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Anti-Mouse IL1RL1/ST2 Polyclonal Antibody

Catalog #:   PMF88301 Specific References (100) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: P14719
Overview

Catalog No.

PMF88301

Species reactivity

Mouse

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Mouse IL1RL1/ST2 (Ser27-Arg332).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Interleukin-1 receptor-like 1 (EC 3.2.2.6) (Interleukin-33 receptor alpha chain) (Lymphocyte antigen 84) (Protein ST2) (Protein T1)

Purification

Purified by antigen affinity column.

Accession

P14719

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Various lysates were subjected to SDS PAGE followed by western blot with IL1RL1 antibody (PMF88301) at 1µg/ml.

    Lane 1: Hela cell lysate
    Lane 2: SGC-7901 cell lysate
    Lane 3: HUVEC cell lysate
    Lane 4: HepG2 cell lysate
    Lane 5: Mouse brain lysate

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 65 kDa
    Observed MW: 48 kDa
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with IL1RL1/ST2 antibody (PMF88301) at 1 µg/ml.

    Lane 1: Recombinant Protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 37 kDa
    Observed MW: 37 kDa
References

Enhancing the Affinity of a Novel Selective scFv for Soluble ST2 through Computational Design., PMID:40417773

Enhancing the Affinity of a Novel Selective scFv for Soluble ST2 through Computational Design., PMID:40417773

Fluorescence Aptasensor for sST2 Detection Using In Vitro Selected Aptamers., PMID:40370093

Fluorescence Aptasensor for sST2 Detection Using In Vitro Selected Aptamers., PMID:40370093

Drug survival of omalizumab in atopic asthma: Impact of clinical and genetic variables., PMID:40189906

Drug survival of omalizumab in atopic asthma: Impact of clinical and genetic variables., PMID:40189906

A novel optical fiber immunosensor for detection of heart failure marker ST2 based on MoS2-modified D-shaped ExTFG., PMID:40120516

A novel optical fiber immunosensor for detection of heart failure marker ST2 based on MoS2-modified D-shaped ExTFG., PMID:40120516

Soluble ST2 is an early marker and treatment target for hypertensive nephrosclerosis signatured in glomerular mesangial cells., PMID:40096886

Soluble ST2 is an early marker and treatment target for hypertensive nephrosclerosis signatured in glomerular mesangial cells., PMID:40096886

IL-33 protects from recurrent C. difficile infection by restoration of humoral immunity., PMID:40048372

IL-33 protects from recurrent C. difficile infection by restoration of humoral immunity., PMID:40048372

IL-33 signaling is dispensable for the IL-10-induced enhancement of mast cell responses during food allergy., PMID:39935481

IL-33 signaling is dispensable for the IL-10-induced enhancement of mast cell responses during food allergy., PMID:39935481

IL-33/ST2 axis in diverse diseases: regulatory mechanisms and therapeutic potential., PMID:39925809

IL-33/ST2 axis in diverse diseases: regulatory mechanisms and therapeutic potential., PMID:39925809

IL-33/ST2 axis mediates diesel exhaust particles-induced mast cell activation., PMID:39707175

IL-33/ST2 axis mediates diesel exhaust particles-induced mast cell activation., PMID:39707175

Group 2 innate lymphoid cells are a non-redundant source of interleukin-5 required for development and function of murine B1 cells., PMID:39632879

Group 2 innate lymphoid cells are a non-redundant source of interleukin-5 required for development and function of murine B1 cells., PMID:39632879

Dural Tregs driven by astrocytic IL-33 mitigate depression through the EGFR signals in mPFC neurons., PMID:39592709

Dural Tregs driven by astrocytic IL-33 mitigate depression through the EGFR signals in mPFC neurons., PMID:39592709

Interleukin-33 Deficiency Protects the Skin From Ulcer Formation in an Ischemia-Reperfusion-Induced Decubitus Mouse Model., PMID:39555678

Interleukin-33 Deficiency Protects the Skin From Ulcer Formation in an Ischemia-Reperfusion-Induced Decubitus Mouse Model., PMID:39555678

IL-33/ST2 enhances MMP-12 expression by macrophages to mediate inflammatory and immune response in IgG4-Related Ophthalmic Disease., PMID:39299101

IL-33/ST2 enhances MMP-12 expression by macrophages to mediate inflammatory and immune response in IgG4-Related Ophthalmic Disease., PMID:39299101

A model-based approach using GSK3772847, an anti-interleukin-33 receptor monoclonal antibody, as a showcase to predict SC administration PK and free target dynamics based on PK and total target measurements after IV administration., PMID:39258338

A model-based approach using GSK3772847, an anti-interleukin-33 receptor monoclonal antibody, as a showcase to predict SC administration PK and free target dynamics based on PK and total target measurements after IV administration., PMID:39258338

Population pharmacokinetic/target engagement modelling of tozorakimab in healthy volunteers and patients with chronic obstructive pulmonary disease., PMID:39183511

Population pharmacokinetic/target engagement modelling of tozorakimab in healthy volunteers and patients with chronic obstructive pulmonary disease., PMID:39183511

Edwardsiella tarda induces airways inflammation and production of autoantibodies against lung tissues through regulation of the IL-33-ST2 axis., PMID:39126327

Edwardsiella tarda induces airways inflammation and production of autoantibodies against lung tissues through regulation of the IL-33-ST2 axis., PMID:39126327

SingleNucleotide Polymorphisms as Biomarkers of Mepolizumab and Benralizumab Treatment Response in Severe Eosinophilic Asthma., PMID:39125709

SingleNucleotide Polymorphisms as Biomarkers of Mepolizumab and Benralizumab Treatment Response in Severe Eosinophilic Asthma., PMID:39125709

ILC2s induce Treg but not Th2-type immunity through IL-33/ST2 pathway in pulmonary tuberculosis., PMID:38990986

ILC2s induce Treg but not Th2-type immunity through IL-33/ST2 pathway in pulmonary tuberculosis., PMID:38990986

The IL-33-ST2 axis plays a vital role in endometriosis via promoting epithelial-mesenchymal transition by phosphorylating β-catenin., PMID:38858740

The IL-33-ST2 axis plays a vital role in endometriosis via promoting epithelial-mesenchymal transition by phosphorylating β-catenin., PMID:38858740

Maintenance of caecal homeostasis by diverse adaptive immune cells in the rhesus macaque., PMID:38707998

Maintenance of caecal homeostasis by diverse adaptive immune cells in the rhesus macaque., PMID:38707998

Hydrangea serrata extract attenuates PM-exacerbated airway inflammation in the CARAS model by modulating the IL-33/ST2/NF-κB signaling pathway., PMID:38631146

Hydrangea serrata extract attenuates PM-exacerbated airway inflammation in the CARAS model by modulating the IL-33/ST2/NF-κB signaling pathway., PMID:38631146

Multiplex Proteomics in the Identification of Potential Biomarkers of Very Severe Sinusoidal Obstruction Syndrome/Veno-Occlusive Disease in Allogeneic Hematopoietic Cell Transplant Patients Treated with Defibrotide., PMID:38330921

Multiplex Proteomics in the Identification of Potential Biomarkers of Very Severe Sinusoidal Obstruction Syndrome/Veno-Occlusive Disease in Allogeneic Hematopoietic Cell Transplant Patients Treated with Defibrotide., PMID:38330921

ST2-Mediated Neutrophilic Airway Inflammation: A Therapeutic Target for Patients With Uncontrolled Asthma., PMID:38262389

ST2-Mediated Neutrophilic Airway Inflammation: A Therapeutic Target for Patients With Uncontrolled Asthma., PMID:38262389

Interleukin-33/ST2 axis involvement in atrial remodeling and arrhythmogenesis., PMID:38244770

Interleukin-33/ST2 axis involvement in atrial remodeling and arrhythmogenesis., PMID:38244770

Strategies targeting IL-33/ST2 axis in the treatment of allergic diseases., PMID:37981174

Strategies targeting IL-33/ST2 axis in the treatment of allergic diseases., PMID:37981174

Oxidised IL-33 drives COPD epithelial pathogenesis via ST2-independent RAGE/EGFR signalling complex., PMID:37442582

Oxidised IL-33 drives COPD epithelial pathogenesis via ST2-independent RAGE/EGFR signalling complex., PMID:37442582

Influence of Genetics on the Response to Omalizumab in Patients with Severe Uncontrolled Asthma with an Allergic Phenotype., PMID:37108192

Influence of Genetics on the Response to Omalizumab in Patients with Severe Uncontrolled Asthma with an Allergic Phenotype., PMID:37108192

Interleukin-33 Mediates Cardiomyopathy After Acute Kidney Injury by Signaling to Cardiomyocytes., PMID:36695175

Interleukin-33 Mediates Cardiomyopathy After Acute Kidney Injury by Signaling to Cardiomyocytes., PMID:36695175

A comparative study of IL-33 and its receptor ST2 in a C57BL/6 J mouse model of pulmonary Cryptococcus neoformans infection., PMID:36367554

A comparative study of IL-33 and its receptor ST2 in a C57BL/6 J mouse model of pulmonary Cryptococcus neoformans infection., PMID:36367554

Phase 2 randomized clinical trial of astegolimab in patients with moderate to severe atopic dermatitis., PMID:36041655

Phase 2 randomized clinical trial of astegolimab in patients with moderate to severe atopic dermatitis., PMID:36041655

IL11 Stimulates IL33 Expression and Proinflammatory Fibroblast Activation across Tissues., PMID:36012165

IL11 Stimulates IL33 Expression and Proinflammatory Fibroblast Activation across Tissues., PMID:36012165

IL-33/ST2 axis contributes to the dermal fibrosis of systemic sclerosis via promoting fibroblasts activation., PMID:35940987

IL-33/ST2 axis contributes to the dermal fibrosis of systemic sclerosis via promoting fibroblasts activation., PMID:35940987

Interleukin-33 (IL-33): A critical review of its biology and the mechanisms involved in its release as a potent extracellular cytokine., PMID:35640416

Interleukin-33 (IL-33): A critical review of its biology and the mechanisms involved in its release as a potent extracellular cytokine., PMID:35640416

A rapid and quantitative detection method for plasma soluble growth stimulating gene protein 2 based on time resolved fluorescence immunochromatography., PMID:35608240

A rapid and quantitative detection method for plasma soluble growth stimulating gene protein 2 based on time resolved fluorescence immunochromatography., PMID:35608240

Increased expression of IL1-RL1 is associated with type 2 and type 1 immune pathways in asthma., PMID:35578178

Increased expression of IL1-RL1 is associated with type 2 and type 1 immune pathways in asthma., PMID:35578178

IL-25 blockade augments antiviral immunity during respiratory virus infection., PMID:35508632

IL-25 blockade augments antiviral immunity during respiratory virus infection., PMID:35508632

The Merkel Cell Polyomavirus T-Antigens and IL-33/ST2-IL1RAcP Axis: Possible Role in Merkel Cell Carcinoma., PMID:35409061

The Merkel Cell Polyomavirus T-Antigens and IL-33/ST2-IL1RAcP Axis: Possible Role in Merkel Cell Carcinoma., PMID:35409061

Mast Cells Differentiated in Synovial Fluid and Resident in Osteophytes Exalt the Inflammatory Pathology of Osteoarthritis., PMID:35008966

Mast Cells Differentiated in Synovial Fluid and Resident in Osteophytes Exalt the Inflammatory Pathology of Osteoarthritis., PMID:35008966

Blockade or deficiency of PD-L1 expression in intestinal allograft accelerates graft tissue injury in mice., PMID:34679256

Blockade or deficiency of PD-L1 expression in intestinal allograft accelerates graft tissue injury in mice., PMID:34679256

Gut Microbial Metabolite Pravastatin Attenuates Intestinal Ischemia/Reperfusion Injury Through Promoting IL-13 Release From Type II Innate Lymphoid Cells via IL-33/ST2 Signaling., PMID:34650552

Gut Microbial Metabolite Pravastatin Attenuates Intestinal Ischemia/Reperfusion Injury Through Promoting IL-13 Release From Type II Innate Lymphoid Cells via IL-33/ST2 Signaling., PMID:34650552

Inhibition of NF-κB/IL-33/ST2 Axis Ameliorates Acute Bronchiolitis Induced by Respiratory Syncytial Virus., PMID:34395633

Inhibition of NF-κB/IL-33/ST2 Axis Ameliorates Acute Bronchiolitis Induced by Respiratory Syncytial Virus., PMID:34395633

Role of the IL33 and IL1RL1 pathway in the pathogenesis of Immunoglobulin A vasculitis., PMID:34373564

Role of the IL33 and IL1RL1 pathway in the pathogenesis of Immunoglobulin A vasculitis., PMID:34373564

Safety and efficacy of itepekimab in patients with moderate-to-severe COPD: a genetic association study and randomised, double-blind, phase 2a trial., PMID:34302758

Safety and efficacy of itepekimab in patients with moderate-to-severe COPD: a genetic association study and randomised, double-blind, phase 2a trial., PMID:34302758

Astegolimab (anti-ST2) efficacy and safety in adults with severe asthma: A randomized clinical trial., PMID:33872652

Astegolimab (anti-ST2) efficacy and safety in adults with severe asthma: A randomized clinical trial., PMID:33872652

The IL33 receptor ST2 contributes to mechanical hypersensitivity in mice with neuropathic pain., PMID:33596932

The IL33 receptor ST2 contributes to mechanical hypersensitivity in mice with neuropathic pain., PMID:33596932

Role of the IL-33/ST2 axis in cigarette smoke-induced airways remodelling in chronic obstructive pulmonary disease., PMID:33589512

Role of the IL-33/ST2 axis in cigarette smoke-induced airways remodelling in chronic obstructive pulmonary disease., PMID:33589512

Endothelial cells response to neutrophil-derived extracellular vesicles miRNAs in anti-PR3 positive vasculitis., PMID:33527387

Endothelial cells response to neutrophil-derived extracellular vesicles miRNAs in anti-PR3 positive vasculitis., PMID:33527387

Persistence of mature dendritic cells, TH2A, and Tc2 cells characterize clinically resolved atopic dermatitis under IL-4Rα blockade., PMID:33483337

Persistence of mature dendritic cells, TH2A, and Tc2 cells characterize clinically resolved atopic dermatitis under IL-4Rα blockade., PMID:33483337

Nuclear IL-33 restrains the early conversion of fibroblasts to an extracellular matrix-secreting phenotype., PMID:33420328

Nuclear IL-33 restrains the early conversion of fibroblasts to an extracellular matrix-secreting phenotype., PMID:33420328

Development of a Novel Homogeneous Nanoparticle-Based Assay for Rapid and High-Throughput Quantitation of the sST2 Protein in Human Serum., PMID:33408473

Development of a Novel Homogeneous Nanoparticle-Based Assay for Rapid and High-Throughput Quantitation of the sST2 Protein in Human Serum., PMID:33408473

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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Anti-Mouse IL1RL1/ST2 Polyclonal Antibody [PMF88301]
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