Anti-Beta-1 adrenergic receptor Antibody (N477/45)

Catalog No.

RHC34401

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

Beta-1 adrenoreceptor, ADRB1, Beta-1 adrenergic receptor, ADRB1R, B1AR, Beta-1 adrenoceptor

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Applications

IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

N477/45

Autoimmune Antibodies in Orthostatic Intolerance Syndromes., PMID:40432440

Activation dynamics traced through a G protein-coupled receptor by 81 1H-15N NMR probes., PMID:40373152

Oroxin B Resembles Bisoprolol in Attenuating Beta1-Adrenergic Receptor Autoantibody-Induced Atrial Remodelling via the PTEN/AKT/mTOR Signalling Pathway., PMID:39648364

β2-adrenergic receptor activation decreases the mechanical sensitivity of rat masticatory muscle afferent fibres., PMID:38894554

Pioglitazone Alleviates β1-Adrenergic Receptor Antibody-Induced Atrial Fibrillation Susceptivity via Mitigation of PPAR-γ-Mediated Metabolic Inflexibility., PMID:38818915

β1 Adrenergic Receptor Autoantibodies and IgG Subclasses: Current Status and Unsolved Issues., PMID:37754819

S100a9 inhibits Atg9a transcription and participates in suppression of autophagy in cardiomyocytes induced by β1-adrenoceptor autoantibodies., PMID:37723445

Clinical and prognostic associations of autoantibodies recognizing adrenergic/muscarinic receptors in patients with heart failure., PMID:36883593

Receptor autoantibodies: Associations with cardiac markers, histology, and function in human non-ischaemic heart failure., PMID:36717981

How Carvedilol activates β2-adrenoceptors., PMID:36402762

Nanobody GPS by PCS: An Efficient New NMR Analysis Method for G Protein Coupled Receptors and Other Large Proteins., PMID:36394272

Macrophage polarization is involved in liver fibrosis induced by β 1-adrenoceptor autoantibody., PMID:35983976

Autoantibodies and Cardiomyopathy: Focus on Beta-1 Adrenergic Receptor Autoantibodies., PMID:35323150

Autoinflammation leading to autoimmunity in adult-onset Still's disease: more than simple coincidence?, PMID:34544497

Role of Anti-Beta-1-Adrenergic Receptor Antibodies in Cardiac Dysfunction in Patients with Cirrhotic Cardiomyopathy., PMID:34417673

High-mass MALDI-MS unravels ligand-mediated G protein-coupling selectivity to GPCRs., PMID:34326250

Autoimmune dysautonomia in women with silicone breast implants., PMID:33799099

Disturbance of myocardial metabolism participates in autoantibodies against β1 -adrenoceptor-induced cardiac dysfunction., PMID:33565091

M2 muscarinic autoantibodies and thyroid hormone promote susceptibility to atrial fibrillation and sinus tachycardia in an autoimmune rabbit model., PMID:33550676

The IgG3 subclass of β1-adrenergic receptor autoantibodies is an endogenous biaser of β1AR signaling., PMID:33534612

β1-adrenergic and Muscarinic Acetylcholine Type 2 Receptor Antibodies are Increased in Graves' Hyperthyroidism and Decrease During Antithyroid Therapy., PMID:33434937

β1-Adrenoceptor antibodies induce PPCM via inhibition of PGC-1α related pathway., PMID:33412941

GPCR Activation States Induced by Nanobodies and Mini-G Proteins Compared by NMR Spectroscopy., PMID:33348734

Autoantibodies against M5-muscarinic and beta1-adrenergic receptors in periodontitis patients., PMID:32857064

Molecular basis of β-arrestin coupling to formoterol-bound β1-adrenoceptor., PMID:32555462

β1 adrenoceptor antibodies induce myocardial apoptosis via inhibiting PGC-1α-related pathway., PMID:32503464

Unmasking features of the auto-epitope essential for β1 -adrenoceptor activation by autoantibodies in chronic heart failure., PMID:32436653

Arresting Developments in Biased Signaling., PMID:32362341

β1-Adrenoreceptor Autoantibodies in Heart Failure: Physiology and Therapeutic Implications., PMID:31957469

Suppression of β1-Adrenoceptor Autoantibodies is Involved in the Antiarrhythmic Effects of Omega-3 Fatty Acids in Male and Female Hypertensive Rats., PMID:31947691

The relationship between β1 -adrenergic and M2 -muscarinic receptor autoantibodies and hypertrophic cardiomyopathy., PMID:31808213

Nanodiscs Incorporating Native β1 Adrenergic Receptor as a Novel Approach for the Detection of Pathological Autoantibodies in Patients with Dilated Cardiomyopathy., PMID:31659076

Lowered anti-beta1 adrenergic receptor antibody concentrations may have prognostic significance in acute coronary syndrome., PMID:31601947

Endoplasmic reticulum stress contributed to β1-adrenoceptor autoantibody-induced reduction of autophagy in cardiomyocytes., PMID:31553425

Adrenergic Autoantibody-Induced Postural Tachycardia Syndrome in Rabbits., PMID:31547749

Doberman pinschers present autoimmunity associated with functional autoantibodies: A model to study the autoimmune background of human dilated cardiomyopathy., PMID:31276517

Molecular basis for high-affinity agonist binding in GPCRs., PMID:31072904

Multiple Autoantibodies against Cardiovascular Receptors as Biomarkers in Hypertensive Heart Disease., PMID:30982037

Activation of T Lymphocytes as a Novel Mechanism in Beta1-Adrenergic Receptor Autoantibody-Induced Cardiac Remodeling-Additional Information About TLR9 Involvement., PMID:30880373

Anti-ß1-Adrenoreceptor auto-Antibodies in elderly heart failure patients., PMID:30844728

Autoantibody against β1-adrenoceptor promotes the differentiation of natural regulatory T cells from activated CD4+ T cells by up-regulating AMPK-mediated fatty acid oxidation., PMID:30770790

Autoantibodies Against β1-Adrenoceptor Exaggerated Ventricular Remodeling by Inhibiting CTRP9 Expression., PMID:30764693

Activation of T Lymphocytes as a Novel Mechanism in Beta1-Adrenergic Receptor Autoantibody-Induced Cardiac Remodeling., PMID:30747396

Pro-remodeling effect of autoantibody against β1-adrenoceptor on cardiomyocytes involves T cells dysfunction under the pathological condition of heart failure., PMID:30678811

Beta-1-Adrenergic Receptor Antibodies in Acute Coronary Syndrome: Is Less Sometimes More?, PMID:30619882

No evidence for humoral autoimmunity against cardiomyocytes, adrenergic or muscarinic receptors in patients with Tako-Tsubo cardiomyopathy., PMID:30554740

Cyclic peptide RD808 reduces myocardial injury induced by β1-adrenoreceptor autoantibodies., PMID:30554265

Determination of Agonistically Acting Autoantibodies to the Adrenergic Beta-1 Receptor by Cellular Bioassay., PMID:30539571

Functional autoantibody diseases: Basics and treatment related to cardiomyopathies., PMID:30468647

Beta1-adrenergic receptor antibodies in children with dilated cardiomyopathy., PMID:30468641

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