Catalog No.
PMH33401
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Mouse PRSS8 (Gln42-Val311).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Prostasin, Protease, serine 8 (prostasin), Protease, serine, 8 (Prostasin), Prss8
Purification
Purified by antigen affinity column.
Accession
Q99L44
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
A mouse testis serine protease, TESP1, as the potential SPINK3 receptor protein on mouse sperm acrosome., PMID:34524424
The epithelial Na+ channel α- and γ-subunits are cleaved at predicted furin-cleavage sites, glycosylated and membrane associated in human kidney., PMID:31654198
Tissue distribution and subcellular localizations determine in vivo functional relationship among prostasin, matriptase, HAI-1, and HAI-2 in human skin., PMID:29438412
Proteolytic cleavages in the extracellular domain of receptor tyrosine kinases by membrane-associated serine proteases., PMID:28915606
Selective Inhibition of Prostasin in Human Enterocytes by the Integral Membrane Kunitz-Type Serine Protease Inhibitor HAI-2., PMID:28125689
Natural Endogenous Human Matriptase and Prostasin Undergo Zymogen Activation via Independent Mechanisms in an Uncoupled Manner., PMID:27936035
Matriptase and prostasin are expressed in human skin in an inverse trend over the course of differentiation and are targeted to different regions of the plasma membrane., PMID:27543057
Matriptase Complexes and Prostasin Complexes with HAI-1 and HAI-2 in Human Milk: Significant Proteolysis in Lactation., PMID:27043831
Ibuprofen regulates the expression and function of membrane-associated serine proteases prostasin and matriptase., PMID:26715240
Diabetic nephropathy is associated with increased urine excretion of proteases plasmin, prostasin and urokinase and activation of amiloride-sensitive current in collecting duct cells., PMID:25609736
Prostasin interacts with the epithelial Na+ channel and facilitates cleavage of the γ-subunit by a second protease., PMID:25209858
Increased expression of prostasin contributes to early-onset severe preeclampsia through inhibiting trophoblast invasion., PMID:25078863
The epithelial sodium channel γ-subunit is processed proteolytically in human kidney., PMID:25060057
Activity and inhibition of prostasin and matriptase on apical and basolateral surfaces of human airway epithelial cells., PMID:22582115
Prostasin inhibits cell invasion in human choriocarcinomal JEG-3 cells., PMID:19847458
Prostasin-dependent activation of epithelial Na+ channels by low plasmin concentrations., PMID:19793956
Hepatocyte growth factor activator inhibitor-1 (HAI-1) is essential for the integrity of basement membranes in the developing placental labyrinth., PMID:17174946
Gene expression profiling separates chromophobe renal cell carcinoma from oncocytoma and identifies vesicular transport and cell junction proteins as differentially expressed genes., PMID:17145811
Long-term effects of vasopressin on the subcellular localization of ENaC in the renal collecting system., PMID:16528252
Activation of epithelial sodium channels by mouse channel activating proteases (mCAP) expressed in Xenopus oocytes requires catalytic activity of mCAP3 and mCAP2 but not mCAP1., PMID:16524950
Mouse prostasin gene structure, promoter analysis, and restricted expression in lung and kidney., PMID:12959947
Down-regulated expression of prostasin in high-grade or hormone-refractory human prostate cancers., PMID:12518323
Structure and activity of human pancreasin, a novel tryptic serine peptidase expressed primarily by the pancreas., PMID:12441343
Synergistic activation of ENaC by three membrane-bound channel-activating serine proteases (mCAP1, mCAP2, and mCAP3) and serum- and glucocorticoid-regulated kinase (Sgk1) in Xenopus Oocytes., PMID:12149280
Involvement of phosphorylation of Tyr-31 and Tyr-118 of paxillin in MM1 cancer cell migration., PMID:11774284
Prostasin, a potential serum marker for ovarian cancer: identification through microarray technology., PMID:11584061
Prostasin is a glycosylphosphatidylinositol-anchored active serine protease., PMID:11274175
Testisin, a new human serine proteinase expressed by premeiotic testicular germ cells and lost in testicular germ cell tumors., PMID:10397266
Cystic fibrosis transmembrane conductance regulator inhibits epithelial Na+ channels carrying Liddle's syndrome mutations., PMID:10318798
Anti-human prostasome MAB 78 binds to antigen distinct from PSA and PAP., PMID:9112566
For research use only. Not for human or drug use.
