Catalog No.
PHH19001
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human EFNB3 (Asn36-His133).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Ephrin-B3, LERK8, EPLG8, EFNB3, EPH-related receptor transmembrane ligand ELK-L3, EPH-related receptor tyrosine kinase ligand 8, LERK-8
Purification
Purified by antigen affinity column.
Accession
Q15768
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Ephrin-B1 regulates cell surface residency of heparan sulfate proteoglycans (HSPGs) and complexes with the HSPG CD44V3-10 and fibroblast growth factor receptors., PMID:40294072
Structure-guided mutagenesis of Henipavirus receptor-binding proteins reveals molecular determinants of receptor usage and antibody-binding epitopes., PMID:38426726
Structure guided mutagenesis of Henipavirus Receptor Binding Proteins reveals molecular determinants of receptor usage and antibody binding epitopes., PMID:38045373
In silico prediction of interaction between Nipah virus attachment glycoprotein and host cell receptors Ephrin-B2 and Ephrin-B3 in domestic and peridomestic mammals., PMID:37924857
A Recombinant Chimeric Cedar Virus-Based Surrogate Neutralization Assay Platform for Pathogenic Henipaviruses., PMID:37243163
May EPH/Ephrin Targeting Revolutionize Lung Cancer Treatment?, PMID:36613532
Cooperativity mediated by rationally selected combinations of human monoclonal antibodies targeting the henipavirus receptor binding protein., PMID:34469726
Sonic hedgehog pathway activation is associated with cetuximab resistance and EPHB3 receptor induction in colorectal cancer., PMID:31149041
Eph/ephrin signalling serves a bidirectional role in lipopolysaccharide‑induced intestinal injury., PMID:29901151
Identification and characterization of Nanobodies targeting the EphA4 receptor., PMID:28526745
Eph/ephrin-B-mediated cell-to-cell interactions govern MTS20(+) thymic epithelial cell development., PMID:27060907
Antibody-mediated neutralization of myelin-associated EphrinB3 accelerates CNS remyelination., PMID:26687980
Novel Functions of Hendra Virus G N-Glycans and Comparisons to Nipah Virus., PMID:25948743
Prolactin-induced protein (PIP) regulates proliferation of luminal A type breast cancer cells in an estrogen-independent manner., PMID:23755096
N-Glycans on the Nipah virus attachment glycoprotein modulate fusion and viral entry as they protect against antibody neutralization., PMID:22915812
Henipavirus mediated membrane fusion, virus entry and targeted therapeutics., PMID:22470837
Ephrin-B2 and ephrin-B3 as functional henipavirus receptors., PMID:22227101
Involvement of EphB/Ephrin-B signaling in axonal survival in mouse experimental glaucoma., PMID:22064993
Ephrin-B reverse signaling is required for formation of strictly contralateral auditory brainstem pathways., PMID:20660266
Axonal/glial upregulation of EphB/ephrin-B signaling in mouse experimental ocular hypertension., PMID:19815726
Epitope mapping of antibodies using bacterial surface display., PMID:19029907
Residues in the stalk domain of the hendra virus g glycoprotein modulate conformational changes associated with receptor binding., PMID:18799571
Functional studies of host-specific ephrin-B ligands as Henipavirus receptors., PMID:18054977
Identification of Hendra virus G glycoprotein residues that are critical for receptor binding., PMID:17376907
EphB/ephrin-B interaction mediates adult stem cell attachment, spreading, and migration: implications for dental tissue repair., PMID:17204606
Distribution of EphB receptors and ephrin-B1 in the developing vertebrate spinal cord., PMID:16786562
Ephrin B1 is expressed on human luteinizing granulosa cells in corpora lutea of the early luteal phase: the possible involvement of the B class Eph-ephrin system during corpus luteum formation., PMID:12970314
Human dendritic cells express neuronal Eph receptor tyrosine kinases: role of EphA2 in regulating adhesion to fibronectin., PMID:12907451
EphA4 provides repulsive signals to developing cochlear ganglion neurites mediated through ephrin-B2 and -B3., PMID:12761826
Lac z Histochemistry and immunohistochemistry reveal ephrin-B ligand expression in the inner ear., PMID:12486086
Ephrin B1 is expressed on neuroepithelial cells in correlation with neocortical neurogenesis., PMID:11306625
For research use only. Not for human or drug use.
