Catalog No.
PMD27401
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Mouse FLT1/VEGFR1 (Gly38-Thr227).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Embryonic receptor kinase 2) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase receptor FLT)
Purification
Purified by antigen affinity column.
Accession
P35969
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Beyond antibodies: Beta-2 glycoprotein I as the unsung guardian of pregnancy., PMID:40279303
Immunoexpression of placental growth factor (PlGF) and soluble FMS-like tyrosine kinase 1 (sFlt-1) in the placental bed of preeclamptic women of African ancestry living with HIV infection., PMID:39579213
Placenta-associated biomarkers and pregnancy outcome in HPA-1a alloimmunization: A prospective cohort study., PMID:39486121
Proteomic and serological markers for diagnosing cardia gastric cancer and precursor lesions in a Chinese population., PMID:39455684
Maternal Thyroid Function and Biochemical Markers of Placental Function in Early Pregnancy., PMID:39370704
Therapeutic effect of E-Lip-siRNA-sFlt1 on pre-eclampsia: targeted gene silencing and improved pregnancy outcomes., PMID:39016060
Short Term Effect of Pre-Operative Anti-VEGF on Angiogenic and Fibrotic Profile of Fibrovascular Membranes of Proliferative Diabetic Retinopathy., PMID:38652648
Molecular Basis of Angiogenesis and its Application., PMID:38522916
Predictive value of CDC37 gene expression for targeted therapy in metastatic colorectal cancer., PMID:38359495
Influence of Genetic Polymorphisms on the Short-Term Response to Ranibizumab in Patients With Neovascular Age-Related Macular Degeneration., PMID:37862026
Comprehensive molecular analysis to predict the efficacy of chemotherapy containing bevacizumab in patients with metastatic colorectal cancer., PMID:37744267
Exosome-Based Cell Homing and Angiogenic Differentiation for Dental Pulp Regeneration., PMID:36613910
Soluble Flt-1 in AMI Patients Serum Inhibits Angiogenesis of Endothelial Progenitor Cells by Suppressing Akt and Erk's Activity., PMID:36009821
Genetic Polymorphisms in VEGFR Coding Genes (FLT1/KDR) on Ranibizumab Response in High Myopia and Choroidal Neovascularization Patients., PMID:35893809
Vascular Endothelial Growth Factor Receptor, fms-Like Tyrosine Kinase-1 (Flt-1), as a Novel Binding Partner for SARS-CoV-2 Spike Receptor-Binding Domain., PMID:35874709
Soluble factors secreted by human Wharton's jelly mesenchymal stromal/stem cells exhibit therapeutic radioprotection: A mechanistic study with integrating network biology., PMID:35722198
Placental lesions and differential expression of pro-and anti-angiogenic growth mediators and oxidative DNA damage marker in placentae of Ghanaian suboptimal and optimal health status pregnant women who later developed preeclampsia., PMID:35312727
Reduced placental size and increased apoptosis are associated with prenatal nicotine exposure in rats., PMID:35302204
Immunohistochemical expression of VEGFR1 in non small cell lung carcinomas: Lower VEGFR1 expression is asociated with squamous cell carcinoma subtype and high SUV max values in 18F-FDG PET., PMID:34991832
A simple detection method for the serum sFLT1 protein in preeclampsia., PMID:34663835
PIGF and Flt-1 on the surface of macrophages induces the production of TGF-β1 by polarized tumor-associated macrophages to promote lung cancer angiogenesis., PMID:34610279
VEGFR-1/Flt-1 inhibition increases angiogenesis and improves muscle function in a mouse model of Duchenne muscular dystrophy., PMID:33898634
Comparison of conbercept and ranibizumab combined mitomycin C-augmented trabeculectomy for neovascular glaucoma., PMID:33895882
System Genetics Including Causal Inference Identify Immune Targets for Coronary Artery Disease and the Lifespan., PMID:33625251
Relevance of angiogenesis in autoimmune testis inflammation., PMID:33313783
Pravastatin, proton-pump inhibitors, metformin, micronutrients, and biologics: new horizons for the prevention or treatment of preeclampsia., PMID:32946849
Beta2 glycoprotein I-derived therapeutic peptides induce sFlt-1 secretion to reduce melanoma vascularity and growth., PMID:32891714
The soluble VEGF receptor sFlt-1 contributes to endothelial dysfunction in IgA nephropathy., PMID:32790760
VEGF is an autocrine/paracrine neuroprotective factor for injured retinal ganglion neurons., PMID:32710087
Affinity-Enhanced Multimeric VEGF (Vascular Endothelial Growth Factor) and PlGF (Placental Growth Factor) Variants for Specific Adsorption of sFlt-1 to Restore Angiogenic Balance in Preeclampsia., PMID:32623922
Targeting the vascular endothelial growth factor receptor-1 by the monoclonal antibody D16F7 to increase the activity of immune checkpoint inhibitors against cutaneous melanoma., PMID:32485280
Detection of circulating natural antibodies against CD25, MUC1, and VEGFR1 for early diagnosis of non-small cell lung cancer., PMID:32392378
Simultaneous fluorescence imaging of distinct nerve and blood vessel patterns in dual Thy1-YFP and Flt1-DsRed transgenic mice., PMID:32372335
A Critical Review of Biological Properties, Delivery Systems and Analytical/Bioanalytical Methods for Determination of Bevacizumab., PMID:32295395
Vascular endothelial growth factor receptor 1 in glioblastoma‑associated microglia/macrophages., PMID:32236632
Anti-placental growth factor antibody ameliorates hyperoxia-mediated impairment of lung development in neonatal rats., PMID:31994602
Epidermal autonomous VEGFA/Flt1/Nrp1 functions mediate psoriasis-like disease., PMID:31934626
Reciprocal upregulation of hypoxia-inducible factor-1α and persistently enhanced placental adenosine signaling contribute to the pathogenesis of preeclampsia., PMID:31930569
Inhibition of FLT1 ameliorates muscular dystrophy phenotype by increased vasculature in a mouse model of Duchenne muscular dystrophy., PMID:31877123
A VEGF receptor vaccine demonstrates preliminary efficacy in neurofibromatosis type 2., PMID:31848332
VEGF/Flk1 Mechanism is Involved in Roxarsone Promotion of Rat Endothelial Cell Growth and B16F10 Xenograft Tumor Angiogenesis., PMID:31758020
Cerebral cavernomas in adults and children express relaxin., PMID:31756710
Monoclonal antibody AC10364 inhibits cell proliferation in 5-fluorouracil resistant hepatocellular carcinoma via apoptotic pathways., PMID:31303763
Detection and quantification of VEGFR-1 in the nuclei of tumor cells by a new flow cytometry-based method., PMID:30985194
Endothelial Cells Regulate Physiological Cardiomyocyte Growth via VEGFR2-Mediated Paracrine Signaling., PMID:30922063
Blockade of Vascular Endothelial Growth Factor Receptor-1 (Flt-1), Reveals a Novel Analgesic For Osteoarthritis-Induced Joint Pain., PMID:30873504
Protective Effect of TLR4 Ablation against Corneal Neovascularization following Chemical Burn in a Mouse Model., PMID:30595046
Decreased Expression of Vascular Endothelial Growth Factor Receptor 1 Contributes to the Pathogenesis of Hereditary Hemorrhagic Telangiectasia Type 2., PMID:30571259
Effects of VEGFR1+ hematopoietic progenitor cells on pre-metastatic niche formation and in vivo metastasis of breast cancer cells., PMID:30483898
Treatment with placental growth factor attenuates myocardial ischemia/reperfusion injury., PMID:30212490
For research use only. Not for human or drug use.
