Anti-Mouse ERAP1 Polyclonal Antibody

Catalog No.

PMK71201

Species reactivity

Mouse

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Mouse ERAP1 (Glu45-Asp226).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Endoplasmic reticulum aminopeptidase 1 (EC 3.4.11.-) (ARTS-1) (Adipocyte-derived leucine aminopeptidase) (A-LAP) (Aminopeptidase PILS) (Puromycin-insensitive leucyl-specific aminopeptidase) (PILS-AP) (VEGF-induced aminopeptidase)

Purification

Purified by antigen affinity column.

Accession

Q9EQH2

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Association of ERAP1 and ERAP2 gene polymorphisms and ERAP2 protein with the susceptibility and severity of rheumatoid arthritis in the Ukrainian population., PMID:39906739

ERAP1 and ERAP2 gene variants as potential clinical biomarkers of anti-interleukin-17A response in psoriasis vulgaris., PMID:38616723

ERAP-1 and ERAP-2 Variants in Liver Injury After COVID-19 mRNA Vaccination: A US Multicenter Study., PMID:38314748

Serum biomarkers and their relationship to axial spondyloarthritis associated with inflammatory bowel diseases., PMID:38168574

ERAP/HLA-C and KIR Genetic Profile in Couples with Recurrent Implantation Failure., PMID:36293373

Allotypic variation in antigen processing controls antigenic peptide generation from SARS-CoV-2 S1 spike glycoprotein., PMID:34688668

Paradoxical psoriasis induced by TNF-α blockade shows immunological features typical of the early phase of psoriasis development., PMID:31577850

HLA-C*06:02 genotype is a predictive biomarker of biologic treatment response in psoriasis., PMID:30578879

Behçet's disease: An immunogenetic perspective., PMID:30341905

Polymorphisms in CD84, IL12B and TNFAIP3 are associated with response to biologics in patients with psoriasis., PMID:27564082

Polymorphisms in STAT-4, IL-10, PSORS1C1, PTPN2 and MIR146A genes are associated differently with prognostic factors in Italian patients affected by rheumatoid arthritis., PMID:27342690

ERAP1 reduces accumulation of aberrant and disulfide-linked forms of HLA-B27 on the cell surface., PMID:27107845

A Pharmacogenetic Study of Psoriasis Risk Variants in a Greek Population and Prediction of Responses to Anti-TNF-α and Anti-IL-12/23 Agents., PMID:27043841

KIR3DL1 interaction with HLA-B27 is altered by ankylosing spondylitis associated ERAP1 and enhanced by MHC class I cross-linking., PMID:26321090

Silencing or inhibition of endoplasmic reticulum aminopeptidase 1 (ERAP1) suppresses free heavy chain expression and Th17 responses in ankylosing spondylitis., PMID:26130142

Endoplasmic reticulum-associated amino-peptidase 1 and rheumatic disease: genetics., PMID:26002026

Genetics of vasculitis., PMID:25405820

A multilocus genetic study in a cohort of Italian SLE patients confirms the association with STAT4 gene and describes a new association with HCP5 gene., PMID:25369137

TLR-mediated secretion of endoplasmic reticulum aminopeptidase 1 from macrophages., PMID:24688025

Critical role of endoplasmic reticulum aminopeptidase 1 in determining the length and sequence of peptides bound and presented by HLA-B27., PMID:24504800

[Genetic risk factors for vasculitis]., PMID:24217527

Endoplasmic reticulum aminopeptidase 1 (ERAP1) exhibits functionally significant interaction with HLA-B27 and relates to subtype specificity in ankylosing spondylitis., PMID:22355039

Expression of MHC class I dimers and ERAP1 in an ankylosing spondylitis patient cohort., PMID:21574996

Identification of novel susceptibility Loci for kawasaki disease in a Han chinese population by a genome-wide association study., PMID:21326860

Natural killer cells efficiently reject lymphoma silenced for the endoplasmic reticulum aminopeptidase associated with antigen processing., PMID:21252114

Down-regulation of proteasomal subunit MB1 is an independent predictor of improved survival in ovarian cancer., PMID:19243813

The role of endoplasmic reticulum-associated aminopeptidase 1 in immunity to infection and in cross-presentation., PMID:17277129

Localization of angiotensin II, the AT1 receptor, angiotensin-converting enzyme, aminopeptidase A, adipocyte-derived leucine aminopeptidase, and vascular endothelial growth factor in the human ovary throughout the menstrual cycle., PMID:16769060

Endoplasmic reticulum aminopeptidase-1 mediates leukemia inhibitory factor-induced cell surface human leukocyte antigen-G expression in JEG-3 choriocarcinoma cells., PMID:16439450

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