:36793718
Myelinating Co-Culture as a Model to Study Anti-NMDAR Neurotoxicity., PMID:36613687
Atypical psychiatric presentation of relapsing anti-N-methyl-D-aspartate receptor encephalitis in childhood., PMID:36426777
GluN1 antibody causes behavioral deficits in prepulse inhibition and memory through CaMKIIβ signaling., PMID:36417808
Development and characterization of functional antibodies targeting NMDA receptors., PMID:35177668
Cellular prion protein in human plasma-derived extracellular vesicles promotes neurite outgrowth via the NMDA receptor-LRP1 receptor system., PMID:35090893
[Encephalitis due to antibodies against the N-methyl-D-aspartate receptor secondary to ovarian teratoma in a pediatric patient]., PMID:35068130
Current Status of Biomarkers in Anti-N-Methyl-D-Aspartate Receptor Encephalitis., PMID:34884930
Lipid bilayers regulate allosteric signal of NMDA receptor GluN1 C-terminal domain., PMID:34781056
Longitudinal analysis of regional brain changes in anti-NMDAR encephalitis: a case report., PMID:34706674
Evaluation of the concordance between GluN1-GluN2 heteromer live-cell-based assay and GluN1 monomer biochip kit assay on anti-NMDAR autoantibody detection., PMID:34560071
The diverse and complex modes of action of anti-NMDA receptor autoantibodies., PMID:34081993
[Anti-NMDA Receptor Encephalitis]., PMID:34006693
Anti-NMDA receptor encephalitis: a review of mechanistic studies., PMID:33815666
Anti-NMDAR encephalitis induced in mice by active immunization with a peptide from the amino-terminal domain of the GluN1 subunit., PMID:33612107
Exploratory investigation on antibodies to GluN1 and cognitive dysfunction in patients with chronic autoimmune psychosis., PMID:33359543
Expression of the ionotropic glutamate receptors on neuronostatin neurons in the periventricular nucleus of the hypothalamus., PMID:33330967
An exploratory investigation of antibodies to NMDA-type glutamate receptor subunits in serum and cerebrospinal fluid among psychiatric patients with anti-thyroid antibodies., PMID:33319115
Ionotropic glutamate receptors in platelets: opposing effects and a unifying hypothesis., PMID:33284715
Characteristics of internalization of NMDA-type GluRs with antibodies to GluN1 and GluN2B., PMID:33091764
Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is associated with IRF7, BANK1 and TBX21 polymorphisms in two populations., PMID:33065758
Glucose transporter type 1 deficiency syndrome associated with autoantibodies to glutamate receptors., PMID:32591173
Astrocytes and their potential role in anti-NMDA receptor encephalitis., PMID:32085980
N-Methyl-D-Aspartate Receptor Antibodies in Autoimmune Encephalopathy Alter Oligodendrocyte Function., PMID:32052483
Serum Anti-NMDA (N-Methyl-D-Aspartate)-Receptor Antibodies and Long-Term Clinical Outcome After Stroke (PROSCIS-B)., PMID:31526121
Human gestational N-methyl-d-aspartate receptor autoantibodies impair neonatal murine brain function., PMID:31325344
For research use only. Not for human or drug use.
