Catalog No.
PMK97101
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Mouse ST14 (Ser213-Ser449).
Applications
ELISA, IHC, WB
Recommended Dilution
| Application |
Dilution |
| ELISA |
1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000 |
Target
Suppressor of tumorigenicity 14 protein homolog (EC 3.4.21.109) (Epithin) (Serine protease 14)
Purification
Purified by antigen affinity column.
Accession
P56677
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Note
For research use only.
Peptide immunocytochemistry in afferent neurons from lower gut in rats., PMID:3067223
Yeast artificial chromosomes with 200- to 800-kilobase inserts of human DNA containing HLA, V kappa, 5S, and Xq24-Xq28 sequences., PMID:2537978
Regulation of the activity of matriptase on epithelial cell surfaces by a blood-derived factor., PMID:11231297
Tissue microarray analysis of hepatocyte growth factor/Met pathway components reveals a role for Met, matriptase, and hepatocyte growth factor activator inhibitor 1 in the progression of node-negative breast cancer., PMID:12615728
Protein interaction analysis of ST14 domains and their point and deletion mutants., PMID:16407223
The cytotrophoblast layer of human chorionic villi becomes thinner but maintains its structural integrity during gestation., PMID:17035639
Autoactivation of matriptase in vitro: requirement for biomembrane and LDL receptor domain., PMID:17344310
Coordinate expression and functional profiling identify an extracellular proteolytic signaling pathway., PMID:17389401
Improving the species cross-reactivity of an antibody using computational design., PMID:19477127
Tumor detection by imaging proteolytic activity., PMID:20145119
Soluble epithin/PRSS14 secreted from cancer cells contains active angiogenic potential., PMID:20652801
Activity and inhibition of prostasin and matriptase on apical and basolateral surfaces of human airway epithelial cells., PMID:22582115
Overexpression of matriptase correlates with poor prognosis in esophageal squamous cell carcinoma., PMID:24248283
The differential impact of coadministered vaccines, geographic region, vaccine product and other covariates on pneumococcal conjugate vaccine immunogenicity., PMID:24336055
Proteases as activators for cytotoxic prodrugs in antitumor therapy., PMID:24709544
Differential subcellular localization renders HAI-2 a matriptase inhibitor in breast cancer cells but not in mammary epithelial cells., PMID:25786220
Capsular Polysaccharide (CPS) Release by Serotype 3 Pneumococcal Strains Reduces the Protective Effect of Anti-Type 3 CPS Antibodies., PMID:26677201
Ibuprofen regulates the expression and function of membrane-associated serine proteases prostasin and matriptase., PMID:26715240
Matriptase Induction of Metalloproteinase-Dependent Aggrecanolysis In Vitro and In Vivo: Promotion of Osteoarthritic Cartilage Damage by Multiple Mechanisms., PMID:28464560
Tissue distribution and subcellular localizations determine in vivo functional relationship among prostasin, matriptase, HAI-1, and HAI-2 in human skin., PMID:29438412
Targeting metastatic breast cancer with peptide epitopes derived from autocatalytic loop of Prss14/ST14 membrane serine protease and with monoclonal antibodies., PMID:31426843
Intramembrane proteolysis of an extracellular serine protease, epithin/PRSS14, enables its intracellular nuclear function., PMID:32493324
Sequential Linkage of Carbohydrate Antigens to Mimic Capsular Polysaccharides: Toward Semisynthetic Glycoconjugate Vaccine Candidates against Streptococcus pneumoniae Serotype 14., PMID:32835479
MCAM+ brain endothelial cells contribute to neuroinflammation by recruiting pathogenic CD4+ T lymphocytes., PMID:36319587
A study on viruses and bacteria with particular interest on Mycoplasma pneumoniae in children with exacerbation of asthma from a tertiary care hospital in Sri Lanka., PMID:39081780
For research use only. Not for human or drug use.
