Catalog No.
RHD49302
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
HGK5, Voltage-gated K(+) channel HuKIII, HLK3, KCNA3, Potassium voltage-gated channel subfamily A member 3, HPCN3, Voltage-gated potassium channel subunit Kv1.3
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
L23/27
Structure-Function Relationship of a Novel MTX-like Peptide (MTX1) Isolated and Characterized from the Venom of the Scorpion Maurus palmatus., PMID:39408804
Anti-Inflammatory Effect of Licochalcone A via Regulation of ORAI1 and K+ Channels in T-Lymphocytes., PMID:34639190
The Kv1.3 K+ channel in the immune system and its "precision pharmacology" using peptide toxins., PMID:34554500
Immune Checkpoint Inhibitors Regulate K+ Channel Activity in Cytotoxic T Lymphocytes of Head and Neck Cancer Patients., PMID:34512366
Therapeutic Antibodies Targeting Potassium Ion Channels., PMID:33963460
Immunomagnetic separation is a suitable method for electrophysiology and ion channel pharmacology studies on T cells., PMID:33356811
A role for TASK2 channels in the human immunological synapse., PMID:33169379
PD1 blockade enhances K+ channel activity, Ca2+ signaling, and migratory ability in cytotoxic T lymphocytes of patients with head and neck cancer., PMID:33060146
Role of Kv1.3 Channels in Platelet Functions and Thrombus Formation., PMID:32787516
Dlg1 Maintains Dendritic Cell Function by Securing Voltage-Gated K+ Channel Integrity., PMID:31028120
Regulation of the voltage gated K channel Kv1.3 by recombinant human klotho protein., PMID:25571875
Differential expression of the Kv1 voltage-gated potassium channel family in the rat nephron., PMID:24948003
Characterization of the first K⁺ channel blockers from the venom of the Moroccan scorpion Buthus occitanus Paris., PMID:23523531
The antibody targeting the E314 peptide of human Kv1.3 pore region serves as a novel, potent and specific channel blocker., PMID:22558454
Coexpression of high-voltage-activated ion channels Kv3.4 and Cav1.2 in pioneer axons during pathfinding in the developing rat forebrain., PMID:22473424
Effect of potassium channel opener pinacidil on the contractions elicited electrically or by noradrenaline in the human radial artery., PMID:21236249
Characterisation of K+ currents in the C8-B4 microglial cell line and their regulation by microglia activating stimuli., PMID:19710528
Molecular mechanisms for Kv1.3 potassium channel current inhibition by CD3/CD28 stimulation in Jurkat T cells., PMID:18611390
High-throughput profiling of ion channel activity in primary human lymphocytes., PMID:18433147
An intermediate-conductance Ca(2+)-activated K (+) channel mediates B lymphoma cell cycle progression induced by serum., PMID:17429684
AMA production in primary biliary cirrhosis is promoted by the TLR9 ligand CpG and suppressed by potassium channel blockers., PMID:17256753
Potassium channels Kv1.3 and Kv1.5 are expressed on blood-derived dendritic cells in the central nervous system., PMID:16729292
Detection of channel proximity by nanoparticle-assisted delaying of toxin binding; a combined patch-clamp and flow cytometric energy transfer study., PMID:15375639
K+ channel expression during B cell differentiation: implications for immunomodulation and autoimmunity., PMID:15240664
A voltage-gated K(+) current in renal inner medullary collecting duct cells., PMID:14684382
Kv1.1 and Kv1.3 channels contribute to the delayed-rectifying K+ conductance in rat choroid plexus epithelial cells., PMID:14602579
Adult alveolar epithelial cells express multiple subtypes of voltage-gated K+ channels that are located in apical membrane., PMID:12606310
Contributions of Kv1.2, Kv1.5 and Kv2.1 subunits to the native delayed rectifier K(+) current in rat mesenteric artery smooth muscle cells., PMID:12127166
Molecular determinants of emerging excitability in rat embryonic motoneurons., PMID:12015418
Potassium channel KV alpha1 subunit expression and function in human detrusor muscle., PMID:11912453
K(V)alpha1 channels in murine arterioles: differential cellular expression and regulation of diameter., PMID:11514271
Immunohistochemical study on the distribution of six members of the Kv1 channel subunits in the rat cerebellum., PMID:11259775
K+ channels and the microglial respiratory burst., PMID:11245596
Altered outward-rectifying K(+) current reveals microglial activation induced by HIV-1 Tat protein., PMID:11241736
KV1.1 K(+) channels identification in human breast carcinoma cells: involvement in cell proliferation., PMID:11097830
KChAP as a chaperone for specific K(+) channels., PMID:10794667
Heterogeneous expression of voltage-gated potassium channels of the shaker family (Kv1) in oligodendrocyte progenitors., PMID:10528121
Subunit composition of Kv1 channels in human CNS., PMID:10428084
Expression of Kv1.5 K+ channels in activated microglia in vivo., PMID:9814821
Subunit composition of brain voltage-gated potassium channels determined by hongotoxin-1, a novel peptide derived from Centruroides limbatus venom., PMID:9446567
The sensitivity of the human Kv1.3 (hKv1.3) lymphocyte K+ channel to regulation by PKA and PKC is partially lost in HEK 293 host cells., PMID:9435274
Evidence for interaction between transmembrane segments in assembly of Kv1.3., PMID:9398279
Complex subunit assembly of neuronal voltage-gated K+ channels. Basis for high-affinity toxin interactions and pharmacology., PMID:9346893
Margatoxin binds to a homomultimer of K(V)1.3 channels in Jurkat cells. Comparison with K(V)1.3 expressed in CHO cells., PMID:9132027
Tyrosine phosphorylation-dependent suppression of a voltage-gated K+ channel in T lymphocytes upon Fas stimulation., PMID:8702786
Immunological Identification of the Shaker-Related Kv1.3 Potassium Channel Protein in T and B Lymphocytes, and Detection of Related Proteins in Flies and Yeast., PMID:8447822
For research use only. Not for human or drug use.
