Catalog No.
PMJ75601
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Mouse IL36A/IL-1F6 (Met1-His160).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Interleukin-36 alpha (FIL1 epsilon) (Interleukin-1 epsilon) (IL-1 epsilon) (Interleukin-1 family member 6) (IL-1F6) (Interleukin-1 homolog 1) (IL-1H1)
Purification
Purified by antigen affinity column.
Accession
Q9JLA2
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Epicutaneous Staphylococcus aureus induces IL-36 to enhance IgE production and ensuing allergic disease., PMID:33645549
IL-1R3 blockade broadly attenuates the functions of six members of the IL-1 family, revealing their contribution to models of disease., PMID:31427775
Interleukin-36 alpha levels are elevated in the serum and cerebrospinal fluid of patients with neuromyelitis optica spectrum disorder and correlate with disease activity., PMID:30852049
Inhibiting Interleukin 36 Receptor Signaling Reduces Fibrosis in Mice With Chronic Intestinal Inflammation., PMID:30452921
IL-36 receptor antagonistic antibodies inhibit inflammatory responses in preclinical models of psoriasiform dermatitis., PMID:30417427
First-in-Human Study of AMG 820, a Monoclonal Anti-Colony-Stimulating Factor 1 Receptor Antibody, in Patients with Advanced Solid Tumors., PMID:28655795
Correlation between IL36α and IL17 and Activity of the Disease in Selected Autoimmune Blistering Diseases., PMID:28611508
IL-36R signalling activates intestinal epithelial cells and fibroblasts and promotes mucosal healing in vivo., PMID:26783184
Canakinumab in adults with steroid-refractory pyoderma gangrenosum., PMID:26471257
Anti-CSF-1 treatment is effective to prevent carcinoma invasion induced by monocyte-derived cells but scarcely by microglia., PMID:26098772
For research use only. Not for human or drug use.
